1986 - Bachelor's degree in Medicine: Fourth Military Medical University
1996 - Doctorate in Biochemistry and Molecular Biology: Shanghai Cancer Institute
1998-2006 - Postdoctoral and Senior Researcher in Germany and USA
2006-present - Minjiang Scholar Distinguished Professor, Doctoral Supervisor at Xiamen University
2012-present - Vice Dean of the School of Life Sciences, Deputy Director of the Molecular Diagnostics Engineering Research Center, Ministry of Education, Xiamen University
Poly(ADP-ribosyl)ation of OVOL2 regulates aneuploidy and cell death in cancer cells., Zhang R, Hong JJ, Yang Q, Ong CT, Li BA*, Liou YC*., 2018
Pygo2 regulates adiposity and glucose homeostasis via β-Catenin-Axin2-GSK3β signaling pathway., Xie YY, Mo CL, Cai YH, Wang WJ, Hong XX, Liu QF, Liu YJ, Hong JJ, He T, Zheng ZZ, and Li BA*., 2018
Tumor-originated exosomal lncUEGC1 as a circulating biomarker for early-stage gastric cancer., Lin LY, Yang L, Zeng Q, Wang L, Chen ML, Zhao ZH, Ye GD, Luo QC, Lv PY, Guo QW, Li BA*, Cai JC*, Cai WY*., 2018
PMP22 Regulates Self-Renewal and Chemoresistance of Gastric Cancer Cells., Cai W, Chen G, Luo Q, Liu J, Guo X, Zhang T, Ma F, Yuan L, Li BA*, Cai J*., 2017
Simultaneous detection of 45 fusion genes in leukemia by dual-color fluorescence real-time PCR., Zheng Z, Zhang P, He G, Liao K, Wang Z, Pan J, Du K, Du J, Li BA*., 2017
Ovol2 gene inhibits the Epithelial-to-Mesenchymal Transition in lung adenocarcinoma by transcriptionally repressing Twist1., Wang ZH, Li Z, Hu M, Yang QJ, Yan S, Wu RS, Li BA*, Guo M*., 2017
YAP-TEAD and HNF4α repress reciprocally to regulate hepatocarcinogenesis., Cai WY, Lin LY, Hao H, Zhang SM, Ma F, Hong XX, Zhang H, Liu QF, Ye GD, Sun GB, Liu YJ, Li SN, Xie YY, Cai JC, and Li BA*., 2017
Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway., Zhang ZM, Wu JF, Luo QC, Liu QF, Wu QW, Ye GD, She HQ*, and Li BA*., 2016
OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and is Downregulated in Human Colorectal Tumors., Ye GD, Sun GB, Jiao P, Chen C, Liu QF, Huang XL, Zhang R, Cai WY, Li SN, Wu JF, Liu YJ, Wu RS, Xie YY, Chan EC, Liou YC, and Li BA*., 2016
MicroRNA-20b promotes cell growth of breast cancer cells partly via targeting phosphatase and tensin homologue (PTEN)., Zhou W, Shi G, Zhang Q, Wu Q, Li B*, Zhang Z*., 2014
Downregulated Chibby in laryngeal squamous cell carcinoma with increased expression in laryngeal carcinoma Hep-2 cells., Xu J, Ren G, Zhao DA, Li BA, Cai CF, Zhou Y, Luo XY., 2014
Double-Negative Feedback Loop Between Wnt/β-catenin Signaling and HNF4α Regulates Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma., Yang M, Li SN, Anjum KM, Gui LX, Zhu SS, Liu J, Chen JK, Liu QF, Ye GD, Wang WJ, Wu JF, Cai WY, Sun GB, Liu YJ, Liu RF, Zhang ZM, Li BA*., 2013
Wnt/β-catenin pathway represses let-7 microRNAs expression via transactivation of Lin28 to augment breast cancer stem cell expansion., Cai WY, Wei TZ, Luo QC, Wu QW, Liu QF, Yang M, Ye GD, Wu JF, Chen YY, Sun GB, Liu YJ, Zhao WX, Zhang ZM, Li BA*., 2013
A novel tumor suppressor miRNA miR-520e contributes to suppression of hepatoma., Li BA*., 2012
The orphan receptor TR3 suppresses intestinal tumorigenesis in mice by downregulating Wnt signalling., Chen HZ, Liu QF, Li L, Wang WJ, Yao LM, Yang M, Liu B, Chen W, Zhan YY, Zhang MQ, Cai JC, Zheng ZH, Lin SC, Li BA*, Wu Q*., 2012
Pygo2 associates with MLL2 histone methyltransferase (HMT) and GCN5 histone acetyltransferase (HAT) complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion., Chen J, Luo Q, Yuan Y, Huang X, Cai W, Li C, Wei T, Zhang L, Yang M, Liu Q, Ye G, Cheng P, Dai X and Li BA*., 2010
The role of Pygopus 2 in rat glioma cell growth., Chen YY, Li BA*, Wang HD, Liu XY, Tan GW, Ma YH, Shen SH, Zhu HW, Wang ZX., 2011
Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth., Wang ZX, Chen YY, Li BA*, Tan GW, Liu XY, Shen SH, Zhu HW, Wang HD., 2010
Cytokeratin expression during mouse embryonic and early postnatal mammary gland development., Sun P, Yuan Y, Li A, Li B, Dai X., 2010
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation., Gu B, Sun P, Yuan Y, Moraes RC, Li A, Teng A, Agrawal A, Rhéaume C, Bilanchone V, Veltmaat JM, Takemaru K, Millar S, Lee EY, Lewis MT, and Li BA*, Dai X*., 2009
Nuclear regulator Pygo2 controls spermiogenesis and histone H3 acetylation., Nair M, Nagamori I, Sun P, Mishra DP, Rhéaume C, Li B, Sassone-Corsi P, Dai X., 2008
Analysis of mPygo2 mutant mice suggests a requirement for mesenchymal Wnt signaling in pancreatic growth and differentiation., Jonckheere N, Mayes E, Shih HP, Li B, Lioubinski O, Dai X, Sander M., 2008
Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2., Li B*, Teng A, Bilanchone V, Munguia JE, Hu M, Jessen S, Piccolo S, Waterman ML, Dai X., 2007
Abnormal expression, highly efficient detection and novel truncations of midkine in human tumors, cancers and cell lines., Tao P, Xu D, Lin S, Ouyang GL, Chang Y, Chen Q, Yuan Y, Zhuo X, Luo Q, Li J, Li B, Ruan L, Li Q, Li Z., 2007
1'S-1'-Acetoxychavicol acetate (ACA) isolated from Alpinia galanga inhibits human immunodeficiency virus type 1 (HIV-1) by blocking Rev transport., Ye Y, Li B*., 2006
Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription., Nair M, Teng A, Bilanchone V, Agrawal A, Li B, Dai X., 2006
The mouse Ovol2 gene is required for cranial neural tube development., Mackay DR, Hu M, Li B, Rheaume C, Dai X., 2006
Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression., Li B*., Nair, M., Mackay, DR., Bilanchone, V., Hu, M., Fallahi, M., Song, H., Dai, Q., Cohen, PE., Dai, X., 2005
Negative regulation of hepatocellular carcinoma cell growth by signal regulatory protein alpha1., Yan, HX., Wang, HY., Zhang, R., Chen, L., Li B., Liu, SQ., Cao, HF., Qiu, XH., Shan, YF., Yan, ZH., Wu, HP., Tan, YX., Wu, MC., 2004
Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component., Li B*., Mackay, DR., Ma, J., Dai, X., 2004
Ovol2, a Mammalian Homolog of Drosophila ovo: Gene Structure, Chromosomal Mapping, and Aberrant Expression in Blind-Sterile Mice., Li B*., Dai, Q., Li, L., Nair, M., Mackey, D., Dai, X., 2002
The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiation., Li B*., Mackey, DR, Dai, Q., Li, TW., Nair M., Fallahi, M., Schonbaum, CP., Fantes, J., Mahowald, AP., Waterman, ML., Fuchs, E., Dai, X., 2002
