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Shuyong Lin
Medical School
Xiamen University
Fujian
Language: Chinese, English
Nutrition Sensing
Key Proteins
Signaling Pathways
Physiological Conditions
Pathological Conditions
Aida
Axin1
P53
Gsk3-Tip60-Ulk
Metabolic Diseases
Areas of Focus
- Regulation and mechanism of key proteins and signaling pathways in nutrition sensing under physiological and pathological conditions
Work Experience
- 2018~Present - Xiamen University, School of Life Sciences - Professor
- 2012~2018 - Xiamen University, School of Life Sciences - Associate Professor
- 2009~2012 - Xiamen University, School of Life Sciences - Assistant Professor
Academic Background & Achievements
- 2006~2009 Doctorate: Xiamen University, School of Life Sciences
- 2003~2006 Doctorate: Hong Kong University of Science and Technology, Department of Biochemistry
- 1999~2003 Bachelor's: Xiamen University, School of Life Sciences
Publications
- Carbohydrates: Not All that Bad?, Lin SY, Zhang CS, Lin SC, 2018
- Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate, Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC, 2018
- AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity, Luo H, Jiang M, Lian G, Liu Q, Shi M, Li TY, Song L, Ye J, He Y, Yao L, Zhang C, Lin ZZ, Zhang CS, Zhao TJ, Jia WP, Li P, Lin SY, Lin SC, 2018
- Liver-specific deficiency of unc-51 like kinase 1 and 2 protects mice from acetaminophen-induced liver injury, Sun Y, Li TY, Song L, Zhang C, Li J, Lin ZZ, Lin SC, Lin SY, 2018
- ULK1/2 Constitute a Bifurcate Node Controlling Glucose Metabolic Fluxes in Addition to Autophagy, Li TY, Sun Y, Liang Y, Liu Q, Shi Y, Zhang CS, Zhang C, Song L, Zhang P, Zhang X, Li X, Chen T, Huang HY, He X, Wang Y, Wu YQ, Chen S, Jiang M, Chen C, Xie C, Yang JY, Lin Y, Zhao S, Ye Z, Lin SY, Chiu DT, Lin SC, 2016
- Structure and mechanism of the unique C2 domain of Aida, Zheng LS, Liu YT, Chen L, Wang Y, Rui YN, Huang HZ, Lin SY, Wang J, Wang ZX, Lin SC, Wu JW, 2014
- Mechanism and physiological significance of growth factor-related autophagy, Li TY, Lin SY, Lin SC, 2013
- PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation, Ruan K, Ye F, Li C, Liou YC, Lin SC, Lin SY, 2012
- Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy, Lin SY, Li TY, Liu Q, Zhang C, Li X, Chen Y, Zhang SM, Lian G, Liu Q, Ruan K, Wang Z, Zhang CS, Chien KY, Wu J, Li Q, Han J, Lin SC, 2012
- GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy, Lin SY, Li TY, Liu Q, Zhang C, Li X, Chen Y, Zhang SM, Lian G, Liu Q, Ruan K, Wang Z, Zhang CS, Chien KY, Wu J, Li Q, Han J, Lin SC, 2012
- Axin determines cell fate by controlling the p53 activation threshold after DNA damage, Li Q, Lin S, Wang X, Lian G, Lu Z, Guo H, Ruan K, Wang Y, Ye Z, Han J, Lin SC, 2009
- CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5, Lin S, Wang J, Ye Z, Ip NY, Lin SC, 2008
- A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida, Rui Y, Xu Z, Xiong B, Cao Y, Lin S, Zhang M, Chan SC, Luo W, Han Y, Lu Z, Ye Z, Zhou HM, Han J, Meng A, Lin SC, 2007
- Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation, Rui Y, Xu Z, Lin S, Li Q, Rui H, Luo W, Zhou HM, Cheung PY, Wu Z, Ye Z, Li P, Han J, Lin SC, 2004
Awards
- Fujian Province Special Support Talent 'Double Hundred Plan' Young Top-notch Innovative Talent (2016)
- National Excellent Young Scientist Fund Recipient (2018)
