Professor | Huan Liu | Asia Growth Partners

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Name	Huan Liu
Contact Information	huanliu@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Huan Liu

Contact Information

huanliu@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2001-2005 Bachelor's: Nanjing Agricultural University, Biotechnology 2005-2008 Master's: Nanjing Agricultural University, Microbiology 2008-2011 Ph.D.: Kunming Institute of Zoology, Chinese Academy of Sciences
Work Experience	2011-2012 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher 2012-2017 - MD Anderson Cancer Center, USA - Postdoctoral Fellow 2017-2020 - MD Anderson Cancer Center, USA - Lecturer 2020 - Cornell University Houston Methodist Hospital Cancer Center, USA - Research Scientist 2021-present - Xiamen University School of Medicine - Professor
Awards	National High-Level Young Talent (2022) Fujian Outstanding Youth Fund Recipient (2022) Minjiang Scholar Distinguished Professor (2021)

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2001-2005 Bachelor's: Nanjing Agricultural University, Biotechnology
2005-2008 Master's: Nanjing Agricultural University, Microbiology
2008-2011 Ph.D.: Kunming Institute of Zoology, Chinese Academy of Sciences

Work Experience

2011-2012 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
2012-2017 - MD Anderson Cancer Center, USA - Postdoctoral Fellow
2017-2020 - MD Anderson Cancer Center, USA - Lecturer
2020 - Cornell University Houston Methodist Hospital Cancer Center, USA - Research Scientist
2021-present - Xiamen University School of Medicine - Professor

Awards

National High-Level Young Talent (2022)
Fujian Outstanding Youth Fund Recipient (2022)
Minjiang Scholar Distinguished Professor (2021)

Areas of Focus	Pathogenesis and targeted therapy of multiple myeloma Feedback remodeling of bone marrow microenvironment on myeloma cells
Publications	m6A reader hnRNPA2B1 drives multiple myeloma osteolytic bone disease, Rui Liu, Yuping Zhong, Rui Chen, Chengchao Chu, Gang Liu, Yong Zhou, Yazhu Huang, Zhihong Fang and Huan Liu, 2022 Osteocyte CIITA aggravates osteolytic bone lesions in myeloma, Huan Liu, Jin He, Rozita Bagheri-Yarmand, Zongwei Li, Rui Liu, Zhiming Wang, Duc-hiep Bach, Yung-hsing Huang, Pei Lin, Theresa Guise, Robert F. Gagel, and Jing Yang, 2022 Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance, Zhiming Wang, Jin He, Duc-Hiep Bach, Yung-Hsing Huang, Zongwei Li, Huan Liu, Pei Lin, Jing Yang, 2022 Bacterial infections exacerbate myeloma bone disease, Rui Liu, Yuping Zhong, Rui Chen, Shiyi Chen, Yazhu Huang, Huan Liu, 2022 Promotion of bone lesions through the myeloma integrin α6-mediated osteolytic signaling, Huan Liu, Zhiming Wang, Jin He, Zongwei Li, Jerry Y. Gao, Rui Liu, Pei Lin, and Jing Yang, 2021 Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma, Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang, 2021 TAS-102 has a tumoricidal activity in multiple myeloma, Guoli Li, Huan Liu, Jin He, Zongwei Li, Zhiming Wang, Shan Zhou, Guopei Zheng, Zhimin He, Jing Yang, 2020 Myeloma cells shift osteoblastogenesis to adipogenesis by inhibiting the ubiquitin ligase MURF1 in mesenchymal stem cells, Zhiqiang Liu, Huan Liu, Jin He, Jingda Xu, Sheeba K. Thomas, Elisabet E Manasanch, Donna Weber, Qiang Tong, Jing Yang, 2020 Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease, Huan Liu, Jin He, Su Pin Koh, Yuping Zhong, Zhiqiang Liu, Zhiqiang Wang, Yujin Zhang, Zongwei Li, Bjorn T. Tam, Pei Lin, Min Xiao, Ken H. Young, Behrang Amini, Michael W. Starbuck, Hans C. Lee, Nora M. Navone, Richard E. Davis, Qiang Tong, P. Leif Bergsagel, Jian Hou, Qing Yi, Robert Z. Orlowski, Robert F. Gagel, Jing Yang, 2019 Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma, Huan Liu, Zhiqiang Liu, Juan Du, Jin He, Pei Lin, Behrang Amini, Michael W. Starbuck, Nora Novane, Jatin J. Shah, Richard E. Davis, Jian Hou, Robert F. Gagel, Jing Yang, 2016 C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis, Jing Yang, Zhiqiang Liu, Huan Liu, Jin He, Jianling Yang, Pei Lin, Qiang Wang, Juan Du, Wencai Ma, Zheng Yin, Eric Davis, Robert Z. Orlowski, Jian Hou, Qing Yi, 2017

Areas of Focus

Pathogenesis and targeted therapy of multiple myeloma
Feedback remodeling of bone marrow microenvironment on myeloma cells

Publications

m6A reader hnRNPA2B1 drives multiple myeloma osteolytic bone disease, Rui Liu, Yuping Zhong, Rui Chen, Chengchao Chu, Gang Liu, Yong Zhou, Yazhu Huang, Zhihong Fang and Huan Liu, 2022
Osteocyte CIITA aggravates osteolytic bone lesions in myeloma, Huan Liu, Jin He, Rozita Bagheri-Yarmand, Zongwei Li, Rui Liu, Zhiming Wang, Duc-hiep Bach, Yung-hsing Huang, Pei Lin, Theresa Guise, Robert F. Gagel, and Jing Yang, 2022
Induction of m6A methylation in adipocyte exosomal LncRNAs mediates myeloma drug resistance, Zhiming Wang, Jin He, Duc-Hiep Bach, Yung-Hsing Huang, Zongwei Li, Huan Liu, Pei Lin, Jing Yang, 2022
Bacterial infections exacerbate myeloma bone disease, Rui Liu, Yuping Zhong, Rui Chen, Shiyi Chen, Yazhu Huang, Huan Liu, 2022
Promotion of bone lesions through the myeloma integrin α6-mediated osteolytic signaling, Huan Liu, Zhiming Wang, Jin He, Zongwei Li, Jerry Y. Gao, Rui Liu, Pei Lin, and Jing Yang, 2021
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma, Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang, 2021
TAS-102 has a tumoricidal activity in multiple myeloma, Guoli Li, Huan Liu, Jin He, Zongwei Li, Zhiming Wang, Shan Zhou, Guopei Zheng, Zhimin He, Jing Yang, 2020
Myeloma cells shift osteoblastogenesis to adipogenesis by inhibiting the ubiquitin ligase MURF1 in mesenchymal stem cells, Zhiqiang Liu, Huan Liu, Jin He, Jingda Xu, Sheeba K. Thomas, Elisabet E Manasanch, Donna Weber, Qiang Tong, Jing Yang, 2020
Reprogrammed marrow adipocytes contribute to myeloma-induced bone disease, Huan Liu, Jin He, Su Pin Koh, Yuping Zhong, Zhiqiang Liu, Zhiqiang Wang, Yujin Zhang, Zongwei Li, Bjorn T. Tam, Pei Lin, Min Xiao, Ken H. Young, Behrang Amini, Michael W. Starbuck, Hans C. Lee, Nora M. Navone, Richard E. Davis, Qiang Tong, P. Leif Bergsagel, Jian Hou, Qing Yi, Robert Z. Orlowski, Robert F. Gagel, Jing Yang, 2019
Thymidine phosphorylase exerts complex effects on bone resorption and formation in myeloma, Huan Liu, Zhiqiang Liu, Juan Du, Jin He, Pei Lin, Behrang Amini, Michael W. Starbuck, Nora Novane, Jatin J. Shah, Richard E. Davis, Jian Hou, Robert F. Gagel, Jing Yang, 2016
C-reactive protein promotes bone destruction in human myeloma through the CD32-p38 MAPK-Twist axis, Jing Yang, Zhiqiang Liu, Huan Liu, Jin He, Jianling Yang, Pei Lin, Qiang Wang, Juan Du, Wencai Ma, Zheng Yin, Eric Davis, Robert Z. Orlowski, Jian Hou, Qing Yi, 2017

Multiple Myeloma Pathogenesis Targeted Therapy Bone Marrow Microenvironment Feedback Remodeling Cancer Immunology Osteolytic Therapy

Linrong Lu - Zhejiang University

Jimin Shao - Zhejiang University

Pengxu Qian - Zhejiang University

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