1992-1996 Bachelor of Science: China Agricultural University
1996-2001 Doctor of Science: China Agricultural University (Supervisor: Professor Guoliang Xia)
2000-2001 Exchange Student: Tokyo University of Agriculture and Technology (Supervisor: Professor Kazuyoshi Tagaya)
2001-2002 - University of Kansas Medical Center - Postdoctoral Researcher (Collaborator: Professor SK Dey)
2002-2004 - Vanderbilt University Medical Center - Postdoctoral Researcher (Collaborator: Professor SK Dey)
2004-2008 - Vanderbilt University Medical Center - Research Assistant Professor, Assistant Professor
2008-2016 - Institute of Zoology, Chinese Academy of Sciences - Researcher
2016-present - Xiamen University School of Medicine - Distinguished Professor
China Youth Science and Technology Award
Chinese Academy of Sciences Young Scientist Award
Zhu Li Yuehua Excellent Teacher Award of the Chinese Academy of Sciences
First Prize of National Maternal and Child Health Science and Technology Award in Natural Science
Xiamen City Outstanding Youth Award
Research
Molecular mechanisms of blastocyst activation Molecular regulatory network of endometrial receptivity and decidualization Molecular basis of placental development and function
P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation., Tang Y, Qiu J, Tang Z, Li G, Gu M, Wang Y, Bao H, Deng W, Lu Z, Otsu K, Wang Z, Wang H, Kong S., 2022
Menin directs regionalized decidual transformation through epigenetically setting PTX3 to balance FGF and BMP signaling., Liu M, Deng W, Tang L, Liu M, Bao H, Guo C, Zhang C, Lu J, Wang H, Lu Z, Kong S., 2022
SOX4 facilitates PGR protein stability and FOXO1 expression conducive for human endometrial decidualization., Huang P, Deng W, Bao H, Lin Z, Liu M, Wu J, Zhou X, Qiao M, Yang Y, Cai H, Rao F, Chen J, Chen D, Lu J, Wang H, Qin A, Kong S., 2022
Shp2 in uterine stromal cells critically regulates on time embryo implantation and stromal decidualization by multiple pathways during early pregnancy., Cheng J, Liang J, Li Y, Gao X, Ji M, Liu M, Tian Y, Feng G, Deng W, Wang H, Kong S, Lu Z., 2022
Single-cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion., Du L, Deng W, Zeng S, Xu P, Huang L, Liang Y, Wang Y, Xu H, Tang J, Bi S, Zhang L, Li Y, Ren L, Lin L, Deng W, Liu M, Chen J, Wang H, Chen D., 2021
Sequential activation of uterine epithelial IGF1R by stromal IGF1 and embryonic IGF2 directs normal uterine preparation for embryo implantation., Zhou C, Lv M, Wang P, Guo C, Ni Z, Bao H, Tang Y, Cai H, Lu J, Deng W, Yang X, Xia G, Wang H, Wang C, Kong S., 2021
Uterine Notch2 facilitates pregnancy recognition and corpus luteum maintenance via upregulating decidual Prl8a2., Bao H, Sun Y, Yang N, Deng N, Ni Z, Tang Y, Li G, Du L, Wang YL, Chen D, Wang H, Kong S., 2021
Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2., Bao H, Liu D, Xu Y, Sun Y, Mu C, Yu Y, Wang C, Han Q, Liu S, Cai H, Liu F, Kong S, Deng W, Cao B, Wang H, Wang Q, Lu J., 2020
Blastocyst activation engenders transcriptome reprogram affecting X-chromosome reactivation and inflammatory trigger of implantation., He B, Zhang H, Wang J, Liu M, Sun Y, Guo C, Lu J, Wang H, Kong S., 2019
Epigenetic control of embryo-uterine crosstalk at peri-implantation., Kong S, Zhou C, Bao H, Ni Z, Liu M, He B, Huang L, Sun Y, Wang H, Lu J., 2019
Spatiotemporal coordination of trophoblast and allantoic Rbpj signaling directs normal placental morphogenesis., Lu J, Wu W, Xin Q, Zhou C, Wang J, Ni Z, Liu D, Xu Y, Yu Y, Yang N, Sun Y, He B, Kong S, Wang S, Wang C, Wang H., 2019
Polycomb subunit BMI1 determines uterine progesterone responsiveness essential for normal embryo implantation., Xin Q, Kong S, Yan J, Qiu J, He B, Zhou C, Ni Z, Bao H, Huang L, Lu J, Xia G, Liu X, Chen Z, Wang C, Wang H., 2018
PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice., Cui T, He B, Kong S, Zhou C, Zhang H, Ni Z, Bao H, Qiu J, Xin Q, Reinberg D, Lydon JP, Lu J, Wang H., 2017
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase., Ran H, Kong S, Zhang S, Cheng J, Zhou C, He B, Xin Q, Lydon JP, DeMayo FJ, Feng GS, Xia G, Lu Z, Wang C, Wang H., 2017
Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice., Tu Z, Wang Q, Cui T, Wang J, Ran H, Bao H, Lu J, Wang B, Lydon JP, DeMayo F, Zhang S, Kong S, Wu X, Wang H., 2016
NEDD8-mediated neddylation is required for human endometrial stromal proliferation and decidualization., Liao Y, Jiang Y, He H, Ni H, Tu Z, Zhang S, Wang B, Lou J, Quan S, Wang H., 2015
Uterine Rbpj is required for embryo-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms., Zhang S, Kong S, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang HM, Wang YL, Li B, Chen Q, Duan E, Wang H., 2014
A positive feedback loop involving gcm1 and fzd5 directs chorionic branching morphogenesis in the placenta., Lu J, Zhang S, Nakano H, Simmons DG, Wang S, Kong S, Wang Q, Shen L, Tu Z, Wang W, Wang B, Wang HM, Wang Y, van Es JH, Clevers H, Leone G, Cross JC, Wang H., 2013
Physiological and molecular determinants of embryo implantation., Zhang S, Lin H, Kong S, Wang S, Wang HM, Wang H, Armant DR., 2013
Uterine disorders and pregnancy complications: insights from mouse models., Lim H, Wang H., 2010
