Professor | Nengming Xiao | Asia Growth Partners

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Name	Nengming Xiao
Contact Information	nnengming@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Nengming Xiao

Contact Information

nnengming@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2000 - Bachelor of Science: Beijing Normal University 2006 - Doctor of Science: Peking University
Work Experience	2006-08 to 2009-04 - The Scripps Research Institute - Postdoctoral Research 2009-05 to 2010-05 - Cleveland Clinic - Postdoctoral Research 2010-06 to 2014-09 - La Jolla Institute for Allergy and Immunology - Postdoctoral Research 2014-12 to Present - Xiamen University - Professor

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2000 - Bachelor of Science: Beijing Normal University
2006 - Doctor of Science: Peking University

Work Experience

2006-08 to 2009-04 - The Scripps Research Institute - Postdoctoral Research
2009-05 to 2010-05 - Cleveland Clinic - Postdoctoral Research
2010-06 to 2014-09 - La Jolla Institute for Allergy and Immunology - Postdoctoral Research
2014-12 to Present - Xiamen University - Professor

Areas of Focus	Regulatory mechanisms of innate and adaptive immunity
Publications	In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation., Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME, 2014 TLR signaling controls lethal encephalitis in WNV-infected brain., Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE, 2014 The E3 ubiquitin ligase Itch is required for the differentiation of T follicular helper cells., Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC, 2014 MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases., Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Harding CV, Hise AG, Hazen SL, Defranco AL, Fox PL, Morton RE, Dicorleto PE, Febbraio M, Nagy LE, Smith JD, Wang JA, Li X, 2014 Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10., Burkart C, Arimoto KI, Tang T, Cong X, Xiao N, Liu YC, Kotenko SV, Ellies LG, Zhang DE, 2013 ENU-induced phenovariance in mice: inferences from 587 mutations., Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, Du X, Eidenschenk C, Georgel P, Hoebe K, Huang H, Jiang Z, Krebs P, La Vine D, Li X, Lyon S, Moresco EM, Murray AR, Popkin DL, Rutschmann S, Siggs OM, Smart NG, Sun L, Tabeta K, Tomisato W, Webster V, Won S, Xia Y, Xiao N, Beutler B, 2012 β-TrCP-Mediated IRAK1 Degradation Releases TAK1-TRAF6 from the Membrane to the Cytosol for TAK1-Dependent NF-κB Activation., Cui W, Xiao N, Xiao H, Zhou H, Yu M, Gu J, Li X, 2012 iRhom2 is required for the secretion of mouse TNFα., Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B, 2012 The Tpl2 mutation sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease., Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B, 2009 Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2., Jimenez-Dalmaroni MJ, Xiao N, Corper AL, Verdino P, Ainge GD, Larsen DS, Painter GF, Rudd PM, Dwek RA, Hoebe K, Beutler B, Wilson IA, 2009 Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response., Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B, 2009 Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria., Xu L, Xiao N, Liu F, Ren H, Gu J, 2009

Areas of Focus

Regulatory mechanisms of innate and adaptive immunity

Publications

In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation., Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME, 2014
TLR signaling controls lethal encephalitis in WNV-infected brain., Sabouri AH, Marcondes MC, Flynn C, Berger M, Xiao N, Fox HS, Sarvetnick NE, 2014
The E3 ubiquitin ligase Itch is required for the differentiation of T follicular helper cells., Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC, 2014
MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases., Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Harding CV, Hise AG, Hazen SL, Defranco AL, Fox PL, Morton RE, Dicorleto PE, Febbraio M, Nagy LE, Smith JD, Wang JA, Li X, 2014
Usp18 deficient mammary epithelial cells create an antitumour environment driven by hypersensitivity to IFN-λ and elevated secretion of Cxcl10., Burkart C, Arimoto KI, Tang T, Cong X, Xiao N, Liu YC, Kotenko SV, Ellies LG, Zhang DE, 2013
ENU-induced phenovariance in mice: inferences from 587 mutations., Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, Du X, Eidenschenk C, Georgel P, Hoebe K, Huang H, Jiang Z, Krebs P, La Vine D, Li X, Lyon S, Moresco EM, Murray AR, Popkin DL, Rutschmann S, Siggs OM, Smart NG, Sun L, Tabeta K, Tomisato W, Webster V, Won S, Xia Y, Xiao N, Beutler B, 2012
β-TrCP-Mediated IRAK1 Degradation Releases TAK1-TRAF6 from the Membrane to the Cytosol for TAK1-Dependent NF-κB Activation., Cui W, Xiao N, Xiao H, Zhou H, Yu M, Gu J, Li X, 2012
iRhom2 is required for the secretion of mouse TNFα., Siggs OM, Xiao N, Wang Y, Shi H, Tomisato W, Li X, Xia Y, Beutler B, 2012
The Tpl2 mutation sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease., Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B, 2009
Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2., Jimenez-Dalmaroni MJ, Xiao N, Corper AL, Verdino P, Ainge GD, Larsen DS, Painter GF, Rudd PM, Dwek RA, Hoebe K, Beutler B, Wilson IA, 2009
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response., Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B, 2009
Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria., Xu L, Xiao N, Liu F, Ren H, Gu J, 2009

Immunity Innate Adaptive Regulation Mechanisms T Cells B Cells Germinal Center Tfh Bcl-6

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Yushi Yao - Zhejiang University

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