1983.09–1987.07 Bachelor: Liaoning Normal University, Biology
1987.09–1990.07 Master: Lanzhou University Medical School, Histology and Embryology
2000.09–2006.12 PhD: Xiamen University, Zoology
1990.07-1997.07 - Lanzhou University Medical School - Assistant Lecturer in Histology and Embryology
1993.08-1998.07 - Lanzhou University Medical School - Lecturer in Histology and Embryology
1998.08-1998.12 - Lanzhou University Medical School - Associate Professor in Histology and Embryology
1998.12-2008.07 - Xiamen University Medical School - Associate Professor in Basic Medicine
2008.08-present - Xiamen University Medical School - Professor in Basic Medicine
1999: Gansu Province Science and Technology Progress Award
2006: Xiamen University Excellent Course in Histology and Embryology
2009: Fujian Province Excellent Course in Histology and Embryology
2011: Xiamen University First 'Most Popular Female Teacher' Nomination
2014: Xiamen City Science and Technology Progress Second Prize
Research
Regulatory mechanisms of phospholipase C and related signaling molecules in cellular life activities
Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma., Bingchang Zhang, Fen Wang, Lianzhi Dai, Heguo Cai, Yanyan Zhan, Gang Song, Tianhui Hu, Chun Xia (corresponding), Bing Zhang (corresponding), 2016
Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1., Cui X, Wang S, Cai H, Lin Y, Zheng X, Zhang B (corresponding), Xia C (corresponding), 2016
DAG/PKCδ and IP3/Ca(2+)/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway., Lianzhi Dai, Luhua Zhuang, Bingchang Zhang, Fen Wang, Xiaolei Chen, Chun Xia (corresponding), Bing Zhang (corresponding), 2015
The Involvement of Mutual Inhibition of ERK and mTOR in PLCγ1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes., Zejun Liu, Heguo Cai, Xinpeng Zheng, Bing Zhang (corresponding), Chun Xia (corresponding), 2015
Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells., Tingting Yi, Luhua Zhuang, Gang Song, Guideng Li, Bing Zhang (corresponding), Tianhui Hu, 2015
Metastasis of human gastric adenocarcinoma partly depends on phosphoinositide-specific phospholipase γ1 expression., Luhua Zhuang, Bingchang Zhang, Guoqing Zeng, Lianzhi Dai, Hongliu Qian, Tianhui Hu, Gang Song, Bing Zhang (corresponding), Chun Xia (corresponding), 2014
Disruption of phosphoinositide-specific phospholipases Cγ1 contributes to extracellular matrix synthesis of human osteoarthritis chondrocytes., Zeng G, Cui X, Liu Z, Zhao H, Zheng X, Zhang B (corresponding), Xia C (corresponding), 2014
Berberine ameliorates cartilage degeneration in interleukin-1β-stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling., Zhao H, Zhang T, Xia C (corresponding), Shi L, Wang S, Zheng X, Hu T, Zhang B (corresponding), 2014
12-O-tetradecanoylphorbol-1,3-acetate-induced degradation of protein kinase B via ubiquitin-proteasomal pathway depends on its Ser473 phosphorylation in gastric cancer cells., Zhang B, Xia C (corresponding), 2013
Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes., Chen Q, Zhang B (corresponding), Yi T, Xia C (corresponding), 2012
Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis., Zheng X, Xia C (corresponding), Chen Z, Huang J, Gao F, Li G, Zhang B (corresponding), 2012
17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/AKT pathway., Huang JG, Xia C (corresponding), Zheng XP, Yi TT, Wang XY, Song G, Zhang B (corresponding), 2011
12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Calpha during gastric cancer cell apoptosis., Zhang B, Xia C (corresponding), 2010
The expression of protein kinase B in gastric cancer cell apoptosis induced by 12-O-tetradecanoylphorbol-1, 3-acetate., Zhang B, Xia C (corresponding), 2009
Roles of PLC-γ2 and PKCα in TPA-induced apoptosis of gastric cancer cells., Bing Zhang, Qiao Wu (corresponding), Xiao-Feng Ye, Su Liu, Xiao-Feng Lin, Mu-Chuan Chen, 2003
