Professor | Yongyou Zhang | Asia Growth Partners

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Name	Yongyou Zhang
Contact Information	nyongyouzhang@xmu.edu.cn
Language ability	English, Chinese
Province	Fujian

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Name

Yongyou Zhang

Contact Information

nyongyouzhang@xmu.edu.cn

Language ability

English, Chinese

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2000 - Bachelor's Degree: Xiamen University 2003 - Master's Degree: Xiamen University 2008 - Ph.D.: Texas A&M University 2016 - Selected as 'Minjiang Scholar' Distinguished Professor
Work Experience	2009-2015 - Case Western Reserve University, School of Medicine - Postdoctoral Researcher 2015-2016 - Case Western Reserve University, School of Medicine - Research Scientist 2016-present - Xiamen University, School of Life Sciences - Professor, Research Group Leader
Awards	2016: Selected as 'Minjiang Scholar' Distinguished Professor

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2000 - Bachelor's Degree: Xiamen University
2003 - Master's Degree: Xiamen University
2008 - Ph.D.: Texas A&M University
2016 - Selected as 'Minjiang Scholar' Distinguished Professor

Work Experience

2009-2015 - Case Western Reserve University, School of Medicine - Postdoctoral Researcher
2015-2016 - Case Western Reserve University, School of Medicine - Research Scientist
2016-present - Xiamen University, School of Life Sciences - Professor, Research Group Leader

Awards

2016: Selected as 'Minjiang Scholar' Distinguished Professor

Areas of Focus	Tumor Metabolism and Tissue Regeneration
Publications	Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration, Y. Zhang, A. Desai, S. Yang, K. Bae, M. Antczak, S. Fink, S. Tiwari, et al., 2015 Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs, S. Fink, D. Dawson, Y. Zhang, A. Kresak, E. Lawrence, P. Yang, Y. Chen, J. Barnholtz, J. Willis, L. Kopelovich, S. Markowitz, 2014 FGFR1 is essential for prostate cancer progression and metastasis, F. Yang, Y. Zhang, S.J. Ressler, M.M. Ittmann, G.E. Ayala, T.D. Dang, F. Wang, D.R. Rowley, 2013 FRS2a is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts, Lin, X, Y. Zhang, L. Liu, W.L. McKeehan, Y. Shen, S. Song, and F. Wang, 2011 The Mst1 and Mst2 kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yap overabundance, D. Zhou, Y. Zhang*, H. Wu, E. Barry, Y. Yi, E. Lawrence, D. Dawson, J.E. Willis, S.D. Markowitz, F.D. Camargo and J. Avruch, 2011 Role of epithelial cell fibroblast growth factor receptor substrate 2a in prostate development, regeneration and tumorigenesis, Y. Zhang, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan, N.M. Greenberg, and F. Wang, 2008 FGFR1 tyrosine phosphorylation regulates binding of FRS2alpha but not FRS2beta to the receptor, Y. Zhang, W.L. McKeehan, Y. Lin, J. Zhang, and F. Wang, 2008 Frs2a deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis, J. Zhang, Y. Lin, Y. Zhang, Y. Lan, C. Lin, A.M. Moon, R.J. Schwartz, J.M. Martin, and F. Wang, 2008 Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial to mesenchymal transition, V. D. Acevedo, R. D. Gangula, R. Li, Y. Zhang, F. Wang, G.E. Ayala, L.E. Peterson, M. Ittmann, and D.M. Spencer, 2007 Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis, Y. Lin, G. Liu, Y. Zhang, Y. Hu, K. Yu, C. Lin, K. McKeehan, J. Xuan, D. Ornitz, M.M. Shen, N.M. Greenberg, W.L. McKeehan, F. Wang, 2007 Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2, Y. Zhang, Y. Lin, C. Bowles, and F. Wang, 2004 Real-time PCR genotyping using displacing probes, J. Cheng, Y. Zhang and Q. Li, 2004

Areas of Focus

Tumor Metabolism and Tissue Regeneration

Publications

Inhibition of the Prostaglandin Degrading Enzyme 15-PGDH Potentiates Tissue Regeneration, Y. Zhang*, A. Desai*, S. Yan*g, K. Bae*, M. Antczak*, S. Fink*, S. Tiwari*, et al., 2015
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs, S. Fink, D. Dawson, Y. Zhang, A. Kresak, E. Lawrence, P. Yang, Y. Chen, J. Barnholtz, J. Willis, L. Kopelovich, S. Markowitz, 2014
FGFR1 is essential for prostate cancer progression and metastasis, F. Yang, Y. Zhang, S.J. Ressler, M.M. Ittmann, G.E. Ayala, T.D. Dang, F. Wang, D.R. Rowley, 2013
FRS2a is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts, Lin, X, Y. Zhang, L. Liu, W.L. McKeehan, Y. Shen, S. Song, and F. Wang, 2011
The Mst1 and Mst2 kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yap overabundance, D. Zhou*, Y. Zhang*, H. Wu, E. Barry, Y. Yi, E. Lawrence, D. Dawson, J.E. Willis, S.D. Markowitz, F.D. Camargo and J. Avruch, 2011
Role of epithelial cell fibroblast growth factor receptor substrate 2a in prostate development, regeneration and tumorigenesis, Y. Zhang, J. Zhang, Y. Lin, Y. Lan, C. Lin, J.W. Xuan, M.M. Shen, W.L. McKeehan, N.M. Greenberg, and F. Wang, 2008
FGFR1 tyrosine phosphorylation regulates binding of FRS2alpha but not FRS2beta to the receptor, Y. Zhang, W.L. McKeehan, Y. Lin, J. Zhang, and F. Wang, 2008
Frs2a deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis, J. Zhang, Y. Lin, Y. Zhang, Y. Lan, C. Lin, A.M. Moon, R.J. Schwartz, J.M. Martin, and F. Wang, 2008
Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial to mesenchymal transition, V. D. Acevedo, R. D. Gangula, R. Li, Y. Zhang, F. Wang, G.E. Ayala, L.E. Peterson, M. Ittmann, and D.M. Spencer, 2007
Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis, Y. Lin, G. Liu, Y. Zhang, Y. Hu, K. Yu, C. Lin, K. McKeehan, J. Xuan, D. Ornitz, M.M. Shen, N.M. Greenberg, W.L. McKeehan, F. Wang, 2007
Direct cell cycle regulation by the fibroblast growth factor receptor (FGFR) kinase through phosphorylation-dependent release of Cks1 from FGFR substrate 2, Y. Zhang, Y. Lin, C. Bowles, and F. Wang, 2004
Real-time PCR genotyping using displacing probes, J. Cheng, Y. Zhang and Q. Li, 2004

Tumor Metabolism Tissue Regeneration Cell Signaling Microenvironment Gene Modification Prostaglandin Stem Cells Drug Development

Linrong Lu - Zhejiang University

Zhimin Lu - Zhejiang University

Jiang Cao - Zhejiang University

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