Upload Avatar (500 x 500)
Han Han
Medical School
Wuhan University
Hubei
Language: Chinese, English
Cell Biology
Tumor
Hippo Pathway
Phospholipid Metabolism
Trace Metals
Gene Mutation
Personalized Medicine
Cancer
Molecular Biology
Proteomics
Phospholipid
Metabolism
Disease
Cell Signaling
Biochemistry
Gene Regulation
Homeostasis
Metal Toxicity
Screening
Personalized Treatment
Genomics
Areas of Focus
- Tumor Cell Biology
- Phospholipid Metabolism and Disease
- Essential Trace Metal Homeostasis and Disease
- Pathogenic Gene Mutation Screening and Personalized Treatment
Work Experience
- 2023 - Present Professor at Basic Medical College, Wuhan University; PI at Taikang Life Medical Center
- 2020 - 2023 Associate Research Specialist, Department of Developmental and Cell Biology, University of California, Irvine
- 2016 - 2020 Postdoctoral Researcher, Department of Developmental and Cell Biology, University of California, Irvine
- 2015 - 2016 Postdoctoral Researcher, Department of Experimental Radiation Oncology, MD Anderson Cancer Center, University of Texas
Academic Background & Achievements
- 2010 - 2015 PhD in Cell Biology, College of Life Sciences, Wuhan University
- 2006 - 2010 Bachelor in Biotechnology, College of Life Sciences, Ningxia University
Publications
- A tale of two Hippo pathway modules, Han H, Wang W, 2023
- The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1, Han H, Nakaoka HJ, Hofmann L, Zhou JJ, Yu C, et al., 2022
- Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution, Chen Y*, Han H*, Seo G, Vargas RE, Yang B, et al., 2020
- Elucidation of WW domain ligand binding specificities in the Hippo pathway reveals STXBP4 as YAP inhibitor, Vargas RE*, Duong VT*, Han H*, Ta AP, Chen Y, et al., 2020
- Regulation of the Hippo pathway by phosphatidic acid-mediated lipid-protein interaction, Han H, Qi R, Zhou JJ, Ta AP, Yang B, et al., 2018
- Hippo signaling dysfunction induces cancer cell addiction to YAP, Han H, Yang B, Nakaoka HJ, Yang J, Zhao Y, et al., 2018
- LncRNA wires up Hippo and hedgehog signaling to reprogram glucose metabolism, Zheng X*, Han H*, Liu G*, Ma Y, Pan R, et al., 2017
- Angiomotin-like 2 interacts with and negatively regulates AKT, Han H, Yang B, Wang W, 2017
- Proteomic analysis of the human tankyrase protein interaction network reveals its role in pexophagy, Li X*, Han H*, Zhou MT*, Yang B, Ta AP, et al., 2017
- microRNA-129-5p, a c-Myc negative target, affects hepatocellular carcinoma progression by blocking the Warburg effect, Han H, Li W, Shen H, Zhang J, Zhu Y, et al., 2016
Awards
- National Talent Project (2022)
- Key Contact Expert of Hubei Province (2021)
- Dean's Award for Excellence in Research, University of California, Irvine (2018)
- Wuhan University Academic Innovation Award (2016)
