2012 Chinese National Excellent Doctoral Dissertation nomination
2012 Excellent Doctoral Dissertation Award, Tianjin city, China
2011 ASBMR Young Investigator Award, ASBMR annual meeting
2011 Young Investigator Award, 9th International Conference on Bone and Mineral Research & 11th International Osteoporosis Symposium
2010 Excellent PhD Graduate Award, Tianjin Medical University
Research
Molecular mechanisms of osteoclast and osteoblast formation and differentiation Molecular mechanisms of bone remodeling Cancer bone metastasis Molecular mechanisms of bone angiogenesis
Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone, Yu S., Franceschi R.T., Luo M., Fan J., Jiang D., Cao H., Kwon T.G., Lai Y., Zhang J., Patrene K., Hankenson K., Roodman G.D., and Xiao G., 2009
Activating transcription factor 4 regulates osteoclast differentiation in mice, Cao H., Yu S., Yao Z., Galson D.L., Jiang Y., Zhang X., Fan J., Lu B., Guan Y., Luo M., Lai Y., Zhu Y., Kurihara N., Patrene K., Roodman G.D., and Xiao G., 2010
Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts, Yang S., Xu H., Yu S., Cao H., Fan J., Ge C., Fransceschi R.T., Dong H.H., and Xiao G., 2011
Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling, Xiao G., Cheng H., Cao H., Chen K., Tu Y., Yu S., Jiao H., Yang S., Im H.J., Chen D., Chen J., and Wu C., 2012
Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease, Teramachi J., Hiruma Y., Ishizuka S., Ishizuka H., Brown J.P., Michou L., Cao H., Galson D.L., Subler M.A., Zhou H., Dempster D.W., Windle J.J., Roodman G.D., and Kurihara N., 2013
ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment, Zhu K., Jiao H., Li S., Cao H., Galson D.L., Zhao Z., Zhao X., Lai Y., Fan J., Im H.J., Chen D., and Xiao G., 2013
Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis, Cao H., Zhu K., Qiu L., Li S., Niu H., Hao M., Yang S., Zhao Z., Lai Y., Anderson J.L., Fan J., Im H.J., Chen D., Roodman G.D., and Xiao G., 2013
Tumour necrosis factor superfamily member 15 (Tnfsf15) facilitates lymphangiogenesis via up-regulation of Vegfr3 gene expression in lymphatic endothelial cells, Qin T.T., Xu G.C., Qi J.W., Yang G.L., Zhang K., Liu H.L., Xu L.X., Xiang R., Xiao G., Cao H., Wei Y., Zhang Q.Z., and Li L.Y., 2015
Kindlin-2 controls TGF-beta signalling and Sox9 expression to regulate chondrogenesis, Wu C., Jiao H., Lai Y., Zheng W., Chen K., Qu H., Deng W., Song P., Zhu K., Cao H., Galson D.L., Fan J., Im H.J., Liu Y., Chen J., Chen D., and Xiao G., 2015
ATF4 Regulates CD4(+) T Cell Immune Responses through Metabolic Reprogramming, Yang X., Xia R., Yue C., Zhai W., Du W., Yang Q., Cao H., Chen X., Obando D., Zhu Y., Chen X., Chen J.J., Piganelli J., Jiang Y., Xiao G., Wu C., Jiang J., and Lu B., 2018
Lipoatrophy and metabolic disturbance in mice with adipose-specific deletion of kindlin-2, Gao H., Guo Y., Yan Q., Yang W., Li R., Lin S., Bai X., Liu C., Chen D., Cao H., and Xiao G., 2019
Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice, Wang Y., Yan Q., Zhao Y., Liu X., Lin S., Zhang P., Ma L., Lai Y., Bai X., Liu C., Wu C., Feng J.Q., Chen D., Cao H., and Xiao G., 2019
Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice, Cao H., Yan Q., Wang D., Lai Y., Zhou B., Zhang Q., Jin W., Lin S., Lei Y., Ma L., Guo Y., Wang Y., Wang Y., Bai X., Liu C., Feng J.Q., Wu C., Chen D., Cao X., and Xiao G., 2020
Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice, Zhu K., Lai Y., Cao H., Bai X., Liu C., Yan Q., Ma L., Chen D., Kanaporis G., Wang J., Li L., Cheng T., Wang Y., Wu C., and Xiao G., 2020
Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells, Chen S., Qin L., Wu X., Fu X., Lin S., Chen D., Xiao G., Shao Z., and Cao H., 2020
LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice, Lei Y., Fu X., Li P., Lin S., Yan Q., Lai Y., Liu X., Wang Y., Bai X., Liu C., Chen D., Cao H., Xiao G., 2020
Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice, Fu X., Zhou B., Yan Q., Tao C., Qin L., Wu X., Lin S., Chen S., Lai Y., Zou X., Shao Z., Wang M., Chen D., Jin W., Song Y., Cao H., Zhang G., and Xiao G., 2020
Kindlin-2 mediates mechanotransduction in bone by regulating expression of Sclerostin in osteocytes, Qin L., Fu X., Ma J., Lin M., Zhang P., Wang Y., Yan Q., Tao C., Liu W., Tang B., Chen D., Bai X., Cao H., Xiao G., 2021
Pinch loss ameliorates obesity, glucose intolerance and fatty liver by modulating adipocyte apoptosis in mice, Gao H., Zhong Y., Ding Z., Lin S., Hou X., Tang W., Zhou X., Zou X., Shao J., Yang F., Bai X., Liu C., Cao H., Xiao G., 2021
Kindlin-2 inhibits NLRP3 inflammasome activation in nucleus pulposus to maintain homeostasis of the intervertebral disc, Chen S., Wu X., Lai Y., Chen D., Bai X., Liu S., Wu Y., Cao H., Shao Z., Xiao G., 2022
Kindlin-2 preserves integrity of the articular cartilage to protect against osteoarthritis, Wu X., Lai Y., Chen S., Zhou C., Tao C., Fu X., Li J., Huang J., Tong W., Tian H., Shao Z., Liu C., Chen D., Bai X., Cao H., Xiao G., 2022
Kindlin-2 haploinsufficiency protects against fatty liver by targeting Foxo1 in mice, Gao H., Zhou L., Zhong Y., Ding Z., Lin S., Hou X., Zhou X., Shao J., Yang F., Zou X., Cao H., Xiao G., 2022
A novel sprayable thermosensitive hydrogel coupled with
