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Qian Chen
Medical School
Xiamen University
Fujian
Language: English, Chinese
Diabetes
Retina
Vascular
Wnt
Mirna
Pathogenesis
Therapy
Mechanism
Signaling
Disease
Areas of Focus
- Diabetic Retinopathy
- Wnt Signaling Pathway
- miRNAs in Retinal Diseases
Work Experience
- 2016-2017 - University of Oklahoma - Postdoctoral Researcher
- 2017-present - Xiamen University School of Medicine, Xiamen University Eye Institute - Associate Professor
Academic Background & Achievements
- 2003-2008 Bachelor: Wuhan University, Clinical Medicine
- 2008-2010 Master: Wuhan University, Oncology
- 2010-2016 PhD: University of Oklahoma, Physiology
Publications
- Pathological role of miR-21 in diabetic retinopathy through down-regulation of PPARα, Chen Q, Qiu FF, Zhou KL, Matlock G, Takahashi Y, Yang HF, Moran E, Ma JX, 2017
- Canonical Wnt signaling in diabetic retinopathy, Chen Q, Ma JX, 2017
- Functional differences of VLDLR splice variants in regulating Wnt signaling, Chen Q, Takahashi Y, Oka K, Ma JX, 2016
- MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization, Takahashi Y, Chen Q, Rajala, Ma JX, 2015
- MiRNA-200b down-regulates Oxidation Resistance 1 (Oxr1) expression in the retina of type 1 diabetes model, Murray AR, Chen Q, Takahashi Y, Zhou KK, Park K, Ma JX, 2013
- Therapeutic effects of PPARα agonist on experimental neovascular age-related macular degeneration, Qiu FF, Matlock GH, Chen Q, Zhou KL, Du YH, Wang X and Ma JX, 2017
- Thrombus leukocytes exhibit more endothelial cell-specific angiogenic markers than peripheral blood leukocytes do in acute coronary syndrome patients, suggesting a possibility of trans-differentiation: a comprehensive database mining study, Fu H, Vadalia N, Xue ER, Johnson C, Wang L, Yang WY, Sanchez C, Nelson J, Chen Q, Choi ET, Ma JX, Yu J, Wang H, Yang XF, 2017
- Protective and Antioxidant Effects of PPAR-α in the Ischemic Retina, Moran E, Ding LX, Wang ZX, Cheng R, Chen Q, Moore R, Takahashi Y and Ma JX, 2014
- Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction, Hu Y, Chen Y, Ding LX, He XM, Takahashi Y, Gao Y, Shen W, Cheng R, Chen Q, Qi XP, Boulton M, and Ma JX, 2013
Awards
- 2014-2016 American Heart Association Postdoctoral Fellowship: Differential Roles of VLDLR Splice Variants in Canonical Wnt Signaling Regulation
