2000-2005: Bachelor of Medicine, Lanzhou University School of Public Health
2005-2008: Master of Medicine, Lanzhou University School of Public Health
2008-2011: Doctor of Medicine, Huazhong University of Science and Technology School of Public Health
2011.09-2014.03: Postdoctoral Researcher, School of Life Sciences, Xiamen University
2014.04-present: Associate Professor, School of Medicine, Xiamen University
Research
Epigenetic mechanisms of chronic metabolic diseases induced by environmental factors
MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1, Wei J, Ding D, Wang T, Liu Q, Lin Y, 2017
Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease, Lin Y, Ding D, Huang Q, Liu Q, Lu H, Lu Y, Chi Y, Sun X, Ye G, Zhu H, Wei J, Dong S, 2017
miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis, Wang T, Hou J, Li Z, Zheng Z, Wei J, Song D, Hu T, Wu Q, Yang JY, Cai JC, 2017
MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer, Jiang C, Chen X, Alattar M, Wei J, Liu H, 2015
Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet, Wei J, Sun X, Chen Y, Li Y, Song L, Zhou Z, Xu B, Lin Y, Xu S, 2014
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma, Gao SB, Xu B, Ding LH, Zheng QL, Zhang L, Zheng QF, Li SH, Feng ZJ, Wei J, Yin ZY, Hua X, Jin GH, 2014
Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice, Luo Y, Liu Y, Liu M, Wei J, Zhang Y, Hou J, Huang W, Wang T, Li X, He Y, Ding F, Yuan L, Cai J, Zheng F, Yang JY, 2014
Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice, Wei J, Zhang Y, Luo Y, Wang Z, Bi S, Song D, Dai Y, Wang T, Qiu L, Wen L, Yuan L, Yang JY, 2014
Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells, Lin Y, Sun X, Qiu L, Wei J, Huang Q, Fang C, Ye T, Kang M, Shen H, Dong S, 2013
Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate, Lv Z, Li G, Li Y, Ying C, Chen J, Chen T, Wei J, Lin Y, Jiang Y, Wang Y, Shu B, Xu B, Xu S, 2013
Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets, Song L, Xia W, Zhou Z, Li Y, Lin Y, Wei J, Wei Z, Xu B, Shen J, Li W, Xu S, 2012
Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring, Wei Z, Song L, Wei J, Chen T, Chen J, Lin Y, Xia W, Xu B, Li X, Chen X, Li Y, Xu S, 2012
Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat, Lin Y, Wei J, Li Y, Chen J, Zhou Z, Song L, Wei Z, Lv Z, Chen X, Xia W, Xu S, 2011
Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet, Wei J, Lin Y, Li Y, Ying C, Chen J, Song L, Zhou Z, Lv Z, Xia W, Chen X, Xu S, 2011
Inflammation-like glial response in rat brain induced by prenatal PFOS exposure, Zeng HC, Zhang L, Li YY, Wang YJ, Xia W, Lin Y, Wei J, Xu SQ, 2011
MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate, Zhang L, Li YY, Zeng HC, Wei J, Wan YJ, Chen J, Xu SQ, 2011
Prenatal exposure to perfluorooctanesulfonate in rat resulted in long-lasting changes of expression of synapsins and synaptophysin, Zeng HC, Li YY, Zhang L, Wang YJ, Chen J, Xia W, Lin Y, Wei J, Lv ZQ, Li M, Xu SQ, 2011
Alterations in tumor biomarker GSTP gene methylation patterns induced by prenatal exposure to PFOS, Wan YJ, Li YY, Xia W, Chen J, Lv ZQ, Zeng HC, Zhang L, Yang WJ, Chen T, Lin Y, Wei J, Xu SQ, 2010
Electrochemical biosensor for estrogenic substance using lipid bilayers modified by Au nanoparticles, Xia W, Li Y, Wan Y, Chen T, Wei J, Lin Y, Xu S, 2010
Keywords
EpigeneticsChronic DiseasesMetabolic DisordersEnvironmental FactorsObesityInsulin ResistanceType 2 DiabetesGene RegulationMolecular MechanismsPublic Health
Area of Focus
Global Health | Disease Burden | Maternal Health | Child Health | Chronic Diseases | Injuries | Women'S Health | Life Course | Public Health | Epidemiology
