Professor | 魏杰 | 数字化转型顾问

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Name	魏杰
Contact Information	jiewei@xmu.edu.cn
Language ability	中文, 英文
Province	福建

Upload Avatar (500 x 500)

Name

魏杰

Contact Information

jiewei@xmu.edu.cn

Language ability

中文, 英文

Province

福建

University/Lab Affiliation and Title	厦门大学
Faculty	Medical
Academic Background & Achievements	2000-2005: 兰州大学公共卫生学院医学学士 2005-2008: 兰州大学公共卫生学院医学硕士 2008-2011: 华中科技大学公共卫生学院医学博士
Work Experience	2011.09-2014.03: 厦门大学生命科学学院博士后 2014.04-至今: 厦门大学医学院副教授

University/Lab Affiliation and Title

厦门大学

Faculty

Medical

Academic Background & Achievements

2000-2005: 兰州大学公共卫生学院医学学士
2005-2008: 兰州大学公共卫生学院医学硕士
2008-2011: 华中科技大学公共卫生学院医学博士

Work Experience

2011.09-2014.03: 厦门大学生命科学学院博士后
2014.04-至今: 厦门大学医学院副教授

Areas of Focus	环境因素引起的慢性代谢性疾病的表观遗传机制
Publications	MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1, 魏杰, 丁丁, 王涛, 刘强, 林毅, 2017 Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease, 林毅, 丁丁, 黄琦, 刘强, 陆浩, 陆毅, 池勇, 孙晓, 叶刚, 朱辉, 魏杰, 董思, 2017 miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis, 王涛, 侯杰, 李志, 郑志, 魏杰, 宋丹, 胡涛, 吴强, 杨建勇, 蔡建成, 2017 MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer, 姜晨, 陈晓, 阿拉塔尔, 魏杰, 刘辉, 2015 Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet, 魏杰, 孙晓, 陈艳, 李勇, 宋丽, 周志, 徐斌, 林毅, 徐松, 2014 The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma, 高世博, 徐斌, 丁丽华, 郑庆龙, 张磊, 郑庆峰, 李世华, 冯志杰, 魏杰, 尹志勇, 华晓, 金国华, 2014 Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice, 罗勇, 刘勇, 刘敏, 魏杰, 张勇, 侯杰, 黄伟, 王涛, 李晓, 何勇, 丁峰, 袁磊, 蔡建成, 郑峰, 杨建勇, 2014 Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice, 魏杰, 张勇, 罗勇, 王志, 毕松, 宋丹, 戴勇, 王涛, 邱磊, 文磊, 袁磊, 杨建勇, 2014 Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells, 林毅, 孙晓, 邱磊, 魏杰, 黄琦, 方成, 叶涛, 康明, 沈华, 董思, 2013 Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate, 吕志, 李刚, 李勇, 应成, 陈杰, 陈涛, 魏杰, 林毅, 姜勇, 王勇, 舒波, 徐斌, 徐松, 2013 Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets, 宋丽, 夏伟, 周志, 李勇, 林毅, 魏杰, 魏志, 徐斌, 沈杰, 李伟, 徐松, 2012 Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring, 魏志, 宋丽, 魏杰, 陈涛, 陈杰, 林毅, 夏伟, 徐斌, 李晓, 陈晓, 李勇, 徐松, 2012 Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat, 林毅, 魏杰, 李勇, 陈杰, 周志, 宋丽, 魏志, 吕志, 陈晓, 夏伟, 徐松, 2011 Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet, 魏杰, 林毅, 李勇, 应成, 陈杰, 宋丽, 周志, 吕志, 夏伟, 陈晓, 徐松, 2011 Inflammation-like glial response in rat brain induced by prenatal PFOS exposure, 曾红成, 张磊, 李勇, 王勇, 夏伟, 林毅, 魏杰, 徐松, 2011 MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate, 张磊, 李勇, 曾红成, 魏杰, 万勇, 陈杰, 徐松, 2011 Prenatal exposure to perfluorooctanesulfonate in rat resulted in long-lasting changes of expression of synapsins and synaptophysin, 曾红成, 李勇, 张磊, 王勇, 陈杰, 夏伟, 林毅, 魏杰, 吕志强, 李明, 徐松, 2011 Alterations in tumor biomarker GSTP gene methylation patterns induced by prenatal exposure to PFOS, 万勇, 李勇, 夏伟, 陈杰, 吕志强, 曾红成, 张磊, 杨伟杰, 陈涛, 林毅, 魏杰, 徐松, 2010 Electrochemical biosensor for estrogenic substance using lipid bilayers modified by Au nanoparticles, 夏伟, 李勇, 万勇, 陈涛, 魏杰, 林毅, 徐松, 2010

Areas of Focus

环境因素引起的慢性代谢性疾病的表观遗传机制

Publications

MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1, 魏杰, 丁丁, 王涛, 刘强, 林毅, 2017
Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease, 林毅, 丁丁, 黄琦, 刘强, 陆浩, 陆毅, 池勇, 孙晓, 叶刚, 朱辉, 魏杰, 董思, 2017
miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis, 王涛, 侯杰, 李志, 郑志, 魏杰, 宋丹, 胡涛, 吴强, 杨建勇, 蔡建成, 2017
MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer, 姜晨, 陈晓, 阿拉塔尔, 魏杰, 刘辉, 2015
Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet, 魏杰, 孙晓, 陈艳, 李勇, 宋丽, 周志, 徐斌, 林毅, 徐松, 2014
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma, 高世博, 徐斌, 丁丽华, 郑庆龙, 张磊, 郑庆峰, 李世华, 冯志杰, 魏杰, 尹志勇, 华晓, 金国华, 2014
Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice, 罗勇, 刘勇, 刘敏, 魏杰, 张勇, 侯杰, 黄伟, 王涛, 李晓, 何勇, 丁峰, 袁磊, 蔡建成, 郑峰, 杨建勇, 2014
Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice, 魏杰, 张勇, 罗勇, 王志, 毕松, 宋丹, 戴勇, 王涛, 邱磊, 文磊, 袁磊, 杨建勇, 2014
Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells, 林毅, 孙晓, 邱磊, 魏杰, 黄琦, 方成, 叶涛, 康明, 沈华, 董思, 2013
Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate, 吕志, 李刚, 李勇, 应成, 陈杰, 陈涛, 魏杰, 林毅, 姜勇, 王勇, 舒波, 徐斌, 徐松, 2013
Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets, 宋丽, 夏伟, 周志, 李勇, 林毅, 魏杰, 魏志, 徐斌, 沈杰, 李伟, 徐松, 2012
Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring, 魏志, 宋丽, 魏杰, 陈涛, 陈杰, 林毅, 夏伟, 徐斌, 李晓, 陈晓, 李勇, 徐松, 2012
Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat, 林毅, 魏杰, 李勇, 陈杰, 周志, 宋丽, 魏志, 吕志, 陈晓, 夏伟, 徐松, 2011
Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet, 魏杰, 林毅, 李勇, 应成, 陈杰, 宋丽, 周志, 吕志, 夏伟, 陈晓, 徐松, 2011
Inflammation-like glial response in rat brain induced by prenatal PFOS exposure, 曾红成, 张磊, 李勇, 王勇, 夏伟, 林毅, 魏杰, 徐松, 2011
MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate, 张磊, 李勇, 曾红成, 魏杰, 万勇, 陈杰, 徐松, 2011
Prenatal exposure to perfluorooctanesulfonate in rat resulted in long-lasting changes of expression of synapsins and synaptophysin, 曾红成, 李勇, 张磊, 王勇, 陈杰, 夏伟, 林毅, 魏杰, 吕志强, 李明, 徐松, 2011
Alterations in tumor biomarker GSTP gene methylation patterns induced by prenatal exposure to PFOS, 万勇, 李勇, 夏伟, 陈杰, 吕志强, 曾红成, 张磊, 杨伟杰, 陈涛, 林毅, 魏杰, 徐松, 2010
Electrochemical biosensor for estrogenic substance using lipid bilayers modified by Au nanoparticles, 夏伟, 李勇, 万勇, 陈涛, 魏杰, 林毅, 徐松, 2010

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