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魏杰
Medical School
厦门大学
福建
Language: 中文, 英文
表观遗传学
慢性疾病
代谢紊乱
环境因素
肥胖
胰岛素抵抗
2型糖尿病
基因调控
分子机制
公共卫生
Areas of Focus
- 环境因素引起的慢性代谢性疾病的表观遗传机制
Work Experience
- 2011.09-2014.03: 厦门大学生命科学学院博士后
- 2014.04-至今: 厦门大学医学院副教授
Academic Background & Achievements
- 2000-2005: 兰州大学公共卫生学院医学学士
- 2005-2008: 兰州大学公共卫生学院医学硕士
- 2008-2011: 华中科技大学公共卫生学院医学博士
Publications
- MiR-338 controls BPA-triggered pancreatic islet insulin secretory dysfunction from compensation to decompensation by targeting Pdx-1, 魏杰, 丁丁, 王涛, 刘强, 林毅, 2017
- Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease, 林毅, 丁丁, 黄琦, 刘强, 陆浩, 陆毅, 池勇, 孙晓, 叶刚, 朱辉, 魏杰, 董思, 2017
- miR-15a-3p and miR-16-1-3p Negatively Regulate Twist1 to Repress Gastric Cancer Cell Invasion and Metastasis, 王涛, 侯杰, 李志, 郑志, 魏杰, 宋丹, 胡涛, 吴强, 杨建勇, 蔡建成, 2017
- MicroRNAs in tumorigenesis, metastasis, diagnosis and prognosis of gastric cancer, 姜晨, 陈晓, 阿拉塔尔, 魏杰, 刘辉, 2015
- Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet, 魏杰, 孙晓, 陈艳, 李勇, 宋丽, 周志, 徐斌, 林毅, 徐松, 2014
- The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma, 高世博, 徐斌, 丁丽华, 郑庆龙, 张磊, 郑庆峰, 李世华, 冯志杰, 魏杰, 尹志勇, 华晓, 金国华, 2014
- Sfmbt2 10th intron-hosted miR-466(a/e)-3p are important epigenetic regulators of Nfat5 signaling, osmoregulation and urine concentration in mice, 罗勇, 刘勇, 刘敏, 魏杰, 张勇, 侯杰, 黄伟, 王涛, 李晓, 何勇, 丁峰, 袁磊, 蔡建成, 郑峰, 杨建勇, 2014
- Aldose reductase regulates miR-200a-3p/141-3p to coordinate Keap1-Nrf2, Tgfβ1/2, and Zeb1/2 signaling in renal mesangial cells and the renal cortex of diabetic mice, 魏杰, 张勇, 罗勇, 王志, 毕松, 宋丹, 戴勇, 王涛, 邱磊, 文磊, 袁磊, 杨建勇, 2014
- Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells, 林毅, 孙晓, 邱磊, 魏杰, 黄琦, 方成, 叶涛, 康明, 沈华, 董思, 2013
- Glucose and lipid homeostasis in adult rat is impaired by early-life exposure to perfluorooctane sulfonate, 吕志, 李刚, 李勇, 应成, 陈杰, 陈涛, 魏杰, 林毅, 姜勇, 王勇, 舒波, 徐斌, 徐松, 2013
- Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets, 宋丽, 夏伟, 周志, 李勇, 林毅, 魏杰, 魏志, 徐斌, 沈杰, 李伟, 徐松, 2012
- Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring, 魏志, 宋丽, 魏杰, 陈涛, 陈杰, 林毅, 夏伟, 徐斌, 李晓, 陈晓, 李勇, 徐松, 2012
- Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat, 林毅, 魏杰, 李勇, 陈杰, 周志, 宋丽, 魏志, 吕志, 陈晓, 夏伟, 徐松, 2011
- Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet, 魏杰, 林毅, 李勇, 应成, 陈杰, 宋丽, 周志, 吕志, 夏伟, 陈晓, 徐松, 2011
- Inflammation-like glial response in rat brain induced by prenatal PFOS exposure, 曾红成, 张磊, 李勇, 王勇, 夏伟, 林毅, 魏杰, 徐松, 2011
- MicroRNA expression changes during zebrafish development induced by perfluorooctane sulfonate, 张磊, 李勇, 曾红成, 魏杰, 万勇, 陈杰, 徐松, 2011
- Prenatal exposure to perfluorooctanesulfonate in rat resulted in long-lasting changes of expression of synapsins and synaptophysin, 曾红成, 李勇, 张磊, 王勇, 陈杰, 夏伟, 林毅, 魏杰, 吕志强, 李明, 徐松, 2011
- Alterations in tumor biomarker GSTP gene methylation patterns induced by prenatal exposure to PFOS, 万勇, 李勇, 夏伟, 陈杰, 吕志强, 曾红成, 张磊, 杨伟杰, 陈涛, 林毅, 魏杰, 徐松, 2010
- Electrochemical biosensor for estrogenic substance using lipid bilayers modified by Au nanoparticles, 夏伟, 李勇, 万勇, 陈涛, 魏杰, 林毅, 徐松, 2010
