Professor | Yan Yan Zhan | Asia Growth Partners

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Name	Yan Yan Zhan
Contact Information	yyzhan@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

Upload Avatar (500 x 500)

Name

Yan Yan Zhan

Contact Information

yyzhan@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2000-2004 Bachelor of Science in Biological Sciences: Xiamen University 2004-2010 Doctor of Science in Cell Biology: Xiamen University
Work Experience	2011-2013 Postdoctoral Researcher: First Affiliated Hospital of Xiamen University 2013-Present Associate Professor: School of Medicine, Xiamen University

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2000-2004 Bachelor of Science in Biological Sciences: Xiamen University
2004-2010 Doctor of Science in Cell Biology: Xiamen University

Work Experience

2011-2013 Postdoctoral Researcher: First Affiliated Hospital of Xiamen University
2013-Present Associate Professor: School of Medicine, Xiamen University

Areas of Focus	Mechanisms of tumorigenesis and development Targeted drug screening
Publications	Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells., Ruan H, Zhan YY, Hou J, Xu B, Chen B, Tian Y, Wu D, Zhao Y, Zhang Y, Chen X, Mi P, Zhang L, Zhang S, Wang X, Cao H, Zhang W, Wang H, Li H, Su Y, Zhang XK, Hu T, 2017 Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth., Li D, Zhang Y, Liu K, Zhao Y, Xu B, Xu L, Tan L, Tian Y, Li C, Zhang W, Cao H, Zhan YY, Hu T, 2017 Exo70 is an independent prognostic factor in colon cancer., Xiao L, Zheng K, Lv X, Hou J, Xu L, Zhao Y, Song F, Fan Y, Cao H, Zhang W, Hong X, Zhan YY, Hu T, 2017 Matrine induces RIP3-dependent necroptosis in cholangiocarcinoma cells., Xu B, Xu M, Tian Y, Yu Q, Zhao Y, Chen X, Mi P, Cao H, Zhang B, Song G, Zhan YY, Hu T, 2017 Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells., Zhao Y, Hou J, Mi P, Mao L, Xu L, Zhang Y, Xiao L, Cao H, Zhang W, Zhang B, Song G, Hu T, Zhan YY, 2016 Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor., Zhou H, Xu M, Gao Y, Deng Z, Cao H, Zhang W, Wang Q, Zhang B, Song G, Zhan Y, Hu T, 2014 Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells., Zhan YY, He JP, Chen HZ, Wang WJ, Cai JC, 2013 The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK., Zhan YY, Chen Y, Zhang Q, Zhuang JJ, Tian M, Chen HZ, Zhang LR, Zhang HK, He JP, Wang WJ, Wu R, Wang Y, Shi C, Yang K, Li AZ, Xin YZ, Li TY, Yang JY, Zheng ZH, Yu CD, Lin SC, Chang C, Huang PQ, Lin T, Wu Q, 2012 Cytosporone B is an agonist for nuclear orphan receptor Nur77., Zhan Y, Du X, Chen H, Liu J, Zhao B, Huang D, Li G, Xu Q, Zhang M, Weimer BC, Chen D, Cheng Z, Zhang L, Li Q, Li S, Zheng Z, Song S, Huang Y, Ye Z, Su W, Lin SC, Shen Y, Wu Q, 2008

Areas of Focus

Mechanisms of tumorigenesis and development
Targeted drug screening

Publications

Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells., Ruan H, Zhan YY, Hou J, Xu B, Chen B, Tian Y, Wu D, Zhao Y, Zhang Y, Chen X, Mi P, Zhang L, Zhang S, Wang X, Cao H, Zhang W, Wang H, Li H, Su Y, Zhang XK, Hu T, 2017
Berberine inhibits colitis-associated tumorigenesis via suppressing inflammatory responses and the consequent EGFR signaling-involved tumor cell growth., Li D, Zhang Y, Liu K, Zhao Y, Xu B, Xu L, Tan L, Tian Y, Li C, Zhang W, Cao H, Zhan YY, Hu T, 2017
Exo70 is an independent prognostic factor in colon cancer., Xiao L, Zheng K, Lv X, Hou J, Xu L, Zhao Y, Song F, Fan Y, Cao H, Zhang W, Hong X, Zhan YY, Hu T, 2017
Matrine induces RIP3-dependent necroptosis in cholangiocarcinoma cells., Xu B, Xu M, Tian Y, Yu Q, Zhao Y, Chen X, Mi P, Cao H, Zhang B, Song G, Zhan YY, Hu T, 2017
Exo70 is transcriptionally up-regulated by hepatic nuclear factor 4α and contributes to cell cycle control in hepatoma cells., Zhao Y, Hou J, Mi P, Mao L, Xu L, Zhang Y, Xiao L, Cao H, Zhang W, Zhang B, Song G, Hu T, Zhan YY, 2016
Matrine induces caspase-independent program cell death in hepatocellular carcinoma through bid-mediated nuclear translocation of apoptosis inducing factor., Zhou H, Xu M, Gao Y, Deng Z, Cao H, Zhang W, Wang Q, Zhang B, Song G, Zhan Y, Hu T, 2014
Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells., Zhan YY, He JP, Chen HZ, Wang WJ, Cai JC, 2013
The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK., Zhan YY, Chen Y, Zhang Q, Zhuang JJ, Tian M, Chen HZ, Zhang LR, Zhang HK, He JP, Wang WJ, Wu R, Wang Y, Shi C, Yang K, Li AZ, Xin YZ, Li TY, Yang JY, Zheng ZH, Yu CD, Lin SC, Chang C, Huang PQ, Lin T, Wu Q, 2012
Cytosporone B is an agonist for nuclear orphan receptor Nur77., Zhan Y, Du X, Chen H, Liu J, Zhao B, Huang D, Li G, Xu Q, Zhang M, Weimer BC, Chen D, Cheng Z, Zhang L, Li Q, Li S, Zheng Z, Song S, Huang Y, Ye Z, Su W, Lin SC, Shen Y, Wu Q, 2008

Tumorigenesis Development Mechanisms Targeted Drug Screening Exo70 Exocyst Vesicle Fusion

Xiangming Fang - Zhejiang University

Yu Feng - Zhejiang University

Hao Wang - Zhejiang University

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