Professor | Li Zhong | Asia Growth Partners

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Name	Li Zhong
Contact Information	zhongli@xmu.edu.cn
Language ability	Chinese, English
Province	Fujian

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Name

Li Zhong

Contact Information

zhongli@xmu.edu.cn

Language ability

Chinese, English

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	2006~2010 Bachelor of Science in Biotechnology: East China University of Technology 2010~2015 Doctor of Science in Physiology: Xiamen University
Work Experience	2016~2019 - Xiamen University School of Medicine - Postdoctoral Researcher 2019~2021 - Xiamen University School of Medicine - Assistant Professor 2021~Present - Xiamen University School of Medicine - Associate Professor
Awards	First Class Grant from the 60th Batch of China Postdoctoral Science Foundation Special Grant from the 10th Batch of China Postdoctoral Science Foundation Youth Project of the National Natural Science Foundation of China

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

2006~2010 Bachelor of Science in Biotechnology: East China University of Technology
2010~2015 Doctor of Science in Physiology: Xiamen University

Work Experience

2016~2019 - Xiamen University School of Medicine - Postdoctoral Researcher
2019~2021 - Xiamen University School of Medicine - Assistant Professor
2021~Present - Xiamen University School of Medicine - Associate Professor

Awards

First Class Grant from the 60th Batch of China Postdoctoral Science Foundation
Special Grant from the 10th Batch of China Postdoctoral Science Foundation
Youth Project of the National Natural Science Foundation of China

Areas of Focus	Physiological and pathological functions of microglia in Alzheimer's Disease TREM2 gene mutation and Alzheimer's Disease risk Role and mechanism of immune-related complement proteins in Alzheimer's Disease
Publications	Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model, Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu C C, Du D, Sun H, Wen L, Xu H, Bu G, Chen X F, 2019 Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2), Zhong L, Wang Z, Wang D, Wang Z, Martens Y A, Wu L, Xu Y, Wang K, Li J, Huang R, Can D, Xu H, Bu G, Chen X F, 2018 TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway, Zhong L, Zhang Z L, Li X, Liao C, Mou P, Wang T, Wang Z, Wang Z, Wei M, Xu H, Bu G, Chen X F, 2017 Soluble TREM2 induces inflammatory responses and enhances microglial survival, Zhong L, Chen X F, Wang T, Wang Z, Liao C, Wang Z, Huang R, Wang D, Li X, Wu L, Jia L, Zheng H, Painter M, Atagi Y, Liu C C, Zhang Y W, Fryer J D, Xu H, Bu G, 2017 A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism, Zhong L, Xie YZ, Cao TT, Wang Z, Wang T, Li X, Shen RC, Xu H, Bu G, Chen XF, 2016 DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response, Zhong L, Chen X F, Zhang Z L, Wang Z, Shi X Z, Xu K, Zhang Y W, Xu H, Bu G, 2015

Areas of Focus

Physiological and pathological functions of microglia in Alzheimer's Disease
TREM2 gene mutation and Alzheimer's Disease risk
Role and mechanism of immune-related complement proteins in Alzheimer's Disease

Publications

Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model, Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu C C, Du D, Sun H, Wen L, Xu H, Bu G, Chen X F, 2019
Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2), Zhong L, Wang Z, Wang D, Wang Z, Martens Y A, Wu L, Xu Y, Wang K, Li J, Huang R, Can D, Xu H, Bu G, Chen X F, 2018
TREM2/DAP12 Complex Regulates Inflammatory Responses in Microglia via the JNK Signaling Pathway, Zhong L, Zhang Z L, Li X, Liao C, Mou P, Wang T, Wang Z, Wang Z, Wei M, Xu H, Bu G, Chen X F, 2017
Soluble TREM2 induces inflammatory responses and enhances microglial survival, Zhong L, Chen X F, Wang T, Wang Z, Liao C, Wang Z, Huang R, Wang D, Li X, Wu L, Jia L, Zheng H, Painter M, Atagi Y, Liu C C, Zhang Y W, Fryer J D, Xu H, Bu G, 2017
A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism, Zhong L, Xie YZ, Cao TT, Wang Z, Wang T, Li X, Shen RC, Xu H, Bu G, Chen XF, 2016
DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response, Zhong L, Chen X F, Zhang Z L, Wang Z, Shi X Z, Xu K, Zhang Y W, Xu H, Bu G, 2015

Microglia Alzheimer'S Disease Trem2 Gene Mutation Complement Proteins Pathology Physiology Immune Response Neurodegeneration Risk Factors

Fang Marong - Zhejiang University

Xiaofen Chen - Xiamen University

Gao Yue - Xiamen University

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