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Bin Xu
Medical School
Xiamen University
Fujian
Language: Chinese, English
Epigenetics
Hepatocellular Carcinoma
Histone Methylation
Chronic Inflammation
Menin
Mll Protein
Gene Expression
Liver Cancer
H3K4
Therapeutic Targets
Areas of Focus
- Epigenetics of Hepatocellular Carcinoma
Work Experience
- 2007-2009 - Xiamen University School of Medicine - Assistant Experimenter
- 2009-2011 - Xiamen University School of Medicine - Experimenter
- 2015-2016 - University of Texas Southwestern Medical Center - Postdoctoral Researcher
- 2014-present - Xiamen University School of Medicine - Assistant Professor
Academic Background & Achievements
- 2000-2004 Bachelor of Science in Biotechnology: Yantai University
- 2004-2007 Master of Science in Biochemistry and Molecular Biology: Xiamen University
- 2011-2014 Doctor of Science in Physiology: Xiamen University
- Published 9 SCI papers, including 3 as first author in prestigious journals
Publications
- Epigenetic alterations contribute to promoter activity of imprinting gene IGF2, Qi-Fan Zheng, Bin Xu, Hui-Min Wang, Li-Hong Ding, Jin-Yang Liu, Ling-Yu Zhu, Huan Qiu, Li Zhang, Guang-Yi Ni, Jing Ye, Shu-Bin Gao, Guang-Hui Jin, 2018
- The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma, Shu-Bin Gao, Bin Xu, Li-Hong Ding, Qi-Lin Zheng, Li Zhang, Qi-Fan Zheng, Shan-Hua Li, Zi-Jie Feng, Jie Wei, Zhen-Yu Yin, Xianxin Hua, Guang-Hui Jin, 2014
- EZH2 Represses Target Genes through H3K27-Dependent and H3K27-Independent Mechanisms in Hepatocellular Carcinoma, Shu-Bin Gao, Qi-Fan Zheng, Bin Xu, Chang-Bao Pan, Kang-Li Li, Yue Zhao, Qi-Lin Zheng, Xiao Lin, Li-Xiang Xue, Guang-Hui Jin, 2014
- Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription, Xu Bin, Li Shan-Hua, Zheng Rong, Gao Shu-Bin, Ding Li-Hong, Yin Zhen-Yu, Lin Xiao, Feng Zi-Jie, Zhang Sheng, Wang Xiao-Min, Jin Guang-Hui, 2013
- Tumor Suppressor Menin Represses Paired Box Gene 2 Expression via Wilms Tumor Suppressor Protein-Polycomb Group Complex, Xu Bin, Zeng De-quan, Wu Yuan, Zheng Rong, Gu Le, Lin Xiao, Hua Xianxin, Jin Guang-Hui, 2011
- Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin, Gao S-B, Feng Z-J, Xu B, Wu Y, Yin P, Yang Y, Hua X-X, Jin G-H, 2009
