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Rongquan Xiao
Medical School
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Epigenetics
Tumors
Molecular Mechanisms
Cancer Research
Gene Regulation
Biological Applications
Disease Mechanisms
Therapeutic Targets
Molecular Biology
Cellular Processes
Areas of Focus
- Epigenetic regulatory factors in tumors: function, molecular mechanisms, and applications
Work Experience
- 2023/06 - Present: Southern University of Science and Technology, Medical School, Research Assistant Professor
- 2020/07 - 2023/06: Xiamen University, School of Pharmacy, Postdoctoral Researcher
Academic Background & Achievements
- 2014/09 - 2020/06 PhD in Chemical Biology: Xiamen University
- 2020 PhD, supervised by Professor Liu Wen
Publications
- A specific JMJD6 inhibitor potently suppresses multiple types of cancers both in vitro and in vivo, Xiao RQ, Ran T, Huang QX, Hu GS, Fan DM, Yi J, Liu W, 2022
- JMJD6 licenses estrogen receptor a-dependent enhancer and coding gene activation by modulating the recruitment of the CARM1/MED12 co-activator complex, Gao WW, Xiao RQ, Zhang WG, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W, 2018
- In Silico Discovery of JMJD6 Inhibitors for Cancer Treatment, Ran T, Xiao RQ, Huang QX, Yuan HL, Lu T, Liu W, 2019
- Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation, Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W, 2015
- ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer, Yi J, Wang L, Du J, Wang MY, Shen HF, Liu ZY, Qin Y, Liu J, Hu GS, Xiao RQ, Ding JC, Chen HJ, Wang HJ, Huang HH, Ouyang GL, Liu W, 2023
- A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor a-dependent transcriptional activation and breast carcinogenesis, Peng BL, Li WJ, Ding JC, He YH, Ran T, Xie BL, Wang ZR, Shen HF, Xiao RQ, Gao WW, Ye TY, Gao X, Liu W, 2020
- Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation, Zhang WJ, Wu XN, Shi TT, Xu HT, Yi J, Shen HF, Huang MF, Su XY, Wang FF, Peng BL, Xiao RQ, Gao WW, Ding JC, Liu W, 2016
- Patient-derived xenografts (PDX) identify JMJD6 inhibitor as an effective therapeutic medicine in colorectal cancer, Ye F, You J, Xia L, Lian JB, Xiao RQ, Ran T, Gao X, Li JY, Zhao X, Gao J, Lin HX, Zheng JN, Liu W, 2019
Awards
- Xiamen University Life Sciences and Human Health Group 2021 Outstanding Postdoctoral Support, 2021
- Xiamen University 'Outstanding Graduate' honor, 2020
- Xiamen University School of Pharmacy 'Zhuang Jin Scholarship' Outstanding Contribution Award, 2018
