Upload Avatar (500 x 500)
肖荣权
Medical School
南方科技大学
广东省
Language: 中文, 英语
表观遗传学
肿瘤
分子机制
癌症研究
基因调控
生物应用
疾病机制
治疗靶点
分子生物学
细胞过程
Areas of Focus
- 肿瘤中的表观遗传调控因子：功能、分子机制及其应用
Work Experience
- 2023/06 - 至今 南方科技大学, 医学院, 研究助理教授
- 2020/07 - 2023/06 厦门大学, 药学院，博士后
Academic Background & Achievements
- 2014/09 - 2020/06 厦门大学, 化学生物学, 博士
- 2020 博士, 导师为刘文教授
Publications
- A specific JMJD6 inhibitor potently suppresses multiple types of cancers both in vitro and in vivo, Xiao RQ, Ran T, Huang QX, Hu GS, Fan DM, Yi J, Liu W, 2022
- JMJD6 licenses estrogen receptor a-dependent enhancer and coding gene activation by modulating the recruitment of the CARM1/MED12 co-activator complex, Gao WW, Xiao RQ, Zhang WG, Hu YR, Peng BL, Li WJ, He YH, Shen HF, Ding JC, Huang QX, Ye TY, Li Y, Liu ZY, Ding R, Rosenfeld MG, Liu W, 2018
- In Silico Discovery of JMJD6 Inhibitors for Cancer Treatment, Ran T, Xiao RQ, Huang QX, Yuan HL, Lu T, Liu W, 2019
- Arginine methylation of HSP70 regulates retinoid acid-mediated RARβ2 gene activation, Gao WW, Xiao RQ, Peng BL, Xu HT, Shen HF, Huang MF, Shi TT, Yi J, Zhang WJ, Wu XN, Gao X, Lin XZ, Dorrestein PC, Rosenfeld MG, Liu W, 2015
- ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer, Yi J, Wang L, Du J, Wang MY, Shen HF, Liu ZY, Qin Y, Liu J, Hu GS, Xiao RQ, Ding JC, Chen HJ, Wang HJ, Huang HH, Ouyang GL, Liu W, 2023
- A hypermethylation strategy utilized by enhancer-bound CARM1 to promote estrogen receptor a-dependent transcriptional activation and breast carcinogenesis, Peng BL, Li WJ, Ding JC, He YH, Ran T, Xie BL, Wang ZR, Shen HF, Xiao RQ, Gao WW, Ye TY, Gao X, Liu W, 2020
- Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation, Zhang WJ, Wu XN, Shi TT, Xu HT, Yi J, Shen HF, Huang MF, Su XY, Wang FF, Peng BL, Xiao RQ, Gao WW, Ding JC, Liu W, 2016
- Patient-derived xenografts (PDX) identify JMJD6 inhibitor as an effective therapeutic medicine in colorectal cancer, Ye F, You J, Xia L, Lian JB, Xiao RQ, Ran T, Gao X, Li JY, Zhao X, Gao J, Lin HX, Zheng JN, Liu W, 2019
Awards
- 厦门大学生命科学与人类健康学科群2021年度优秀博士后资助，2021
- 厦门大学“优秀毕业生”荣誉称号，2020
- 厦门大学药学院“庄瑾奖学金”突出贡献奖，2018
