Professor | 贾宁 | 数字化转型顾问

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Name	贾宁
Contact Information	jian@sustech.edu.cn
Language ability	中文, 英语
Province	广东省

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Name

贾宁

Contact Information

jian@sustech.edu.cn

Language ability

中文, 英语

Province

广东省

University/Lab Affiliation and Title	南方科技大学
Faculty	Medical School
Academic Background & Achievements	2006-2010 学士：中国海洋大学 2010-2016 博士：中国科学技术大学，导师：周丛照、陈宇星教授入选《麻省理工科技评论》“35岁以下科技创新35人”亚太区榜单（2022）美国布拉瓦尼克区域青年科学家化学奖获得者（2020）
Work Experience	2022.06-至今副教授，南方科技大学医学院 2021.05-2022.05 助理教授，南方科技大学医学院 2017-2021 博士后，美国纪念斯隆凯特琳癌症中心，导师：Dinshaw J. Patel教授
Awards	2024: 入选Journal of Biological Chemistry (JBC)期刊的Editorial Board member 2022: 入选《麻省理工科技评论》“35岁以下科技创新35人”亚太区榜单 2020: 美国布拉瓦尼克区域青年科学家化学奖 2016: 蔡司-斑马鱼科学研究奖 2010: 山东省优秀毕业生 2007，2009: 国家奖学金

University/Lab Affiliation and Title

南方科技大学

Faculty

Medical School

Academic Background & Achievements

2006-2010 学士：中国海洋大学
2010-2016 博士：中国科学技术大学，导师：周丛照、陈宇星教授
入选《麻省理工科技评论》“35岁以下科技创新35人”亚太区榜单（2022）
美国布拉瓦尼克区域青年科学家化学奖获得者（2020）

Work Experience

2022.06-至今副教授，南方科技大学医学院
2021.05-2022.05 助理教授，南方科技大学医学院
2017-2021 博士后，美国纪念斯隆凯特琳癌症中心，导师：Dinshaw J. Patel教授

Awards

2024: 入选Journal of Biological Chemistry (JBC)期刊的Editorial Board member
2022: 入选《麻省理工科技评论》“35岁以下科技创新35人”亚太区榜单
2020: 美国布拉瓦尼克区域青年科学家化学奖
2016: 蔡司-斑马鱼科学研究奖
2010: 山东省优秀毕业生
2007，2009: 国家奖学金

Areas of Focus	微生物与宿主免疫系统相互作用的分子机制基于微生物与宿主免疫系统相互作用分子机制的生物技术工具开发
Publications	Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system, Zhang, J.T., Liu, X.Y., Li, Z.L., Wei, X.Y., Song, X.Y., Cui, N., Zhong, J., Li, H., and Jia, N., 2024 Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system, Zhang, J.T., Wei, X. Y., Cui, N., Tian, R., Jia, N., 2023 Type IV-A CRISPR-Csf complex: assembly, dsDNA targeting and CasDinG recruitment, Cui, N., Zhang, J.T., Li, Y., Liu, Y., Liu, X.Y., Wang, C., Huang, H., and Jia, N., 2023 Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05, Duan, Z., Zhang, X., Zhang, J.T., Li, S, Liu, R., Sun, J., Zhao, Q., Jia, N., Jia, N., and Zhu, J.K., 2023 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase, Cui, N., Zhang, J.T., Li, Z., Liu, X.Y.,Wang, C., Huang, H., and Jia, N., 2022 Bacterial origins of cyclic nucleotide-activated antiviral immune signaling, Patel, D.J., Yu, Y., and Jia, N., 2022 Structure-based evolutionary relationship between IscB and Cas9, Jia, N. & Patel, D. J., 2022 Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins, Jia, N., Patel. D. J., 2021 A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity, Meeske A. J., Jia, N., Cassel A.K., Kozlova A., Liao J., Wiedmann M., Patel D. J., Marraffini L. A., 2020 Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex, Jia, N., Xie, W., De La Cruz, J.M., Eng, E.T., Patel, D.J.*, 2020 CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4 Cleavage with ApA

Areas of Focus

微生物与宿主免疫系统相互作用的分子机制
基于微生物与宿主免疫系统相互作用分子机制的生物技术工具开发

Publications

Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system, Zhang, J.T., Liu, X.Y., Li, Z.L., Wei, X.Y., Song, X.Y., Cui, N., Zhong, J., Li, H., and Jia, N.*, 2024
Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system, Zhang, J.T., Wei, X. Y., Cui, N., Tian, R., Jia, N.*, 2023
Type IV-A CRISPR-Csf complex: assembly, dsDNA targeting and CasDinG recruitment, Cui, N., Zhang, J.T., Li, Y., Liu, Y., Liu, X.Y., Wang, C., Huang, H.*, and Jia, N.*, 2023
Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05, Duan, Z., Zhang, X., Zhang, J.T., Li, S, Liu, R., Sun, J., Zhao, Q., Jia, N., Jia, N.*, and Zhu, J.K.*, 2023
Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase, Cui, N., Zhang, J.T., Li, Z., Liu, X.Y.,Wang, C., Huang, H.*, and Jia, N.*, 2022
Bacterial origins of cyclic nucleotide-activated antiviral immune signaling, Patel, D.J.*, Yu, Y., and Jia, N., 2022
Structure-based evolutionary relationship between IscB and Cas9, Jia, N.* & Patel, D. J.*, 2022
Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins, Jia, N.*, Patel. D. J.*, 2021
A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity, Meeske A. J., Jia, N., Cassel A.K., Kozlova A., Liao J., Wiedmann M., Patel D. J.*, Marraffini L. A.*, 2020
Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex, Jia, N.*, Xie, W., De La Cruz, J.M., Eng, E.T., Patel, D.J.*, 2020
CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4 Cleavage with ApA

微生物相互作用宿主免疫系统分子机制 Crispr-Cas系统噬菌体抵抗质粒入侵生物化学分子生物学微生物学结构生物学

李婉秋 - 南方科技大学

宋军伟 - 南方科技大学

肖荣权 - 南方科技大学

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