Professor | Yuhang Chen | Asia Growth Partners

Name	Yuhang Chen
Contact Information	yuhang.chen@genetics.ac.cn
Language ability	English, Chinese
Province	Beijing

Name

Yuhang Chen

Contact Information

yuhang.chen@genetics.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Agriculture and Biotechnology
Academic Background & Achievements	1998-09--2002-07 PhD: Tsinghua University 1994-09--1998-07 Bachelor: Beijing Medical University
Work Experience	2012-11--Present, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Researcher 2006-04--2012-10, Columbia University Department of Biochemistry and Molecular Biophysics, Postdoctoral Researcher, Assistant Researcher 2002-09--2006-03, Columbia University Department of Biology, Postdoctoral Researcher
Awards	Exploration and Reform in the Teaching Process of Signal Transduction Course, Second Prize, Institute Level, 2020 Outstanding Graduate Course, Research Institute (School), 2019 Outstanding Graduate Course, Institute Level, 2019

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Agriculture and Biotechnology

Academic Background & Achievements

1998-09--2002-07 PhD: Tsinghua University
1994-09--1998-07 Bachelor: Beijing Medical University

Work Experience

2012-11--Present, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Researcher
2006-04--2012-10, Columbia University Department of Biochemistry and Molecular Biophysics, Postdoctoral Researcher, Assistant Researcher
2002-09--2006-03, Columbia University Department of Biology, Postdoctoral Researcher

Awards

Exploration and Reform in the Teaching Process of Signal Transduction Course, Second Prize, Institute Level, 2020
Outstanding Graduate Course, Research Institute (School), 2019
Outstanding Graduate Course, Institute Level, 2019

Areas of Focus	Structural Biology Molecular Design Breeding Bioengineering
Publications	Structure and activation mechanism of the rice Salt Overly Sensitive 1(SOS1) Na+/H+ antiporter, Zhang, Xiangyun; Tang, Linghui; Nie, Jiawei; Chen, Yuhang, 2023 A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis, Yusen Zhou, Tian Zhang, Xiaocui Wang, Wenqiang Wu, Jingjing Xing, Zuliang Li, Xin Qiao, Chunrui Zhang, Xiaohang Wang, Guangshun Wang, Wenhui Li, Shenglong Bai, Zhi Li, Yuanzhen Suo, Jiajia Wang, Yanli Niu, Junli Zhang, Chen Lan, Zhubing Hu, Baozhu Li, Xuebin Zhang, Wei Wang, David W. Galbraith, Yuhang Chen, Siyi Guo, Chun-Peng Song, 2023 WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance, Wang, Wei; Qin, Li; Zhang, Wenjing; Tang, Linghui; Zhang, Chao; Dong, Xiaojing; Miao, Pei; Shen, Meng; Du, Huilong; Cheng, Hangyuan; Wang, Ke; Zhang, Xiangyun; Su, Min; Lu, Hongwei; Li, Chang; Gao, Qiang; Zhang, Xiaojuan; Huang, Yun; Liang, Chengzhi; Zhou, JianMin; Chen, Yuhang, 2023 A wheat resistosome defines common principles of immune receptor channels, Foerderer, Alexander; Li, Ertong; Lawson, Aaron W; Deng, Yanan; Sun, Yue; Logemann, Elke; Zhang, Xiaoxiao; Wen, Jie; Han, Zhifu; Chang, Junbiao; Chen, Yuhang; SchulzeLefert, Paul; Chai, Jijie, 2022 Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels, Qin, Li; Tang, Linghui; Xu, Jiashu; Zhang, Xianhui; Zhu, Yun; Zhang, Chunrui; Wang, Meihua; Liu, Xuelei; Li, Fei; Sun, Fei; Su, Min; Zhai, Yujia; Chen, Yuhang, 2022 EAR APICAL DEGENERATION1 regulates maize ear development by maintaining malate supply for apical inflorescence, Pei, Yuanrong; Deng, Yanan; Zhang, Huairen; Zhang, Zhaogui; Liu, Jie; Chen, Zhibin; Cai, Darun; Li, Kai; Du, Yimo; Zang, Jie; Xin, Peiyong; Chu, Jinfang; Chen, Yuhang; Zhao, Li; Liu, Juan; Chen, Huabang, 2022 The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling, Bi, Guozhi; Su, Min; Li, Nan; Liang, Yu; Dang, Song; Xu, Jiachao; Hu, Meijuan; Wang, Jizong; Zou, Minxia; Deng, Yanan; Li, Qiyu; Huang, Shijia; Li, Jiejie; Chai, Jijie; He, Kangmin; Chen, Yuhang; Zhou, JianMin, 2021 Structure and activity of SLAC1 channels for stomatal signaling in leaves, Deng, Yanan; Kashtoh, Hamdy; Wang, Quan; Zhen, Guangxiao; Li, Qiyu; Tang, Linghui; Gao, Hailong; Zhang, Chunrui; Qin, Li; Su, Min; Li, Fei; Huang, Xiahe; Wang, Yingchun; Xie, Qi; Clarke, Oliver B; Hendrickson, Wayne A; Chen, Yuhang, 2021 Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity, Jin, Shuai; Fei, Hongyuan; Zhu, Zixu; Luo, Yingfeng; Liu, Jinxing; Gao, Shenghan; Zhang, Feng; Chen, YuHang; Wang, Yanpeng; Gao, Caixia, 2020 Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors, Li, Chao; Zhang, Rui; Meng, Xiangbing; Chen, Sha; Zong, Yuan; Lu, Chunju; Qiu, JinLong; Chen, YuHang; Li, Jiayang; Gao, Caixia, 2020 Structural basis for activity of TRIC counter-ion channels in calcium release, Wang, Xiaohui; Su, Min; Gao, Feng; Xie, Wenjun; Zeng, Yang; Li, Delin; Liu, Xuelei; Zhao, Hong; Qin, Li; Li, Fei; Liu, Qun; Clarke, Oliver B; Lam, Sin Man; Shui, GuangHou; Hendrickson, Wayne A; Chen, Yuhang, 2019 Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation, Yang, Jinpu; Sun, Siyu; Zhang, Shu; Gonzalez, Marlyn; Dong, Qianhua; Chi, Zhongxuan; Chen, Yuhang; Li, Fei, 2018 Structural basis for conductance through TRIC cation channels, Min Su, Feng Gao, Qi Yuan, Yang Mao, Delin Li, Youzhong Guo, Cheng Yang, Xiaohui Wang, Renato Bruni, Brian Kloss, Hong Zhao, Yang Zeng, Faben Zhang, Andrew R Marks, Wayne A Hendrickson, Yuhang Chen, 2017 Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex, He, Haijin; Li, Yang; Dong, Qianhua; Chang, AnYun; Gao, Feng; Chi, Zhongxuan; Su, Min; Zhang, Faben; Ban, Hyoju; Martienssen, Rob; Chen, Yuhang; Li, Fei, 2017 Resistance to Mutant Group 2 Influenza Virus Neuraminidases of an Oseltamivir-Zanamivir Hybrid Inhibitor, Wu, Yan; Gao, Feng; Qi, Jianxun; Bi, Yuhai; Fu, Lifeng; Mohan, Sankar; Chen, Yuhang; Li, Xuebing; Pinto, B Mario; Vavricka, Christopher J; Tien, Po; Gao, George F, 2016 Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading, Dong, Qianhua; Yin, FengXiang; Gao, Feng; Shen, Yuan; Zhang, Faben; Li, Yang; He, Haijin; Gonzalez, Marlyn; Yang, Jinpu; Zhang, Shu; Su, Min; Chen, YuHang; Li, Fei, 2016 Homology structure of the SLAC1 anion channel for stomata closure in leaves, Chen, Yuhang, 2010 Functional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca2+ channel beta-subunits, Chen, Yuhang; He, Linling; Buchanan, Douglas R; Zhang, Yun; Fitzmaurice, Aileen; Yang, Jian, 2009 Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion, Giraudo, Claudio G; GarciaDiaz, Alejandro; Eng, William S; Chen, Yuhang; Hendrickson, Wayne A; Melia, Thomas J; Rothman, James E, 2009 Origin of the Voltage Dependence of G-Protein Regulation of P/Q-type Ca2+ Channels, Zhang, Yun; Chen, YuHang; Bangaru, Saroja D; He, Linling; Abele, Kathryn; Tanabe, Shihori; Kozasa, Tohru; Yang, Jian, 2008 Functional modularity of the beta-subunit of voltage-gated Ca2+ channels, He, Linling; Zhang, Yun; Chen, Yuhang; Yamada, Yoichi; Yang, Jian, 2007 Structural basis of the alpha(1)-beta subunit interaction of voltage-gated Ca2+ channels, Chen, YH; Li, MH; Zhang, Y; He, LL; Yamada, Y; Fitzmaurice, A; Shen, Y; Zhang, HL; Tong, L; Yang, J, 2004

Areas of Focus

Structural Biology
Molecular Design Breeding
Bioengineering

Publications

Structure and activation mechanism of the rice Salt Overly Sensitive 1(SOS1) Na+/H+ antiporter, Zhang, Xiangyun; Tang, Linghui; Nie, Jiawei; Chen, Yuhang, 2023
A maize epimerase modulates cell wall synthesis and glycosylation during stomatal morphogenesis, Yusen Zhou, Tian Zhang, Xiaocui Wang, Wenqiang Wu, Jingjing Xing, Zuliang Li, Xin Qiao, Chunrui Zhang, Xiaohang Wang, Guangshun Wang, Wenhui Li, Shenglong Bai, Zhi Li, Yuanzhen Suo, Jiajia Wang, Yanli Niu, Junli Zhang, Chen Lan, Zhubing Hu, Baozhu Li, Xuebin Zhang, Wei Wang, David W. Galbraith, Yuhang Chen, Siyi Guo, Chun-Peng Song, 2023
WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance, Wang, Wei; Qin, Li; Zhang, Wenjing; Tang, Linghui; Zhang, Chao; Dong, Xiaojing; Miao, Pei; Shen, Meng; Du, Huilong; Cheng, Hangyuan; Wang, Ke; Zhang, Xiangyun; Su, Min; Lu, Hongwei; Li, Chang; Gao, Qiang; Zhang, Xiaojuan; Huang, Yun; Liang, Chengzhi; Zhou, JianMin; Chen, Yuhang, 2023
A wheat resistosome defines common principles of immune receptor channels, Foerderer, Alexander; Li, Ertong; Lawson, Aaron W; Deng, Yanan; Sun, Yue; Logemann, Elke; Zhang, Xiaoxiao; Wen, Jie; Han, Zhifu; Chang, Junbiao; Chen, Yuhang; SchulzeLefert, Paul; Chai, Jijie, 2022
Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels, Qin, Li; Tang, Linghui; Xu, Jiashu; Zhang, Xianhui; Zhu, Yun; Zhang, Chunrui; Wang, Meihua; Liu, Xuelei; Li, Fei; Sun, Fei; Su, Min; Zhai, Yujia; Chen, Yuhang, 2022
EAR APICAL DEGENERATION1 regulates maize ear development by maintaining malate supply for apical inflorescence, Pei, Yuanrong; Deng, Yanan; Zhang, Huairen; Zhang, Zhaogui; Liu, Jie; Chen, Zhibin; Cai, Darun; Li, Kai; Du, Yimo; Zang, Jie; Xin, Peiyong; Chu, Jinfang; Chen, Yuhang; Zhao, Li; Liu, Juan; Chen, Huabang, 2022
The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling, Bi, Guozhi; Su, Min; Li, Nan; Liang, Yu; Dang, Song; Xu, Jiachao; Hu, Meijuan; Wang, Jizong; Zou, Minxia; Deng, Yanan; Li, Qiyu; Huang, Shijia; Li, Jiejie; Chai, Jijie; He, Kangmin; Chen, Yuhang; Zhou, JianMin, 2021
Structure and activity of SLAC1 channels for stomatal signaling in leaves, Deng, Yanan; Kashtoh, Hamdy; Wang, Quan; Zhen, Guangxiao; Li, Qiyu; Tang, Linghui; Gao, Hailong; Zhang, Chunrui; Qin, Li; Su, Min; Li, Fei; Huang, Xiahe; Wang, Yingchun; Xie, Qi; Clarke, Oliver B; Hendrickson, Wayne A; Chen, Yuhang, 2021
Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity, Jin, Shuai; Fei, Hongyuan; Zhu, Zixu; Luo, Yingfeng; Liu, Jinxing; Gao, Shenghan; Zhang, Feng; Chen, YuHang; Wang, Yanpeng; Gao, Caixia, 2020
Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors, Li, Chao; Zhang, Rui; Meng, Xiangbing; Chen, Sha; Zong, Yuan; Lu, Chunju; Qiu, JinLong; Chen, YuHang; Li, Jiayang; Gao, Caixia, 2020
Structural basis for activity of TRIC counter-ion channels in calcium release, Wang, Xiaohui; Su, Min; Gao, Feng; Xie, Wenjun; Zeng, Yang; Li, Delin; Liu, Xuelei; Zhao, Hong; Qin, Li; Li, Fei; Liu, Qun; Clarke, Oliver B; Lam, Sin Man; Shui, GuangHou; Hendrickson, Wayne A; Chen, Yuhang, 2019
Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation, Yang, Jinpu; Sun, Siyu; Zhang, Shu; Gonzalez, Marlyn; Dong, Qianhua; Chi, Zhongxuan; Chen, Yuhang; Li, Fei, 2018
Structural basis for conductance through TRIC cation channels, Min Su, Feng Gao, Qi Yuan, Yang Mao, Delin Li, Youzhong Guo, Cheng Yang, Xiaohui Wang, Renato Bruni, Brian Kloss, Hong Zhao, Yang Zeng, Faben Zhang, Andrew R Marks, Wayne A Hendrickson, Yuhang Chen, 2017
Coordinated regulation of heterochromatin inheritance by Dpb3-Dpb4 complex, He, Haijin; Li, Yang; Dong, Qianhua; Chang, AnYun; Gao, Feng; Chi, Zhongxuan; Su, Min; Zhang, Faben; Ban, Hyoju; Martienssen, Rob; Chen, Yuhang; Li, Fei, 2017
Resistance to Mutant Group 2 Influenza Virus Neuraminidases of an Oseltamivir-Zanamivir Hybrid Inhibitor, Wu, Yan; Gao, Feng; Qi, Jianxun; Bi, Yuhai; Fu, Lifeng; Mohan, Sankar; Chen, Yuhang; Li, Xuebing; Pinto, B Mario; Vavricka, Christopher J; Tien, Po; Gao, George F, 2016
Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading, Dong, Qianhua; Yin, FengXiang; Gao, Feng; Shen, Yuan; Zhang, Faben; Li, Yang; He, Haijin; Gonzalez, Marlyn; Yang, Jinpu; Zhang, Shu; Su, Min; Chen, YuHang; Li, Fei, 2016
Homology structure of the SLAC1 anion channel for stomata closure in leaves, Chen, Yuhang, 2010
Functional dissection of the intramolecular Src homology 3-guanylate kinase domain coupling in voltage-gated Ca2+ channel beta-subunits, Chen, Yuhang; He, Linling; Buchanan, Douglas R; Zhang, Yun; Fitzmaurice, Aileen; Yang, Jian, 2009
Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion, Giraudo, Claudio G; GarciaDiaz, Alejandro; Eng, William S; Chen, Yuhang; Hendrickson, Wayne A; Melia, Thomas J; Rothman, James E, 2009
Origin of the Voltage Dependence of G-Protein Regulation of P/Q-type Ca2+ Channels, Zhang, Yun; Chen, YuHang; Bangaru, Saroja D; He, Linling; Abele, Kathryn; Tanabe, Shihori; Kozasa, Tohru; Yang, Jian, 2008
Functional modularity of the beta-subunit of voltage-gated Ca2+ channels, He, Linling; Zhang, Yun; Chen, Yuhang; Yamada, Yoichi; Yang, Jian, 2007
Structural basis of the alpha(1)-beta subunit interaction of voltage-gated Ca2+ channels, Chen, YH; Li, MH; Zhang, Y; He, LL; Yamada, Y; Fitzmaurice, A; Shen, Y; Zhang, HL; Tong, L; Yang, J, 2004

Protein Structure Molecular Breeding Bioinformatics Bioengineering Plant Biology Genetics Developmental Biology Molecular Design

Dongping Lu - Shanghai Jiao Tong University

Mengting Ma - Shanghai Jiao Tong University

Fan Chen - University of Chinese Academy of Sciences

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