Areas of Focus
- Human Tissue Embryology
Work Experience
- 1987.9-1990.10 Assistant at Veterinary University
- 1990.11-1997.10 Lecturer at Veterinary University
- 1997.11-1998.10 Associate Professor at Veterinary University
- 1998.1-2002.9 Postdoctoral Researcher at University of Missouri
- 2002.10-2006.10 Research Assistant Professor at University of Missouri
- 2007.10-Present Professor at Jilin University
Academic Background & Achievements
- 1980.9-1984.7 Bachelor's degree from Sichuan Animal Husbandry and Veterinary College
- 1980.9-1983.7 Master's degree in Basic Veterinary Medicine from Veterinary University
- 1992.9-1995.7 Doctorate in Biological Engineering from Northeast Agricultural University
Publications
- Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, Liangxue Lai, 2022
- CRISPR/Cas9-mediated gene correction in newborn rabbits with hereditary tyrosinemia type I, Liangxue Lai, 2021
- Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing, Liangxue Lai, 2021
- ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, Liangxue Lai, 2020
- Development of a rabbit model of Wiskott-Aldrich syndrome, Liangxue Lai, 2020
- Efficient base editing for multiple genes and loci in pigs using base editors, Liangxue Lai, 2019
- XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, Liangxue Lai, 2018
- Generation of ApoE deficient dogs via combination of embryo injection of CRISPR/Cas9 with somatic cell nuclear transfer, Liangxue Lai, 2018
- Engineering CRISPR /Cpf1 with tRNA promotes genome editing capability in mammalian systems, Liangxue Lai, 2018
- A huntingtin knockin pig model recapitulates features of selective neurodegeneration in huntington's disease, Liangxue Lai, 2018
- CRISPR-induced exon skipping is dependent on premature termination codon mutations, Liangxue Lai, 2018
- Highly efficient RNA-guided base editing in rabbit, Liangxue Lai, 2018
- Cre-dependent cas9-expressing pigs enable efficient in vivo genome editing, Liangxue Lai, 2017
Awards
- 2002: Medical Technology Highest Award from New Era of Science and Technology magazine
- 2002 and 2006: Two research results were ranked in the top 30 of the 100 major scientific news by Discovery magazine
- 2005: Our transgenic green pig photos and text introduction were published in National Geographic magazine
- Outstanding Young Overseas Chinese Fund recipient
- Recipient of the State Council Special Allowance
- Chief Scientist of the 973 Project
