Professor | Liangxue Lai | Asia Growth Partners

Name

Liangxue Lai

Contact Information

lai_liangxue@gibh.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Jilin University
Faculty	Vetrinary Medicine
Academic Background & Achievements	1980.9-1984.7 Bachelor's degree from Sichuan Animal Husbandry and Veterinary College 1980.9-1983.7 Master's degree in Basic Veterinary Medicine from Veterinary University 1992.9-1995.7 Doctorate in Biological Engineering from Northeast Agricultural University
Work Experience	1987.9-1990.10 Assistant at Veterinary University 1990.11-1997.10 Lecturer at Veterinary University 1997.11-1998.10 Associate Professor at Veterinary University 1998.1-2002.9 Postdoctoral Researcher at University of Missouri 2002.10-2006.10 Research Assistant Professor at University of Missouri 2007.10-Present Professor at Jilin University
Awards	2002: Medical Technology Highest Award from New Era of Science and Technology magazine 2002 and 2006: Two research results were ranked in the top 30 of the 100 major scientific news by Discovery magazine 2005: Our transgenic green pig photos and text introduction were published in National Geographic magazine Outstanding Young Overseas Chinese Fund recipient Recipient of the State Council Special Allowance Chief Scientist of the 973 Project

University/Lab Affiliation and Title

Jilin University

Faculty

Vetrinary Medicine

Academic Background & Achievements

1980.9-1984.7 Bachelor's degree from Sichuan Animal Husbandry and Veterinary College
1980.9-1983.7 Master's degree in Basic Veterinary Medicine from Veterinary University
1992.9-1995.7 Doctorate in Biological Engineering from Northeast Agricultural University

Work Experience

Awards

2002: Medical Technology Highest Award from New Era of Science and Technology magazine
2002 and 2006: Two research results were ranked in the top 30 of the 100 major scientific news by Discovery magazine
2005: Our transgenic green pig photos and text introduction were published in National Geographic magazine
Outstanding Young Overseas Chinese Fund recipient
Recipient of the State Council Special Allowance
Chief Scientist of the 973 Project

Areas of Focus	Human Tissue Embryology
Publications	Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, Liangxue Lai, 2022 CRISPR/Cas9-mediated gene correction in newborn rabbits with hereditary tyrosinemia type I, Liangxue Lai, 2021 Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing, Liangxue Lai, 2021 ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, Liangxue Lai, 2020 Development of a rabbit model of Wiskott-Aldrich syndrome, Liangxue Lai, 2020 Efficient base editing for multiple genes and loci in pigs using base editors, Liangxue Lai, 2019 XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, Liangxue Lai, 2018 Generation of ApoE deficient dogs via combination of embryo injection of CRISPR/Cas9 with somatic cell nuclear transfer, Liangxue Lai, 2018 Engineering CRISPR /Cpf1 with tRNA promotes genome editing capability in mammalian systems, Liangxue Lai, 2018 A huntingtin knockin pig model recapitulates features of selective neurodegeneration in huntington's disease, Liangxue Lai, 2018 CRISPR-induced exon skipping is dependent on premature termination codon mutations, Liangxue Lai, 2018 Highly efficient RNA-guided base editing in rabbit, Liangxue Lai, 2018 Cre-dependent cas9-expressing pigs enable efficient in vivo genome editing, Liangxue Lai, 2017

Areas of Focus

Human Tissue Embryology

Publications

Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, Liangxue Lai, 2022
CRISPR/Cas9-mediated gene correction in newborn rabbits with hereditary tyrosinemia type I, Liangxue Lai, 2021
Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing, Liangxue Lai, 2021
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, Liangxue Lai, 2020
Development of a rabbit model of Wiskott-Aldrich syndrome, Liangxue Lai, 2020
Efficient base editing for multiple genes and loci in pigs using base editors, Liangxue Lai, 2019
XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, Liangxue Lai, 2018
Generation of ApoE deficient dogs via combination of embryo injection of CRISPR/Cas9 with somatic cell nuclear transfer, Liangxue Lai, 2018
Engineering CRISPR /Cpf1 with tRNA promotes genome editing capability in mammalian systems, Liangxue Lai, 2018
A huntingtin knockin pig model recapitulates features of selective neurodegeneration in huntington's disease, Liangxue Lai, 2018
CRISPR-induced exon skipping is dependent on premature termination codon mutations, Liangxue Lai, 2018
Highly efficient RNA-guided base editing in rabbit, Liangxue Lai, 2018
Cre-dependent cas9-expressing pigs enable efficient in vivo genome editing, Liangxue Lai, 2017

Human Tissue Embryology Development Cell Biology Research Education Science Health

Guan Wutai - South China Agricultural University

Chong Wang - South China Agricultural University

Nie Qinghua - South China Agricultural University

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