Areas of Focus
- 人体组织胚胎学
Work Experience
- 1987.9-1990.10,兽医大学助教
- 1990.11-1997.10,兽医大学讲师
- 1997.11-1998.10,兽医大学副教授
- 1998.1-2002.9,美国密苏里大学博士后
- 2002.10-2006.10,美国密苏里大学研究助理教授
- 2007.10至今,吉林大学教授博导
Academic Background & Achievements
- 1980.9-1984.7,四川畜牧兽医学院,本科学习
- 1980.9-1983.7,兽医大学,获得基础兽医学硕士
- 1992.9-1995.7,东北农业大学,获得生物工程博士学位
Publications
- Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9, 赖良学, 2022
- CRISPR/Cas9-mediated gene correction in newborn rabbits with hereditary tyrosinemia type I, 赖良学, 2021
- Generation of permanent neonatal diabetes mellitus dogs with glucokinase point mutations through base editing, 赖良学, 2021
- ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems, 赖良学, 2020
- Development of a rabbit model of Wiskott-Aldrich syndrome, 赖良学, 2020
- Efficient base editing for multiple genes and loci in pigs using base editors, 赖良学, 2019
- XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer, 赖良学, 2018
- Generation of ApoE deficient dogs via combination of embryo injection of CRISPR/Cas9 with somatic cell nuclear transfer, 赖良学, 2018
- Engineering CRISPR /Cpf1 with tRNA promotes genome editing capability in mammalian systems, 赖良学, 2018
- A huntingtin knockin pig model recapitulates features of selective neurodegeneration in huntington's disease, 赖良学, 2018
- CRISPR-induced exon skipping is dependent on premature termination codon mutations, 赖良学, 2018
- Highly efficient RNA-guided base editing in rabbit, 赖良学, 2018
- Cre-dependent cas9-expressing pigs enable efficient in vivo genome editing, 赖良学, 2017
Awards
- 2002年,《科技新时代》杂志“医学技术最高奖”获得者
- 2002年和2006年,两项研究成果被《发现》杂志评为世界100大科技新闻前30位
- 2005年,我们的转基因绿猪照片和文字介绍被刊登在《国家地理杂志》
- 中国海外杰出青年基金获得者
- 国务院特殊津贴获得者
- 973项目首席科学家