Professor | Qinghua Tao | Asia Growth Partners

Name	Qinghua Tao
Contact Information	qhtaolab@mail.tsinghua.edu.cn
Language ability	Chinese, English
Province	Beijing

Name

Qinghua Tao

Contact Information

qhtaolab@mail.tsinghua.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	1988-1992 Bachelor in Genetics, Sichuan University 1995-2000 PhD in Developmental Biology, Shanghai Institute for Biological Sciences, CAS
Work Experience	2000-2008 Postdoctoral Researcher, Research Assistant, Cincinnati Children's Hospital Medical Center, USA 2008-present Professor, School of Life Sciences, Tsinghua University

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

1988-1992 Bachelor in Genetics, Sichuan University
1995-2000 PhD in Developmental Biology, Shanghai Institute for Biological Sciences, CAS

Work Experience

2000-2008 Postdoctoral Researcher, Research Assistant, Cincinnati Children's Hospital Medical Center, USA
2008-present Professor, School of Life Sciences, Tsinghua University

Areas of Focus	Molecular mechanisms of cell fate determination and differentiation in early vertebrate embryogenesis Cross-generational regulatory mechanisms in embryonic development Metabolic regulation and self-organization in fertilized eggs and early embryos Mechanisms of directed differentiation of embryonic pluripotent cells induced by growth factors like Wnt, TGF-β, FGF
Publications	Lysosomal degradation of the maternal dorsal determinant Hwa to safeguard dorsal body axis formation, Zhu XC, Wang P, Wei JL, Li YY, Zhai JY, Zheng TR, Tao QH, 2021 The Cytokine FAM3B/PANDER is an FGFR Ligand that Promotes Posterior Development in Xenopus, Zhang FF, Zhuc XC, Wang P, He Q, Huang HM, Zheng TR, Li YY, Jia H, Xu LP, Zhao HX, Colozza G, Tao QH, De Robertis EM, Ding Y, 2021 Maternal Huluwa Dictates the Embryonic Body Axis through b-catenin in Vertebrates, Yan L, Chen J, Zhu XC, Sun JW, Wu XT, Shen WM, Zhang WY, Tao QH, Meng AM, 2018 KDM3A-mediated dimethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis, Lin H, Zhu XC, Chen G, Song L, Gao L, Khand AA, Chen Y, Lin GF, Tao QH, 2017 The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus, Zhu XC, Xing R, Tan RB, Dai RY, Tao QH, 2017 A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function, Gao L, Zhu XC, Chen G, Ma X, Zhang Y, Khand A, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao QH, 2016 The MLL/Setd1b methyltransferase is required for the Spemann’s organizer gene activation in Xenopus, Lin H, Min Z, Tao QH, 2016 NEDD4L regulates convergent extension movements in Xenopus embryos via Dishevelled-mediated non-canonical Wnt signaling, Zhang Y, Ding Y, Chen YG, Tao QH, 2014 HECT Domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting Dishevelled for proteasomal degradation, Ding Y, Zhang Y, Xu C, Tao QH* and Chen YG*, 2013 Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos, Tao QH, Yokota C, Puck H, Kofron M, Birsoy B, Dong Y, Asashima M, Wylie C, Lin X and Heasman J., 2005

Areas of Focus

Molecular mechanisms of cell fate determination and differentiation in early vertebrate embryogenesis
Cross-generational regulatory mechanisms in embryonic development
Metabolic regulation and self-organization in fertilized eggs and early embryos
Mechanisms of directed differentiation of embryonic pluripotent cells induced by growth factors like Wnt, TGF-β, FGF

Publications

Lysosomal degradation of the maternal dorsal determinant Hwa to safeguard dorsal body axis formation, Zhu XC, Wang P, Wei JL, Li YY, Zhai JY, Zheng TR, Tao QH*, 2021
The Cytokine FAM3B/PANDER is an FGFR Ligand that Promotes Posterior Development in Xenopus, Zhang FF, Zhuc XC, Wang P, He Q, Huang HM, Zheng TR, Li YY, Jia H, Xu LP, Zhao HX, Colozza G, Tao QH*, De Robertis EM*, Ding Y*, 2021
Maternal Huluwa Dictates the Embryonic Body Axis through b-catenin in Vertebrates, Yan L, Chen J, Zhu XC, Sun JW, Wu XT, Shen WM, Zhang WY, Tao QH*, Meng AM*, 2018
KDM3A-mediated dimethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis, Lin H, Zhu XC, Chen G, Song L, Gao L, Khand AA, Chen Y, Lin GF*, Tao QH*, 2017
The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus, Zhu XC, Xing R, Tan RB, Dai RY, Tao QH, 2017
A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT function, Gao L, Zhu XC, Chen G, Ma X, Zhang Y, Khand A, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao QH*, 2016
The MLL/Setd1b methyltransferase is required for the Spemann’s organizer gene activation in Xenopus, Lin H, Min Z, Tao QH*, 2016
NEDD4L regulates convergent extension movements in Xenopus embryos via Dishevelled-mediated non-canonical Wnt signaling, Zhang Y, Ding Y, Chen YG*, Tao QH*, 2014
HECT Domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting Dishevelled for proteasomal degradation, Ding Y, Zhang Y, Xu C, Tao QH* and Chen YG*, 2013
Maternal Wnt11 activates the canonical Wnt signaling pathway required for axis formation in Xenopus embryos, Tao QH, Yokota C, Puck H, Kofron M, Birsoy B, Dong Y, Asashima M, Wylie C, Lin X and Heasman J., 2005

Genomics Proteomics Molecular Biology Genetics Cell Fate Differentiation Embryogenesis Congenital Diseases Developmental Outcomes Growth Factors

Xudong Guo - Tongji University

Jing Xie - Tongji University

Yong Zhang - Tongji University

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