Areas of Focus
- Tumor and immune metabolism
Work Experience
- 2008-2013 - University of Pennsylvania School of Medicine - Postdoctoral Researcher
- 2013-2014 - University of Pennsylvania School of Medicine - Research Associate
- 2014-2021 - Tsinghua University School of Life Sciences - Assistant Professor
- 2021- - Tsinghua University School of Life Sciences - Associate Professor
- 2020- - Tsinghua-Peking Joint Center for Life Sciences - Principal Investigator
Academic Background & Achievements
- 1999-2003 Bachelor: Anhui University, Biotechnology
- 2003-2008 PhD: University of Science and Technology of China, Molecular and Cell Biology
- Postdoctoral Researcher at University of Pennsylvania School of Medicine
Publications
- p53 suppresses lipid droplet-fueled tumorigenesis through phosphatidylcholine, Xu X, Wang J, Xu L, Li P, Jiang P, 2024
- AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis, Chen T, Xie S, Cheng J, Zhao Q, Wu H, Jiang P, Du W, 2024
- p53 promotes antiviral innate immunity by driving hexosamine metabolism, Xia W, Jiang P, 2024
- Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment, Cheng J, Yan J, Liu Y, Shi J, Wang H, Zhou H, Zhou Y, Zhang T, Zhao L, Meng X, Gong H, Zhang X, Zhu H, Jiang P, 2023
- Fumarate suppresses B-cell activation and function through direct inactivation of LYN, Cheng J, Liu Y, Yan J, Zhao L, Zhou Y, Shen X, Chen Y, Meng X, Zhang X, Jiang P, 2022
- Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate, Zhao M, Yao P, Mao Y, Wu J, Wang W, Geng C, Cheng J, Du W, Jiang P, 2022
- Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses, Mao Y, Shi D, Li G, Jiang P, 2022
- p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage, Wu J, Li G, Li L, Jiang P, 2021
- Asparagine enhances LCK signalling to potentiate CD8+ T cell-activation and anti-tumour responses, Wu J, Li G, Li L, Li D, Dong Z, Jiang P, 2021
- p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival, Deng L, Yao P, Li L, Ji F, Zhao S, Xu C, Lan X, Jiang P, 2020
- p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis, Li L, Mao Y, Zhao L, Li L, Wu J, Zhao M, Du W, Yu L, Jiang P, 2019
- TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation, Li L, Li L, Li W, Chen T, Bin Zou, Zhao L, Wang H, Wang X, Xu L, Liu X, Wang D, Li B, Mak TW, Du W, Yang X, Jiang P, 2018
- TAp73 enhances the pentose phosphate pathway and supports cell proliferation, Du W, Jiang P, Mancuso A, Stonestrom A, Brewer M, Minn AJ, Mak TW, Wu M, Yang X, 2013
- Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence, Jiang P, Du W, Wang X, Mancuso A, Gao X, Wu M, Yang X, 2013
- p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase, Jiang P, Du W, Wang X, Mancuso A, Gao X, Wu M, Yang X, 2011
