Areas of Focus
- High-resolution cryo-electron tomography (cryo-ET) methods
- Structural and functional studies of emerging enveloped viruses
Work Experience
- 2018-Present - Tsinghua University, School of Life Sciences - Associate Professor
- 2018-Present - Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology - Researcher
- 2017-2018 - University of Oxford, Structural Biology Center (STRUBI) - Senior Research Associate
- 2013-2017 - University of Oxford, Structural Biology Center (STRUBI) - Postdoctoral Researcher
- 2009-2012 - University of Göttingen, Department of Biophysics - PhD Candidate
Academic Background & Achievements
- 2009-2012 PhD: University of Göttingen, Department of Biophysics
- 2006-2008 Master's: University of Stuttgart, Department of Physics
- 2002-2006 Bachelor's: Wuhan University, Department of Applied Physics
Publications
- In situ architecture and membrane fusion of SARS-CoV-2 Delta variant, Sai Li et al., 2023
- Toward Atomistic Models of Intact SARS-CoV-2 via Martini Coarse-Grained Molecular Dynamics Simulations, Sai Li et al., 2023
- Cryo-electron tomography: the resolution revolution and a surge of in situ virological discoveries, Sai Li et al., 2023
- Cryo-electron tomography of enveloped viruses, Sai Li, 2022
- Site-specific steric control of SARS-CoV-2 spike glycosylation, Sai Li et al., 2021
- Molecular architecture of the SARS-CoV-2 virus, Sai Li et al., 2020
- PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins, Sai Li et al., 2020
- Packaging and delivering enzymes by amorphous metal-organic frameworks, Sai Li et al., 2019