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Sai Li
sai@mail.tsinghua.edu.cn
English, Chinese, German
Beijing
Tsinghua University
Life Sciences
  • 2002-2006 Bachelor: Wuhan University, Applied Physics
  • 2006-2008 Master: University of Stuttgart, Physics
  • 2009-2012 PhD: University of Göttingen, Biophysics
  • 2013-2017 - University of Oxford, STRUBI, Postdoctoral Researcher
  • 2017-2018 - University of Oxford, STRUBI, Senior Research Associate
  • 2018-present - Tsinghua University, Assistant Professor/Associate Professor
  • 2018-present - Joint Center for Life Sciences, Tsinghua-Peking, Researcher
High-resolution cryo-electron tomography (cryo-ET) methods
Structural and functional studies of emerging enveloped viruses
  • In situ architecture and membrane fusion of SARS-CoV-2 Delta variant, Sai Li et al., 2023
  • Toward Atomistic Models of Intact SARS-CoV-2 via Martini Coarse-Grained Molecular Dynamics Simulations, Sai Li et al., 2023
  • Cryo-electron tomography: the resolution revolution and a surge of in situ virological discoveries, Sai Li et al., 2023
  • Cryo-electron tomography of enveloped viruses, Sai Li, 2022
  • Site-specific steric control of SARS-CoV-2 spike glycosylation, Sai Li et al., 2021
  • Molecular architecture of the SARS-CoV-2 virus, Sai Li et al., 2020
  • PSGL-1 inhibits HIV-1 infection by restricting actin dynamics and sequestering HIV envelope proteins, Sai Li et al., 2020
  • Packaging and delivering enzymes by amorphous metal-organic frameworks, Sai Li et al., 2019
Cryo-Et High-Resolution Structural Biology Virus Cell Imaging Molecular Structure In Situ Clem Cryo-Fib Biophysics

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