Areas of Focus
- Genome regulation events at various levels, focusing on R-loop biology and genome regulation
Work Experience
- 2022-Present Associate Professor, Tsinghua University, School of Life Sciences
- 2014-2021 Assistant Professor, Tsinghua University, School of Life Sciences
- 2014-Present Researcher, Tsinghua-Peking Joint Center for Life Sciences
- 2009-2014 Postdoctoral Researcher, John Innes Centre, Norwich, UK
Academic Background & Achievements
- 2004-2009 PhD: Huazhong Agricultural University, College of Life Sciences
- 2000-2004 Bachelor: Huazhong Agricultural University, College of Life Sciences
Publications
- Primase promotes the competition between transcription and replication on the same template strand resulting in DNA damage, Weifeng Zhang, Zhuo Yang, Wenjie Wang, Qianwen Sun, 2024
- DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis, Qin Li, Jincong Zhou, Shuai Li, Weifeng Zhang, Yingxue Du, Kuan Li, Yingxiang Wang, Qianwen Sun, 2023
- DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis, Jincong Zhou, Xue Lei, Sarfraz Shafiq, Weifeng Zhang, Qin Li, Kuan Li, Jiafu Zhu, Zhicheng Dong, Xin-Jian He, Qianwen Sun, 2023
- DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms, Wei Xu, Chao Liu, Zhe Zhang, Changbin Sun, Qin Li, Kuan Li, Hui Jiang, Wei Li, Qianwen Sun, 2023
- R-loopAtlas: An integrated R-loop resource from 254 plant species sustained by a deep-learning-based tool, Kuan Li, Zhenzhen Wu, Jincong Zhou, Wei Xu, Ling Li, Chao Liu, Wei Li, Chengjun Zhang, Qianwen Sun, 2023
- Intragenic tRNA-promoted R-loops orchestrate transcription interference for plant oxidative stress responses, Liu K, Sun Q, 2021
- Mitochondrial RNase H1 activity regulates R-loop homeostasis to maintain genome integrity and enable early embryogenesis in Arabidopsis, Cheng L, Wang W, Yao Y, Sun Q, 2021
- RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts, Wang W, Li K, Yang Z, Hou Q, Zhao W W, Sun Q, 2021
- RHON1 Co-transcriptionally Resolves R-Loops for Arabidopsis Chloroplast Genome Maintenance, Yang Z, Li M, Sun Q, 2020
- The R-loop atlas of Arabidopsis development and responses to environmental stimuli, Xu W, Li K, Li S, Hou Q, Zhang Y, Liu K, Sun Q, 2020
- Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation, Zhao S, Cheng L, Gao Y, Zhang B, Zheng X, Wang L, Li P, Sun Q, Li H, 2019
- RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts, Yang Z, Hou Q, Cheng L, Xu W, Hong Y, Li S, Sun Q, 2017
- The R-loop is a common chromatin feature of the Arabidopsis genome, Xu W, Xu H, Li K, Fan Y, Liu Y, Yang X, Sun Q, 2017
- R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus, Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C, 2013
