Professor | Qianwen Sun | Asia Growth Partners

Name	Qianwen Sun
Contact Information	sunqianwen@mail.tsinghua.edu.cn
Language ability	English, Chinese
Province	Beijing

Name

Qianwen Sun

Contact Information

sunqianwen@mail.tsinghua.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Tsinghua University
Faculty	Life Sciences
Academic Background & Achievements	2004-2009 PhD: Huazhong Agricultural University, College of Life Sciences 2000-2004 Bachelor: Huazhong Agricultural University, College of Life Sciences
Work Experience	2022-Present Associate Professor, Tsinghua University, School of Life Sciences 2014-2021 Assistant Professor, Tsinghua University, School of Life Sciences 2014-Present Researcher, Tsinghua-Peking Joint Center for Life Sciences 2009-2014 Postdoctoral Researcher, John Innes Centre, Norwich, UK

University/Lab Affiliation and Title

Tsinghua University

Faculty

Life Sciences

Academic Background & Achievements

2004-2009 PhD: Huazhong Agricultural University, College of Life Sciences
2000-2004 Bachelor: Huazhong Agricultural University, College of Life Sciences

Work Experience

2022-Present Associate Professor, Tsinghua University, School of Life Sciences
2014-2021 Assistant Professor, Tsinghua University, School of Life Sciences
2014-Present Researcher, Tsinghua-Peking Joint Center for Life Sciences
2009-2014 Postdoctoral Researcher, John Innes Centre, Norwich, UK

Areas of Focus	Genome regulation events at various levels, focusing on R-loop biology and genome regulation
Publications	Primase promotes the competition between transcription and replication on the same template strand resulting in DNA damage, Weifeng Zhang, Zhuo Yang, Wenjie Wang, Qianwen Sun, 2024 DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis, Qin Li, Jincong Zhou, Shuai Li, Weifeng Zhang, Yingxue Du, Kuan Li, Yingxiang Wang, Qianwen Sun, 2023 DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis, Jincong Zhou, Xue Lei, Sarfraz Shafiq, Weifeng Zhang, Qin Li, Kuan Li, Jiafu Zhu, Zhicheng Dong, Xin-Jian He, Qianwen Sun, 2023 DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms, Wei Xu, Chao Liu, Zhe Zhang, Changbin Sun, Qin Li, Kuan Li, Hui Jiang, Wei Li, Qianwen Sun, 2023 R-loopAtlas: An integrated R-loop resource from 254 plant species sustained by a deep-learning-based tool, Kuan Li, Zhenzhen Wu, Jincong Zhou, Wei Xu, Ling Li, Chao Liu, Wei Li, Chengjun Zhang, Qianwen Sun, 2023 Intragenic tRNA-promoted R-loops orchestrate transcription interference for plant oxidative stress responses, Liu K, Sun Q, 2021 Mitochondrial RNase H1 activity regulates R-loop homeostasis to maintain genome integrity and enable early embryogenesis in Arabidopsis, Cheng L, Wang W, Yao Y, Sun Q, 2021 RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts, Wang W, Li K, Yang Z, Hou Q, Zhao W W, Sun Q, 2021 RHON1 Co-transcriptionally Resolves R-Loops for Arabidopsis Chloroplast Genome Maintenance, Yang Z, Li M, Sun Q, 2020 The R-loop atlas of Arabidopsis development and responses to environmental stimuli, Xu W, Li K, Li S, Hou Q, Zhang Y, Liu K, Sun Q, 2020 Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation, Zhao S, Cheng L, Gao Y, Zhang B, Zheng X, Wang L, Li P, Sun Q, Li H, 2019 RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts, Yang Z, Hou Q, Cheng L, Xu W, Hong Y, Li S, Sun Q, 2017 The R-loop is a common chromatin feature of the Arabidopsis genome, Xu W, Xu H, Li K, Fan Y, Liu Y, Yang X, Sun Q, 2017 R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus, Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C, 2013

Areas of Focus

Genome regulation events at various levels, focusing on R-loop biology and genome regulation

Publications

Primase promotes the competition between transcription and replication on the same template strand resulting in DNA damage, Weifeng Zhang, Zhuo Yang, Wenjie Wang, Qianwen Sun, 2024
DNA polymerase ε harmonizes topological states and R-loops formation to maintain genome integrity in Arabidopsis, Qin Li, Jincong Zhou, Shuai Li, Weifeng Zhang, Yingxue Du, Kuan Li, Yingxiang Wang, Qianwen Sun, 2023
DDM1-mediated R-loop resolution and H2A.Z exclusion facilitates heterochromatin formation in Arabidopsis, Jincong Zhou, Xue Lei, Sarfraz Shafiq, Weifeng Zhang, Qin Li, Kuan Li, Jiafu Zhu, Zhicheng Dong, Xin-Jian He, Qianwen Sun, 2023
DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms, Wei Xu, Chao Liu, Zhe Zhang, Changbin Sun, Qin Li, Kuan Li, Hui Jiang, Wei Li, Qianwen Sun, 2023
R-loopAtlas: An integrated R-loop resource from 254 plant species sustained by a deep-learning-based tool, Kuan Li, Zhenzhen Wu, Jincong Zhou, Wei Xu, Ling Li, Chao Liu, Wei Li, Chengjun Zhang, Qianwen Sun, 2023
Intragenic tRNA-promoted R-loops orchestrate transcription interference for plant oxidative stress responses, Liu K, Sun Q, 2021
Mitochondrial RNase H1 activity regulates R-loop homeostasis to maintain genome integrity and enable early embryogenesis in Arabidopsis, Cheng L, Wang W, Yao Y, Sun Q, 2021
RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts, Wang W, Li K, Yang Z, Hou Q, Zhao W W, Sun Q, 2021
RHON1 Co-transcriptionally Resolves R-Loops for Arabidopsis Chloroplast Genome Maintenance, Yang Z, Li M, Sun Q, 2020
The R-loop atlas of Arabidopsis development and responses to environmental stimuli, Xu W, Li K, Li S, Hou Q, Zhang Y, Liu K, Sun Q, 2020
Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation, Zhao S, Cheng L, Gao Y, Zhang B, Zheng X, Wang L, Li P, Sun Q, Li H, 2019
RNase H1 Cooperates with DNA Gyrases to Restrict R-Loops and Maintain Genome Integrity in Arabidopsis Chloroplasts, Yang Z, Hou Q, Cheng L, Xu W, Hong Y, Li S, Sun Q, 2017
The R-loop is a common chromatin feature of the Arabidopsis genome, Xu W, Xu H, Li K, Fan Y, Liu Y, Yang X, Sun Q, 2017
R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus, Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C, 2013

Genome Regulation R-Loop Biology Chromatin Structure Transcription Regulation Genome Integrity Molecular Mechanisms Arabidopsis Bacteria Yeast

Yue Lou - Shanghai Normal University

Zhilei Mao - Shanghai Normal University

Wenxiu Wang - Shanghai Normal University

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