Professor | Fangwei Wang | Asia Growth Partners

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Name	Fangwei Wang
Contact Information	fwwang@zju.edu.cn
Language ability	Chinese, English, Japanese
Province	Zhejiang

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Name

Fangwei Wang

Contact Information

fwwang@zju.edu.cn

Language ability

Chinese, English, Japanese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Life Sciences
Academic Background & Achievements	1993 - 1997, Bachelor's Degree: Zhejiang University 1999 - 2002, Master's Degree: Zhejiang University 2003 - 2006, PhD: Tokyo University of Agriculture and Technology 2006 - 2011, Postdoctoral Research: Harvard Medical School
Work Experience	1997 - 2003, Teacher at Zhejiang University 2011 - 2013, Lecturer at Harvard Medical School From November 2012, Professor and Doctoral Supervisor at Zhejiang University
Awards	2010, BWH Research Excellence Award, Harvard Medical School 2011, Outstanding Chinese Life Scientist of the Year, Harvard Medical School 2012, National High-level Personnel of Special Support Program 2013, Distinguished Young Scholar, Zhejiang Province 2015, Newton Advanced Fellowship, Royal Society, UK 2020, National Science Fund for Distinguished Young Scholars 2020, Outstanding Research Award, Zhejiang University 2023, Second Class Prize in Natural Science, Zhejiang Province (First Author)

University/Lab Affiliation and Title

Zhejiang University

Faculty

Life Sciences

Academic Background & Achievements

1993 - 1997, Bachelor's Degree: Zhejiang University
1999 - 2002, Master's Degree: Zhejiang University
2003 - 2006, PhD: Tokyo University of Agriculture and Technology
2006 - 2011, Postdoctoral Research: Harvard Medical School

Work Experience

1997 - 2003, Teacher at Zhejiang University
2011 - 2013, Lecturer at Harvard Medical School
From November 2012, Professor and Doctoral Supervisor at Zhejiang University

Awards

2010, BWH Research Excellence Award, Harvard Medical School
2011, Outstanding Chinese Life Scientist of the Year, Harvard Medical School
2012, National High-level Personnel of Special Support Program
2013, Distinguished Young Scholar, Zhejiang Province
2015, Newton Advanced Fellowship, Royal Society, UK
2020, National Science Fund for Distinguished Young Scholars
2020, Outstanding Research Award, Zhejiang University
2023, Second Class Prize in Natural Science, Zhejiang Province (First Author)

Areas of Focus	Cell cycle and mitosis Chromosome biology Genomic stability
Publications	Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis, Fangwei Wang, 2010 A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis, Fangwei Wang, 2011 Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation, Fangwei Wang, 2012 Histone modifications and mitosis: countermarks, landmarks and bookmarks, Fangwei Wang, 2013 Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis, Fangwei Wang, 2014 The N-terminal non-kinase-domain-mediated binding of Haspin to Pds5B protects centromeric cohesion in mitosis, Fangwei Wang, 2017 A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion, Fangwei Wang, 2018 HP1 links centromeric heterochromatin to centromere cohesion in mammals, Fangwei Wang, 2018 WAC promotes Polo-like kinase 1 activation for timely mitotic entry, Fangwei Wang, 2018 A positive feedback mechanism ensures proper assembly of the functional inner centromere during mitosis in human cells, Fangwei Wang, 2019 Aurora B kinase activity-dependent and -independent functions of the chromosomal passenger complex in regulating sister chromatid cohesion, Fangwei Wang, 2019 Histone H2A phosphorylation recruits topoisomerase IIα to centromeres to safeguard genomic stability, Fangwei Wang, 2020 Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation, Fangwei Wang, 2020 Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation, Fangwei Wang The cGAS-STING pathway: a therapeutic target in chromosomally unstable cancers, Fangwei Wang

Areas of Focus

Cell cycle and mitosis
Chromosome biology
Genomic stability

Publications

Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis, Fangwei Wang, 2010
A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis, Fangwei Wang, 2011
Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation, Fangwei Wang, 2012
Histone modifications and mitosis: countermarks, landmarks and bookmarks, Fangwei Wang, 2013
Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis, Fangwei Wang, 2014
The N-terminal non-kinase-domain-mediated binding of Haspin to Pds5B protects centromeric cohesion in mitosis, Fangwei Wang, 2017
A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion, Fangwei Wang, 2018
HP1 links centromeric heterochromatin to centromere cohesion in mammals, Fangwei Wang, 2018
WAC promotes Polo-like kinase 1 activation for timely mitotic entry, Fangwei Wang, 2018
A positive feedback mechanism ensures proper assembly of the functional inner centromere during mitosis in human cells, Fangwei Wang, 2019
Aurora B kinase activity-dependent and -independent functions of the chromosomal passenger complex in regulating sister chromatid cohesion, Fangwei Wang, 2019
Histone H2A phosphorylation recruits topoisomerase IIα to centromeres to safeguard genomic stability, Fangwei Wang, 2020
Centromere-localized Aurora B kinase is required for the fidelity of chromosome segregation, Fangwei Wang, 2020
Bub1 and CENP-U redundantly recruit Plk1 to stabilize kinetochore-microtubule attachments and ensure accurate chromosome segregation, Fangwei Wang
The cGAS-STING pathway: a therapeutic target in chromosomally unstable cancers, Fangwei Wang

Cell Division Cancer Chromosome Segregation Mitotic Regulation Protein Kinases Histone Modifications Centromere Dynamics Cohesion Chromosomal Instability Therapeutic Targets

Li Yanli - Shanghai University

Jing Hu - Peking University

Chunguang Wang - Tongji University

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