Upload Avatar (500 x 500)
Haiyang Dong
Life Science
Zhejiang University
Zhejiang
Language: Chinese, English
Rna
Splicing
Crispr/Cas9
Gene Editing
High-Throughput Sequencing
Evolutionary Conservation
Molecular Biology
Cell Biology
Drosophila Genetics
Neuronal Wiring
Areas of Focus
- RNA Biology
Work Experience
- 2023.12-Present - Zhejiang University, School of Life Sciences, Hundred Talents Program Researcher
- 2021.07-2023.12 - Zhejiang University, School of Life Sciences, Postdoctoral Researcher
Academic Background & Achievements
- 2015-2021 PhD in Biochemistry and Molecular Biology, Zhejiang University
- Recipient of national and provincial grants for young scientists
Publications
- A systematic CRISPR screen reveals redundant and specific roles for Dscam1 isoform diversity in neuronal wiring, Haiyang Dong et al., 2023
- Confluence and convergence of Dscam and Pcdh cell-recognition codes, Haiyang Dong et al.
- Emerging progress of RNA-based anti-tumor therapeutics, Haiyang Dong et al., 2023
- Cis mutagenesis in vivo reveals extensive noncanonical functions of Dscam1 isoforms in neuronal wiring, Haiyang Dong et al., 2023
- Hidden RNA pairings counteract the 'first-come, first-served' splicing principle to drive stochastic choice in Dscam1 splice variants, Haiyang Dong et al., 2022
- Self-avoidance alone does not explain the function of Dscam1 in mushroom body axonal wiring, Haiyang Dong et al.
- Trans-splicing facilitated by RNA pairing greatly expands sDscam isoform diversity but not homophilic binding specificity, Haiyang Dong et al., 2022
- Intron-targeted mutagenesis reveals roles for Dscam1 RNA pairing architecture-driven splicing bias in neuronal wiring, Haiyang Dong et al.
- Complex RNA Secondary Structures Mediate Mutually Exclusive Splicing of Coleoptera Dscam1, Haiyang Dong et al., 2021
- Mutually exclusive alternative splicing of pre-mRNAs, Haiyang Dong et al., 2018
- A chelicerate-specific burst of nonclassical Dscam diversity, Haiyang Dong et al., 2018
- Competing RNA pairings in complex alternative splicing of a 3' variable region, Haiyang Dong et al., 2018
