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Changtao Jiang
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Gut Microbiota
Metabolic Disease
Pathogenesis
Bile Acids
Nicotine
Ceramides
Isozymes
Dpp4
Intestinal Targets
Therapeutics
Areas of Focus
- Gut microbiota and metabolic disease pathogenesis
Work Experience
- Professor at Peking University, School of Basic Medical Sciences
- Vice Dean at Peking University, School of Basic Medical Sciences
Academic Background & Achievements
- Recipient of the National Science Fund for Distinguished Young Scholars
- Recipient of the Science Exploration Award
Publications
- Microbial-host-isozyme analyses reveal microbial DPP4 as a potential antidiabetic target, Jiang CT et al., 2023
- Gut bacteria alleviate smoking-related NASH by degrading gut nicotine, Jiang CT et al., 2022
- Intestinal hypoxia-inducible factor 2α regulates lactate levels to shape the gut microbiome and alter thermogenesis, Jiang CT et al., 2021
- Gut microbiota and intestinal FXR mediate the clinical benefits of metformin, Jiang CT et al., 2018
- Adipocyte hypoxia-inducible factor 2α suppresses atherosclerosis by promoting adipose ceramide catabolism, Jiang CT et al., 2019
- Suppressing the intestinal farnesoid X receptor/sphingomyelin phosphodiesterase 3 axis decreases atherosclerosis, Jiang CT et al., 2021
- Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism, Jiang CT et al., 2021
- Gut microbiota-bile acid-interleukin-22 axis orchestrates polycystic ovary syndrome, Jiang CT et al., 2019
- Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis, Jiang CT et al., 2017
- Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance, Jiang CT et al., 2021
Awards
- Science Exploration Award
- China Youth Science and Technology Award
- Shulan Medical Youth Award
- CADA Young Scientist Award
- Mao Yisheng Beijing Youth Science and Technology Award
