Professor | Yuxiang Wang | Asia Growth Partners

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Name	Yuxiang Wang
Contact Information	yuxiang_wang@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Yuxiang Wang

Contact Information

yuxiang_wang@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Awards	Pujiang Talent Plan (2020)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Awards

Pujiang Talent Plan (2020)

Areas of Focus	Pathogenesis and treatment of brain glioma Mechanisms and gene therapy of rare neuromuscular diseases
Publications	Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas, Wang Y, Wild AT, Turcan S, Wu W, Sigel C, Klimtra D, Ma X, Gong Y, Holland EC, Huse JT, Chan TA, 2020 G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma, Wang Y, Yang J, Wild AT, Wu W, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, and Huse JT, 2019 Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence, Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, 2018 Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling, Danussi C, Bose P, Parthasarathy PT, Silberman PC, Arnam JSV, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang P, Creighton CJ, Deneen B, Miller CY, Picketts DJ, Huse JT, 2018 Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC–ERK1/2–mTOR signaling pathway, Wang Y, Zhu L, Kuokkanen S, and Pollard JW, 2015 GSK-3β mediates in the progesterone inhibition of estrogen induced cyclin D2 nuclear localization and cell proliferation in cyclin D1−/− mouse uterine epithelium, Wang Y, Feng H, Bi C, Zhu L, Pollard JW, Chen B, 2007

Areas of Focus

Pathogenesis and treatment of brain glioma
Mechanisms and gene therapy of rare neuromuscular diseases

Publications

Targeting therapeutic vulnerabilities with PARP inhibition and radiation in IDH-mutant gliomas and cholangiocarcinomas, Wang Y, Wild AT, Turcan S, Wu W, Sigel C, Klimtra D, Ma X, Gong Y, Holland EC, Huse JT, Chan TA, 2020
G-quadruplex DNA drives genomic instability and represents a targetable molecular abnormality in ATRX-deficient malignant glioma, Wang Y, Yang J, Wild AT, Wu W, Shah R, Danussi C, Riggins GJ, Kannan K, Sulman EP, Chan TA, and Huse JT, 2019
Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence, Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, 2018
Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling, Danussi C, Bose P, Parthasarathy PT, Silberman PC, Arnam JSV, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang P, Creighton CJ, Deneen B, Miller CY, Picketts DJ, Huse JT, 2018
Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC–ERK1/2–mTOR signaling pathway, Wang Y, Zhu L, Kuokkanen S, and Pollard JW, 2015
GSK-3β mediates in the progesterone inhibition of estrogen induced cyclin D2 nuclear localization and cell proliferation in cyclin D1−/− mouse uterine epithelium, Wang Y, Feng H, Bi C, Zhu L, Pollard JW, Chen B, 2007

Brain Glioma Pathogenesis Treatment Glioma Brain Tumor Neuroscience Oncology Therapy Medical Research Neuro-Oncology Neuromuscular Diseases Rare Diseases Gene Therapy Genetics Muscle Disorders Neurology Biomedical Research Genetic Disorders Therapeutics Clinical Research

Bai Yun - Peking University

Hanyang Hu - Wuhan University

Shuping Peng - Central South University

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