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Zhang Wen
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
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Neural Circuits Brain Inhibitory Transmission Drug Dependence Schizophrenia Transgenic Mice Electrophysiology In Vivo Imaging Behavioral Studies Cerebral Cortex
Areas of Focus
  • Brain inhibitory transmission and neural circuits
  • Neural circuit mechanisms and treatments in drug dependence and schizophrenia
  • Development and function of inhibitory circuits in the cerebral cortex
Work Experience
  • 2010 – 2013 - The Jackson Laboratory, Postdoctoral Researcher
  • 2013 – 2016 - National Institutes of Health/National Institute of Drug Abuse, Postdoctoral Researcher
Academic Background & Achievements
  • 2008 - PhD in Neurobiology: University of Science and Technology of China
Publications
  • Protein kinase Mζ in medial prefrontal cortex mediates depressive-like behavior and antidepressant response, Yan W, Liu JF, Han Y, Zhang W, Luo YX, et al., 2017
  • BDNF rescues prefrontal dysfunction elicited by pyramidal neuron-specific DTNBP1 deletion in vivo, Zhang W, Daly KM, Liang B, Zhang L, Li X, et al., 2017
  • Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders, Zhang W, Zhang L, Liang B, Schroeder D, Zhang ZW, et al., 2016
  • Loss of MeCP2 from forebrain excitatory neurons leads to cortical hyperexcitation and seizures, Zhang W, Peterson M, Beyer B, Frankel WN, Zhang ZW, 2014
Awards
  • 2010 – 2013: The TJL Fellowship
  • 2015: The Fellows Award for Research Excellence, National Institutes of Health
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