Professor | Kailong Li | Asia Growth Partners

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Name	Kailong Li
Contact Information	kailongli@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Kailong Li

Contact Information

kailongli@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2015 - PhD in Pathology and Pathophysiology: Peking Union Medical College (Tsinghua University Medical Department) Published as first/co-first author in prestigious journals CPRIT Training Grant (2018, 2019)
Work Experience	2015-2021 - University of Texas Southwestern Medical Center, Postdoctoral Research in Jian Xu's lab Since June 2021 - Peking University, Associate Research Fellow
Awards	CPRIT Training Grant (2018, 2019): Grant for cancer research training Travel Award for Best Postdoc Poster, Cancer Biology Retreat (2019) Collaborator of the Year Award, CRI (2020)

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2015 - PhD in Pathology and Pathophysiology: Peking Union Medical College (Tsinghua University Medical Department)
Published as first/co-first author in prestigious journals
CPRIT Training Grant (2018, 2019)

Work Experience

2015-2021 - University of Texas Southwestern Medical Center, Postdoctoral Research in Jian Xu's lab
Since June 2021 - Peking University, Associate Research Fellow

Awards

CPRIT Training Grant (2018, 2019): Grant for cancer research training
Travel Award for Best Postdoc Poster, Cancer Biology Retreat (2019)
Collaborator of the Year Award, CRI (2020)

Areas of Focus	Role of non-coding regulatory sequence variations in cancer development and metastasis Mechanisms of chromatin three-dimensional structural changes in development and cancer progression Applications of epigenome editing systems in precision therapy for rare genetic diseases
Publications	Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19, Yao Y, Ye F, Li K, Xu P, Tan W, Feng Q, Rao S, 2021 Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies, Li K, Zhang Y, Liu X, Liu Y, Gu Z, Cao H, Dickerson KE, Chen M, Chen W, Shao Z, Ni M, Xu J, 2020 Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing, Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, Yu A, Kaphle P, Dickerson KE, Ni M, Xu J, 2020 Dissecting super-enhancer hierarchy based on chromatin interactions, Huang J, Li K, Cai W, Liu X, Zhang Y, Orkin SH, Xu J, Yuan GC, 2018 In Situ Capture of Chromatin Interactions by Biotinylated dCas9, Liu X, Zhang Y, Chen Y, Li M, Zhou F, Li K, Cao H, Ni M, Liu Y, Gu Z, Dickerson KE, Xie S, Hon GC, Xuan Z, Zhang MQ, Shao Z, Xu J, 2017 CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells, Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ, 2017

Areas of Focus

Role of non-coding regulatory sequence variations in cancer development and metastasis
Mechanisms of chromatin three-dimensional structural changes in development and cancer progression
Applications of epigenome editing systems in precision therapy for rare genetic diseases

Publications

Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19, Yao Y, Ye F, Li K, Xu P, Tan W, Feng Q, Rao S, 2021
Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies, Li K, Zhang Y, Liu X, Liu Y, Gu Z, Cao H, Dickerson KE, Chen M, Chen W, Shao Z, Ni M, Xu J, 2020
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing, Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, Yu A, Kaphle P, Dickerson KE, Ni M, Xu J, 2020
Dissecting super-enhancer hierarchy based on chromatin interactions, Huang J, Li K, Cai W, Liu X, Zhang Y, Orkin SH, Xu J, Yuan GC, 2018
In Situ Capture of Chromatin Interactions by Biotinylated dCas9, Liu X, Zhang Y, Chen Y, Li M, Zhou F, Li K, Cao H, Ni M, Liu Y, Gu Z, Dickerson KE, Xie S, Hon GC, Xuan Z, Zhang MQ, Shao Z, Xu J, 2017
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells, Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ, 2017

Non-Coding Regulatory Sequences Cancer Metastasis Chromatin Structure Development Cancer Progression Epigenome Editing Precision Therapy Genetic Diseases

Ying Zhao - Peking University

Jing Liang - Peking University

Zhang Yu - Peking University

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