Areas of Focus
- Protein post-translational modifications
- DNA damage repair
- Epigenetic regulation in cancer
Publications
- Acetylation of p62 regulates base excision repair through interaction with APE1, Wang H*
- Protein post-translational modifications in the regulation of cancer hallmarks, Wang H*, 2022
- Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis, Wang H*, 2017
- Downregulation of SIRT7 by 5-fluorouracil induces radiosensitivity in human colorectal cancer, Wang H*, 2017
- Quantitative proteome-based systematic identification of SIRT7 substrates, Wang H*, 2017
- Advances in cellular characterization of the sirtuin isoform, SIRT7, Wang H*, 2018
- The HDAC inhibitor depsipeptide transactivates the p53/p21 pathway by inducing DNA damage, Wang H*, 2012
- An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment, Wang H*, 2008
Awards
- 2009: Outstanding Young Scholar, Peking University Health Science Center
- 2011: Second Prize, Chinese Medical Science and Technology Award (Third Contributor)
- 2016: Second Prize, Beijing Natural Science and Technology (Eighth Contributor)