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Wenhua Yu
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Metabolism
Tumor
Cancer
Epigenetics
Histone
Deacetylation
Sirt7
Pancreatic Cancer
Breast Cancer
Pathophysiology
Areas of Focus
- Metabolism and tumor development
- Epigenetic mechanisms in cancer
- Histone deacetylation by SIRT7
- Pathophysiological significance in pancreatic and breast cancer
Work Experience
- 1997-2010 - Peking University, Department of Biochemistry and Molecular Biology - Assistant Teacher, Lecturer
- 2010-Present - Peking University, Department of Biochemistry and Molecular Biology - Associate Professor
Academic Background & Achievements
- 2001-2005, PhD: City University of Hong Kong, Biochemistry
- Hosted five National Natural Science Foundation projects
Publications
- PIM1-catalyzed CBX8 phosphorylation promotes the oncogene-induced senescence of human diploid fibroblast, Yu W, 2018
- Loss of circadian protein TIMELESS accelerates the progression of cellular senescence, Yu W, 2018
- PIM1 induces cellular senescence through phosphorylation of UHRF1 at Ser311, Yu W, 2017
- SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability, Yu W, 2016
- J Biol Chem, Yu W, 2010
- Biochim Biophys Acta, Yu W, 2006
- Arch. Biochem. Biophys., Yu W, 2005
