Professor | Zhan Jun | Asia Growth Partners

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Name

Zhan Jun

Contact Information

zhanjun@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2012: PhD in Basic Medicine, Peking University, Supervisor: Zhang Hongquan 2002-2005: Master's in Basic Medicine, Peking University, Supervisor: Tang Junmin 1993-1998: Bachelor in Clinical Medicine, Norman Bethune College of Medicine/Jilin University

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009-2012: PhD in Basic Medicine, Peking University, Supervisor: Zhang Hongquan
2002-2005: Master's in Basic Medicine, Peking University, Supervisor: Tang Junmin
1993-1998: Bachelor in Clinical Medicine, Norman Bethune College of Medicine/Jilin University

Areas of Focus	Molecular mechanisms of tumor occurrence, metastasis, and drug resistance Translational medical research
Publications	Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice, Zhan J, Zhang H, 2021 The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2, Zhan J, Zhang H, 2021 Kindlin-2 deficiency induces fatal intestinal obstruction in mice, Zhan J, Zhang H, 2020 Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1, Zhan J, Zhang H, 2019 C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Zhan J, Zhang H, 2019 HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients, Zhan J, Zhang H, 2019 HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression, Zhan J, Zhang H, 2018 Kindlin-2 Induced by TGF-β Signaling Promotes Pancreatic Ductal Adenocarcinoma Progression through Downregulation of Transcriptional Factor HOXB9, Zhan J, Zhang H, 2015 Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients, Zhan J, Zhang H, 2014 The spleen as a target in severe acute respiratory syndrome, Zhan J, Zhang H, 2006

Areas of Focus

Molecular mechanisms of tumor occurrence, metastasis, and drug resistance
Translational medical research

Publications

Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice, Zhan J*, Zhang H*, 2021
The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2, Zhan J*, Zhang H*, 2021
Kindlin-2 deficiency induces fatal intestinal obstruction in mice, Zhan J*, Zhang H*, 2020
Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1, Zhan J*, Zhang H*, 2019
C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Zhan J*, Zhang H*, 2019
HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients, Zhan J*, Zhang H*, 2019
HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression, Zhan J*, Zhang H*, 2018
Kindlin-2 Induced by TGF-β Signaling Promotes Pancreatic Ductal Adenocarcinoma Progression through Downregulation of Transcriptional Factor HOXB9, Zhan J*, Zhang H*, 2015
Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients, Zhan J*, Zhang H*, 2014
The spleen as a target in severe acute respiratory syndrome, Zhan J*, Zhang H*, 2006

Tumor Metastasis Drug Resistance Molecular Mechanisms Translational Research Cancer Chemotherapy Diagnostics Prognosis Kindlin-2

Xiaowei Zhang - Peking University

Ying Zhao - Peking University

Jing Liang - Peking University

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