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Zhan Jun
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Tumor
Metastasis
Drug Resistance
Molecular Mechanisms
Translational Research
Cancer
Chemotherapy
Diagnostics
Prognosis
Kindlin-2
Areas of Focus
- Molecular mechanisms of tumor occurrence, metastasis, and drug resistance
- Translational medical research
Academic Background & Achievements
- 2009-2012: PhD in Basic Medicine, Peking University, Supervisor: Zhang Hongquan
- 2002-2005: Master's in Basic Medicine, Peking University, Supervisor: Tang Junmin
- 1993-1998: Bachelor in Clinical Medicine, Norman Bethune College of Medicine/Jilin University
Publications
- Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice, Zhan J*, Zhang H*, 2021
- The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2, Zhan J*, Zhang H*, 2021
- Kindlin-2 deficiency induces fatal intestinal obstruction in mice, Zhan J*, Zhang H*, 2020
- Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1, Zhan J*, Zhang H*, 2019
- C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Zhan J*, Zhang H*, 2019
- HOXB13 networking with ABCG1/EZH2/Slug mediates metastasis and confers resistance to cisplatin in lung adenocarcinoma patients, Zhan J*, Zhang H*, 2019
- HOXB9 acetylation at K27 is responsible for its suppression of colon cancer progression, Zhan J*, Zhang H*, 2018
- Kindlin-2 Induced by TGF-β Signaling Promotes Pancreatic Ductal Adenocarcinoma Progression through Downregulation of Transcriptional Factor HOXB9, Zhan J*, Zhang H*, 2015
- Elevated HOXB9 expression promotes differentiation and predicts a favourable outcome in colon adenocarcinoma patients, Zhan J*, Zhang H*, 2014
- The spleen as a target in severe acute respiratory syndrome, Zhan J*, Zhang H*, 2006
