Professor | Pengyan Xia | Asia Growth Partners

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Name	Pengyan Xia
Contact Information	xiap@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Pengyan Xia

Contact Information

xiap@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	Joined Peking University School of Basic Medical Sciences, Department of Immunology in December 2018
Work Experience	2018 - Present - Peking University, Researcher and Doctoral Supervisor
Awards	2023: Beijing Outstanding Young Scientist Fund 2023: Fifth 'Peking University Young Scientist Award' 2023: Peking University Excellent Doctoral Dissertation Instructor 2023: Peking University Medical Department Teaching Excellence Award 2022: Peking University Medical Department Teaching Achievement Third Prize 2021: Peking University School of Basic Medical Sciences Excellent Teacher Award 2021: Beijing Natural Science Award Second Prize 2020: Fok Ying Tung Young Teacher Fund 2020: Peking University Green Leaf Biopharma Outstanding Young Scholar Award 2020: Peking University Boya Young Scholar 2019: Peking University School of Basic Medical Sciences Young Teacher Award Fund 2019: Peking University School of Basic Medical Sciences Sanquan Education Award 2018: Beijing Science and Technology Award First Prize

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Joined Peking University School of Basic Medical Sciences, Department of Immunology in December 2018

Work Experience

2018 - Present - Peking University, Researcher and Doctoral Supervisor

Awards

2023: Beijing Outstanding Young Scientist Fund
2023: Fifth 'Peking University Young Scientist Award'
2023: Peking University Excellent Doctoral Dissertation Instructor
2023: Peking University Medical Department Teaching Excellence Award
2022: Peking University Medical Department Teaching Achievement Third Prize
2021: Peking University School of Basic Medical Sciences Excellent Teacher Award
2021: Beijing Natural Science Award Second Prize
2020: Fok Ying Tung Young Teacher Fund
2020: Peking University Green Leaf Biopharma Outstanding Young Scholar Award
2020: Peking University Boya Young Scholar
2019: Peking University School of Basic Medical Sciences Young Teacher Award Fund
2019: Peking University School of Basic Medical Sciences Sanquan Education Award
2018: Beijing Science and Technology Award First Prize

Areas of Focus	Discovery of new pattern recognition receptors, Identification of new characteristic pathogenic molecules Exploration of the activation mechanisms of the NLRP3 inflammasome and its role in enteritis and dermatitis
Publications	Adipose triglyceride lipase suppresses non-canonical inflammasome by hydrolyzing LPS, Li W, Liu Q, Qian Y, Wang C, Kong C, Sun L, Sun L, Liu H, Zhang Y, Jiang D, Jiang C, Wang S, Xia P, 2024 The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome, Zhu F, Ma J, Li W, Liu Q, Qin X, Qian Y, Wang C, Zhang Y, Li Y, Jiang D, Wang S, Xia P, 2023 Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance, Zhang X, Yu D, Wu D, Gao X, Shao F, Zhao M, Wang J, Ma J, Wang W, Qin X, Chen Y, Xia P, Wang S, 2023 The neuropeptide CGRP enters the macrophage cytosol to suppress the NLRP3 inflammasome during pulmonary infection, Zhu F, Yu D, Qin X, Qian Y, Ma J, Li W, Liu Q, Wang C, Zhang Y, Li Y, Jiang D, Wang S, Xia P, 2023 AA467197 controls the hyperactivation of the NLRP3 inflammasome during infection, Liu Q, Li W, Qian Y, Wang C, Xia P, 2023 Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis, Zhao M, Shao F, Yu D, Zhang J, Liu Z, Ma J, Xia P, Wang S, 2022 SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage, Ma J, Zhu F, Zhao M, Shao F, Yu D, Ma J, Zhang X, Li W, Qian Y, Zhang Y, Jiang D, Wang S, Xia P*, 2021

Areas of Focus

Discovery of new pattern recognition receptors, Identification of new characteristic pathogenic molecules
Exploration of the activation mechanisms of the NLRP3 inflammasome and its role in enteritis and dermatitis

Publications

Adipose triglyceride lipase suppresses non-canonical inflammasome by hydrolyzing LPS, Li W, Liu Q, Qian Y, Wang C, Kong C, Sun L, Sun L, Liu H, Zhang Y, Jiang D, Jiang C, Wang S, Xia P*, 2024
The orphan receptor Nur77 binds cytoplasmic LPS to activate the non-canonical NLRP3 inflammasome, Zhu F, Ma J, Li W, Liu Q, Qin X, Qian Y, Wang C, Zhang Y, Li Y, Jiang D, Wang S*, Xia P*, 2023
Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance, Zhang X, Yu D, Wu D, Gao X, Shao F, Zhao M, Wang J, Ma J, Wang W, Qin X, Chen Y*, Xia P*, Wang S*, 2023
The neuropeptide CGRP enters the macrophage cytosol to suppress the NLRP3 inflammasome during pulmonary infection, Zhu F, Yu D, Qin X, Qian Y, Ma J, Li W, Liu Q, Wang C, Zhang Y, Li Y, Jiang D, Wang S*, Xia P*, 2023
AA467197 controls the hyperactivation of the NLRP3 inflammasome during infection, Liu Q, Li W, Qian Y, Wang C, Xia P*, 2023
Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis, Zhao M, Shao F, Yu D, Zhang J, Liu Z, Ma J, Xia P*, Wang S*, 2022
SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage, Ma J, Zhu F, Zhao M, Shao F, Yu D, Ma J, Zhang X, Li W, Qian Y, Zhang Y, Jiang D, Wang S*, Xia P*, 2021

Pattern Recognition Receptors Pathogenic Molecules Nlrp3 Inflammasome Activation Mechanisms Enteritis Dermatitis Immune Response Molecular Mechanisms Inflammation Pathogen Infection

Fu Yi - Peking University

Jun Zhang - Peking University

Wei Hou - Wuhan University

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