Professor | Jiadong Wang | Asia Growth Partners

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Name	Jiadong Wang
Language ability	Chinese, English
Province	Beijing

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Name

Jiadong Wang

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	Doctoral Supervisor Hosted National Outstanding Youth Science Fund and other projects Received the Excellent Young Scholar Award from the Chinese Society of Toxicology
Work Experience	Current - Peking University, Vice Director of Medical Department, Head of Radiology Department
Awards	2013: Best Paper at the 4th International Symposium on DNA Damage Response & Human Disease 2015: Outstanding Young Scholar in Green Leaf Biomedicine at Peking University 2014: Top Ten Excellent SCI Papers at Peking University Medical Department 2018: Excellent Teaching Award at Peking University Medical Department 2022: Outstanding Graduate Student Advisor at Peking University Medical Department

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Doctoral Supervisor
Hosted National Outstanding Youth Science Fund and other projects
Received the Excellent Young Scholar Award from the Chinese Society of Toxicology

Work Experience

Current - Peking University, Vice Director of Medical Department, Head of Radiology Department

Awards

2013: Best Paper at the 4th International Symposium on DNA Damage Response & Human Disease
2015: Outstanding Young Scholar in Green Leaf Biomedicine at Peking University
2014: Top Ten Excellent SCI Papers at Peking University Medical Department
2018: Excellent Teaching Award at Peking University Medical Department
2022: Outstanding Graduate Student Advisor at Peking University Medical Department

Areas of Focus	Tumor genesis mechanisms Tumor radiotherapy and chemotherapy resistance Synthetic therapy combining tumor radiotherapy and immunotherapy Genetic screening using CRISPR libraries, model organisms, and clinical models
Publications	KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression, Zhou XA, Zhou J, Zhao L, Yu G, Zhan J, Shi C, Yuan R, Wang Y, Chen C, Zhang W, Xu D, Ye Y, Wang W, Shen Z, Wang W, Wang J, 2020 C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou X, Li S, Li S, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu W, Xu X, Wang J, 2019 Acetylation of 53BP1 Dictates the DNA Double Strand Break Repair Pathway, Guo X, Bai Y, Zhao M, Zhou M, Shen Q, Caihong Yun, Zhang H, Zhu WG, Wang J, 2018 PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair, Zhao M, Geng R, Guo X, Yuan R, Zhou X, Zhong Y, Huo Y, Zhou M, Shen Q, Li Y, Zhu W, Wang J, 2017 Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA, Xu Z, Li X, Li H, Nie C, Liu W, Li S, Liu Z, Wang W, Wang J, 2020 Apatinib enhances antitumour activity of EGFR-TKIs in non-small cell lung cancer with EGFR-TKI resistance, Li F, Zhu T, Cao B, Wang J, Liang L, 2017 Artemis to dictate DNA repair pathway choice, Wang J#, Aroumougame A, Lobrich M, Li Y, Chen D, Chen J, Gong Z, 2014 TopBP1 controls BLM protein level to maintain genome stability, Wang J#, Chen J, Gong Z, 2013

Areas of Focus

Tumor genesis mechanisms
Tumor radiotherapy and chemotherapy resistance
Synthetic therapy combining tumor radiotherapy and immunotherapy
Genetic screening using CRISPR libraries, model organisms, and clinical models

Publications

KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression, Zhou XA, Zhou J, Zhao L, Yu G, Zhan J, Shi C, Yuan R, Wang Y, Chen C, Zhang W, Xu D, Ye Y, Wang W, Shen Z*, Wang W*, Wang J*, 2020
C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou X, Li S, Li S, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu W, Xu X, Wang J*, 2019
Acetylation of 53BP1 Dictates the DNA Double Strand Break Repair Pathway, Guo X, Bai Y, Zhao M, Zhou M, Shen Q, Caihong Yun, Zhang H, Zhu WG, Wang J*, 2018
PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair, Zhao M, Geng R, Guo X, Yuan R, Zhou X, Zhong Y, Huo Y, Zhou M, Shen Q, Li Y, Zhu W, Wang J*, 2017
Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA, Xu Z, Li X, Li H, Nie C, Liu W, Li S, Liu Z, Wang W*, Wang J*, 2020
Apatinib enhances antitumour activity of EGFR-TKIs in non-small cell lung cancer with EGFR-TKI resistance, Li F, Zhu T, Cao B, Wang J*, Liang L*, 2017
Artemis to dictate DNA repair pathway choice, Wang J#, Aroumougame A, Lobrich M, Li Y, Chen D, Chen J*, Gong Z*, 2014
TopBP1 controls BLM protein level to maintain genome stability, Wang J#, Chen J*, Gong Z*, 2013

Tumor Genesis Mechanisms Radiotherapy Chemotherapy Resistance Immunotherapy Crispr Genetic Screening

Zhan Jun - Peking University

Jiawen Feng - Peking University

Mao Yingqi Liang - Fudan University

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