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Jiadong Wang
Basic Medical Sciences
Peking University
Beijing
Language: Chinese, English
Tumor
Genesis
Mechanisms
Radiotherapy
Chemotherapy
Resistance
Immunotherapy
Crispr
Genetic
Screening
Areas of Focus
- Tumor genesis mechanisms
- Tumor radiotherapy and chemotherapy resistance
- Synthetic therapy combining tumor radiotherapy and immunotherapy
- Genetic screening using CRISPR libraries, model organisms, and clinical models
Work Experience
- Current - Peking University, Vice Director of Medical Department, Head of Radiology Department
Academic Background & Achievements
- Doctoral Supervisor
- Hosted National Outstanding Youth Science Fund and other projects
- Received the Excellent Young Scholar Award from the Chinese Society of Toxicology
Publications
- KLHL22 maintains PD-1 homeostasis and prevents excessive T cell suppression, Zhou XA, Zhou J, Zhao L, Yu G, Zhan J, Shi C, Yuan R, Wang Y, Chen C, Zhang W, Xu D, Ye Y, Wang W, Shen Z*, Wang W*, Wang J*, 2020
- C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex, Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou X, Li S, Li S, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu W, Xu X, Wang J*, 2019
- Acetylation of 53BP1 Dictates the DNA Double Strand Break Repair Pathway, Guo X, Bai Y, Zhao M, Zhou M, Shen Q, Caihong Yun, Zhang H, Zhu WG, Wang J*, 2018
- PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair, Zhao M, Geng R, Guo X, Yuan R, Zhou X, Zhong Y, Huo Y, Zhou M, Shen Q, Li Y, Zhu W, Wang J*, 2017
- Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA, Xu Z, Li X, Li H, Nie C, Liu W, Li S, Liu Z, Wang W*, Wang J*, 2020
- Apatinib enhances antitumour activity of EGFR-TKIs in non-small cell lung cancer with EGFR-TKI resistance, Li F, Zhu T, Cao B, Wang J*, Liang L*, 2017
- Artemis to dictate DNA repair pathway choice, Wang J#, Aroumougame A, Lobrich M, Li Y, Chen D, Chen J*, Gong Z*, 2014
- TopBP1 controls BLM protein level to maintain genome stability, Wang J#, Chen J*, Gong Z*, 2013
Awards
- 2013: Best Paper at the 4th International Symposium on DNA Damage Response & Human Disease
- 2015: Outstanding Young Scholar in Green Leaf Biomedicine at Peking University
- 2014: Top Ten Excellent SCI Papers at Peking University Medical Department
- 2018: Excellent Teaching Award at Peking University Medical Department
- 2022: Outstanding Graduate Student Advisor at Peking University Medical Department
