Professor | Weibin Wang | Asia Growth Partners

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Name	Weibin Wang
Contact Information	weibinwang@bjmu.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Weibin Wang

Contact Information

weibinwang@bjmu.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2004-2008: B.S., Capital Medical University, Department of Medical Experiment 2008-2011: M.S., Peking University Health Science Center, Department of Biochemistry and Molecular Biology 2011-2014: Ph.D., Peking University Health Science Center, Department of Biochemistry and Molecular Biology 2014-2019: Postdoc, Yale University, Department of Molecular Biophysics and Biochemistry
Work Experience	2019-Present: Assistant Professor, Peking University Health Science Center, Department of Radiation Medicine
Awards	2019: Start-up Research Grant for Newly Introduced Talents 2020: Grant from the National Natural Science Foundation of China 2022: Grant from the National Natural Science Foundation of China

University/Lab Affiliation and Title

Peking University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2004-2008: B.S., Capital Medical University, Department of Medical Experiment
2008-2011: M.S., Peking University Health Science Center, Department of Biochemistry and Molecular Biology
2011-2014: Ph.D., Peking University Health Science Center, Department of Biochemistry and Molecular Biology
2014-2019: Postdoc, Yale University, Department of Molecular Biophysics and Biochemistry

Work Experience

2019-Present: Assistant Professor, Peking University Health Science Center, Department of Radiation Medicine

Awards

2019: Start-up Research Grant for Newly Introduced Talents
2020: Grant from the National Natural Science Foundation of China
2022: Grant from the National Natural Science Foundation of China

Areas of Focus	DNA damage repair and its connections to tumors
Publications	Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin, Zhang T, Yang H, Zhou Z, Bai Y, Wang J, Wang W, 2022 Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles, Wang W, Daley JM, Kwon Y, Krasner DS, Sung P, 2017 C1QBP promotes homologous recombination by stabilizing MRE11 and controlling the assembly and activation of MRE11/RAD50/NBS1 complex, Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou XA, Li S, Li X, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu WG, Xu X, Wang J, 2019 The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression, Wang W, Pan K, Chen Y, Huang C, Zhang X, 2012 Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA, Xu Z, Li X, Li H, Nie C, Liu W, Li S, Liu Z, Wang W, Wang J, 2020 Transcriptional factor HBP1 targets p16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Li H, Wang W, Liu X, Paulson KE, Yee AS, Zhang X, 2010 A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection, Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P, 2018 PIASxalpha ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase, Wang W, Chen Y, Wang S, Hu N, Cao Z, Wang W, Tong T, Zhang X, 2014

Areas of Focus

DNA damage repair and its connections to tumors

Publications

Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin, Zhang T, Yang H, Zhou Z, Bai Y, Wang J, Wang W, 2022
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles, Wang W, Daley JM, Kwon Y, Krasner DS, Sung P, 2017
C1QBP promotes homologous recombination by stabilizing MRE11 and controlling the assembly and activation of MRE11/RAD50/NBS1 complex, Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou XA, Li S, Li X, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu WG, Xu X, Wang J, 2019
The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression, Wang W, Pan K, Chen Y, Huang C, Zhang X, 2012
Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA, Xu Z, Li X, Li H, Nie C, Liu W, Li S, Liu Z, Wang W, Wang J, 2020
Transcriptional factor HBP1 targets p16INK4A, upregulating its expression and consequently is involved in Ras-induced premature senescence, Li H, Wang W, Liu X, Paulson KE, Yee AS, Zhang X, 2010
A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1-Dna2 in long-range DNA end resection, Wang W, Daley JM, Kwon Y, Xue X, Krasner DS, Miller AS, Nguyen KA, Williamson EA, Shim EY, Lee SE, Hromas R, Sung P, 2018
PIASxalpha ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase, Wang W, Chen Y, Wang S, Hu N, Cao Z, Wang W, Tong T, Zhang X, 2014

Dna Repair Tumorigenesis Biochemistry Molecular Biology Cell Biology Animal Models Genome Stability Cancer Homologous Recombination Transcription-Replication Conflict

Huanran Tan - Peking University

Zhang Peng - Wuhan University

Yihao Tian - Wuhan University

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