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Yin Yuxin
yinyuxin@bjmu.edu.cn
English, Chinese
Beijing
Peking University
Basic Medical Sciences
  • 1997 - PhD in Molecular Biology and Genetics from University of North Carolina, USA
  • Postdoctoral research at Princeton University
  • Published over 160 SCI papers
  • 1999 - Present: Professor at Columbia University, USA
  • 2008 - Present: Shu Fan Chair Professor at Peking University
  • 2015 - Present: Lin Songnian Foundation Chair Professor at Peking University
  • 2017: Second Prize of the Chinese Medical Science and Technology Award
Role of tumor suppressor genes in cell cycle regulation, apoptosis, genomic stability, and cellular metabolism
Mechanisms of tumor immunity and immunotherapy
Metabolomics studies and early diagnosis of tumors
Mechanisms of brain cognition and memory
  • PAC1 phosphatase is a transcription target of p53 in signaling apoptosis and growth suppression, Yin, Y.*, Liu, Y. X., Jin, Y. J., Hall, E. J., and Barrett, J. C., 2003
  • Essential role for nuclear PTEN in maintaining chromosomal integrity, Shen, W. H., Balajee, A. B., Wang, J., Wu, H., Eng, C., Pandolfi, P. P., and Yin, Y.*, 2007
  • PTENα is a PTEN isoform Translated through Alternative Initiation and Regulates Mitochondrial Function, Liang, H., He, S., Yang, J., Jia, X., Wang, P., Chen, X., Zhang, Z., Zou, X., McNutt, M.A., Shen, W.H.,* and Yin, Y.*, 2014
  • The phosphatase DUSP2 controls the activity of the transcription activator STAT3 and regulates TH17 differentiation, Lu, D., Liu, L., Ji, X., Gao, Y., Chen, X., Liu, Y., Liu, Y., Zhao, X., Li, Y., Li, Y., Jin, Y., Zhang, Y., McNutt, M.A., Zhang, Y., and Yin, Y.*, 2015
  • The phosphatase pac1 acts as a t cell suppressor and attenuates host antitumor immunity, Lu, D., Liu, L., Sun, Y., Song, J., Yin, Q., Zhang, G., Qi, F., Hu, Z., Yang, Z., Zhou, Z., Hu, Y., Zhang, L., Ji, J., Zhao, X., Jin, Y., McNutt, M. A., Yin, Y*., 2020
  • Systematic analyses of early-stage lung cancer by scRNA-seq and lipidomic reveal aberrant lipid metabolism as detection biomarkers, Wang, G., Qiu, M., Xing, X., Zhou, J., Yao, H., Li, M., Yin, R., Hou, Y., Li, Y., Pan, S., Huang, Y., Yang, F., Bai, F., Nie, H., Di, S., Guo, L., Meng, Z., Wang, J., Yin, Y*., 2022
Tumor Suppressor Genes Cell Cycle Apoptosis Genomic Stability Cellular Metabolism Tumor Immunity Immunotherapy Metabolomics Early Diagnosis Brain Cognition

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