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Yixian Cui
Immunology and Metabolion
Wuhan University
Hubei
Language: Chinese, English
Autophagy
Disease
Cellular Homeostasis
Metabolic Disorders
Cancer
Neurodegenerative Diseases
Endoplasmic Reticulum
Genetic Screening
Yeast
Molecular Mechanisms
Areas of Focus
- Selective autophagy and disease occurrence
Work Experience
- 2013-2015 - Tsinghua University - Postdoctoral Researcher
- 2015-2019 - University of California, San Diego - Postdoctoral Researcher and Assistant Project Scientist
- 2019-present - Wuhan University Medical Research Institute/Center for Advanced Studies in Immunology and Metabolism - Professor and Doctoral Supervisor
- Special Appointment as Professor at Zhongnan Hospital of Wuhan University
Academic Background & Achievements
- 2003-2007 Bachelor: Hunan University, School of Life Sciences and Technology
- 2007-2013 PhD: Tsinghua University, School of Life Sciences
Publications
- A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation, Yixian Cui, Smriti Parashar, Muhammad Zahoor, Patrick G. Needham, Muriel Mari, Ming Zhu, Shuliang Chen, Hsuan-Chung Ho, Fulvio Reggiori, Hesso Farhan, Jeffrey L. Brodsky, and Susan Ferro-Novick, 2019
- UVRAG cooperates with cargo receptors to assemble the ER-phagy site, Xuehong Qian, Lingang He, Jiejie Yang, Jiajia Sun, Xueying Peng, Yuting Zhang, Yizhou Mao, Ying Zhang and Yixian Cui, 2023
- Upregulation of neuronal ER-phagy improves organismal fitness and alleviates APP toxicity, Wenqing Mou, Yinglu Tang, Yunpeng Huang, Zhihao Wu, Yixian Cui, 2024
- UVRAG: orchestrating the initiation of reticulophagy, Xuehong Qian, Jiajia Sun and Yixian Cui, 2023
- Advances in ER-phagy and its diseases relevance, Lingang He, Xuehong Qian, Yixian Cui, 2021
- A new role for a COPII cargo adaptor in autophagy, Yixian Cui, Smriti Parashar, and Susan Ferro-Novick, 2019
- ER-phagy requires Lnp1, a protein that stabilizes rearrangements of the ER network, Shuliang Chen, Muriel Mari, Smriti Parashar, Dongmei Liu, Yixian Cui, Fulvio Reggiori, Peter J. Novick, Susan Ferro-Novick, 2018
- Vps13 is required for the packaging of the ER into autophagosomes during ER-phagy, Shuliang Chen, Muriel Mari, Smriti Parashar, Dongmei Liu, Yixian Cui, Fulvio Reggiori, Peter J. Novick, Susan Ferro-Novick, 2020
- A novel Drosophila mitochondrial carrier protein acts as a Mg2+ exporter in fine-tuning mitochondrial Mg2+ homeostasis, Yixian Cui, Shanke Zhao, Xudong Wang, Bing Zhou, 2016
- A novel mitochondrial carrier protein Mme1 acts as a yeast mitochondrial magnesium exporter, Yixian Cui, Shanke Zhao, Juan Wang, Xudong Wang, Bingquan Gao, Qiangwang Fan, Fei Sun, Bing Zhou, 2015
- Mitochondrial release of the NADH dehydrogenase Ndi1 induces apoptosis in yeast, Yixian Cui, Shanke Zhao, Zhihao Wu, Pinghua Dai, Bing Zhou, 2012
Awards
- Overseas High-level Talent Plan A (2021-2023): Lead
- National Key R&D Program of the Ministry of Science and Technology (2021-2025): Team Leader
- National Key R&D Program of the Ministry of Science and Technology (2021-2024): Core Member
- National Natural Science Foundation of China (2021-2024): Lead
- National Natural Science Foundation of China (2024-2027): Lead
- National Natural Science Foundation of China Young Scientist Fund (2014-2016): Lead
- Wuhan University 'Double First-Class' Initiative Talent Start-up Fund (2020-2022): Lead
