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Ying Zhang
Immunology and Metabolion
Wuhan University
Hubei
Language: English, Chinese
Gene Therapy
Stem Cells
Crispr
Cancer Treatment
Immune Cells
Cell Gene Editing
Precise Therapy
Hematopoietic
Design
Construction
Areas of Focus
- Gene therapy using hematopoietic stem cells
- Cancer treatment through immune cell enhancement using CRISPR technology
- Design and construction of cell gene editing tools for precise therapy
Work Experience
- 2012-2015 - Harvard Medical School - Postdoctoral Researcher
- 2015-2018 - CRISPR Therapeutics - Senior Researcher
- 2018- - Wuhan University Medical Research Institute - Professor
Academic Background & Achievements
- 2002-2006 Bachelor: Nankai University, School of Life Sciences
- 2006-2012 PhD: University of Colorado Anschutz Medical Campus
- Outstanding Doctoral Dissertation Award 2012: University of Colorado Anschutz Medical Campus
Publications
- Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable offtarget mutations in human HSCs, Ying Zhang et al., 2023
- Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS-STING pathway, Ying Zhang et al., 2023
- Efficient non-viral delivery of macromolecules in human primary hematopoietic stem cells and lymphocytes, Ying Zhang et al., 2023
- Cas12a-based one-pot SNP detection with high accuracy, Ying Zhang et al., 2023
- Current advances of CRISPR-Cas technology in cell therapy, Ying Zhang et al., 2022
- DNA topology regulates PAM-Cas9 interaction and DNA unwinding to enable near PAMless cleavage by thermophilic Cas9, Ying Zhang et al., 2022
- Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a, Ying Zhang et al., 2022
Awards
- 2019 Hubei Province Science and Technology Innovation bairen Plan
- 2012 Outstanding Doctoral Dissertation Award: University of Colorado Anschutz Medical Campus
- 2009 24th Outstanding Research Award: University of Colorado Anschutz Medical Campus
