Professor | Tan Yueqiu | Asia Growth Partners

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Name	Tan Yueqiu
Contact Information	tanyueqiu@csu.edu.cn
Language ability	Chinese, English
Province	Hunan

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Name

Tan Yueqiu

Contact Information

tanyueqiu@csu.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1991-1997: Bachelor of Biology, Hunan Normal University 1997-2002: Master and PhD in Medical Genetics, Hunan Medical University and Central South University Key project leader in national key R&D programs and fundamental research programs Recipient of the National Science and Technology Progress Second Prize Recipient of the First Prize of Scientific and Technological Progress by the Ministry of Education
Work Experience	1991.7-1993.2: Intern Researcher, National Key Laboratory of Medical Genetics, Hunan Medical University 2002.9-present: Associate Researcher (2002), Researcher (2007), Reproductive and Stem Cell Engineering Institute, Central South University
Awards	2006: Hunan Province Youth Key Teacher 2013: Hunan Province Medical Science Key Talent 2019: Leader of Hunan Province Medical Genetics Discipline

University/Lab Affiliation and Title

Central South University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1991-1997: Bachelor of Biology, Hunan Normal University
1997-2002: Master and PhD in Medical Genetics, Hunan Medical University and Central South University
Key project leader in national key R&D programs and fundamental research programs
Recipient of the National Science and Technology Progress Second Prize
Recipient of the First Prize of Scientific and Technological Progress by the Ministry of Education

Work Experience

1991.7-1993.2: Intern Researcher, National Key Laboratory of Medical Genetics, Hunan Medical University
2002.9-present: Associate Researcher (2002), Researcher (2007), Reproductive and Stem Cell Engineering Institute, Central South University

Awards

2006: Hunan Province Youth Key Teacher
2013: Hunan Province Medical Science Key Talent
2019: Leader of Hunan Province Medical Genetics Discipline

Areas of Focus	Medical Genetics: New gene screening and functional analysis for gametogenesis disorders (azoospermia, oligospermia, and premature ovarian failure) Clinical Genetics: Diagnosis of genetic diseases, prenatal diagnosis, and pre-implantation genetic testing
Publications	Defective piRNA Processing and Azoospermia, Wang X, Tan YQ, Liu MF, 2022 Loss-of-function variants in human C12orf40 cause male infertility by blocking meiotic progression, Tu C, Wen J, Wang W, Zhu Q, Chen Y, Cheng J, Li Z, Meng L, Li Y, He W, Tan C, Xie C, Fu S, Du J, Lu G, Lin G, Gou LT, Tan YQ, 2023 DRC3 is an assembly adapter of the nexin-dynein regulatory complex functional components during spermatogenesis in humans and mice, Zhou S, Yuan S, Zhang J, Meng L, Zhang X, Liu S, Lu G, Lin G, Liu M, Tan YQ, 2023 Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly, Lu S, Gu Y, Wu Y, Yang S, Li C, Meng L, Yuan W, Jiang T, Zhang X, Li Y, Wang C, Liu M, Ye L, Guo X, Shen H, Yang X, Tan Y, Hu Z, 2021 Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice, Tu C, Cong J, Zhang Q, He X, Zheng R, Yang X, Gao Y, Wu H, Lv M, Gu Y, Lu S, Liu C, Tian S, Meng L, Wang W, Tan C, Nie H, Li D, Zhang H, Gong F, Hu L, Lu G, Xu W, Lin G, Zhang F, Cao Y, Tan YQ, 2021 TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation, Tu C, Li H, Liu X, Wang Y, Li W, Meng L, Wang W, Li Y, Li D, Du J, Lu G, Lin G, Tan YQ, 2021 Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility, Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F, 2021 Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice, Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ, 2022 Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia, Xie C, Wang W, Tu C, Meng L, Lu G, Lin G, Lu LY, Tan YQ, 2022 Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models, Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao C, Li C, Kherraf ZE, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, Liu Q, Tang S, Wang J, Saiyin H, Zhao L, Yang L, Meng L, Chen B, Tang D, Zhou Y, Wu H, Lv M, Tan C, Lin G, Kong Q, Shi H, Su Z, Li Z, Yao YG, Jin L, Zheng P, Ray PF, Tan YQ, Cao Y, Zhang F, 2023 Loss-of-function mutations TDRD7 lead to a rare novel syndrome combining congenital cataract and non-obstructive azoospermia in humans, Tan YQ, Tu CF, Meng LL, Yuan SM, Sjaarda C, Luo AX, Du J, Li W, Gong F, Zhong CG, Deng HX, Lu GX, Liang P, Lin G, 2019 Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermia, Hu T, Meng L, Tan C, Luo C, He WB, Tu C, Zhang H, Du J, Nie H, Lu GX, Lin G, Tan YQ, 2023 Biallelic variants in KCTD19 associated with male factor infertility and oligoasthenoteratozoospermia, Wang W, Su L, Meng L, He J, Tan C, Yi D, Cheng D, Zhang H, Lu G, Du J, Lin G, Zhang Q, Tu C, Tan YQ, 2023 A homozygous RPL10L missense mutation associated with male factor infertility and severe oligozoospermia, Tu C, Meng L, Nie H, Yuan S, Wang W, Du J, Lu G, Lin G, Tan YQ, 2020 Homozygous variants in SYCP2L cause premature ovarian insufficiency, He WB, Tan C, Zhang YX, Meng LL, Gong F, Lu GX, Lin G, Du J, Tan YQ, 2021 CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis, Wang W, Tian S, Nie H, Tu C, Liu C, Li Y, Li D, Yang X, Meng L, Hu T, Zhang Q, Du J, Fan L, Lu G, Lin G, Zhang F, Tan YQ, 2021

Areas of Focus

Medical Genetics: New gene screening and functional analysis for gametogenesis disorders (azoospermia, oligospermia, and premature ovarian failure)
Clinical Genetics: Diagnosis of genetic diseases, prenatal diagnosis, and pre-implantation genetic testing

Publications

Defective piRNA Processing and Azoospermia, Wang X, Tan YQ, Liu MF, 2022
Loss-of-function variants in human C12orf40 cause male infertility by blocking meiotic progression, Tu C, Wen J, Wang W, Zhu Q, Chen Y, Cheng J, Li Z, Meng L, Li Y, He W, Tan C, Xie C, Fu S, Du J, Lu G, Lin G, Gou LT, Tan YQ, 2023
DRC3 is an assembly adapter of the nexin-dynein regulatory complex functional components during spermatogenesis in humans and mice, Zhou S, Yuan S, Zhang J, Meng L, Zhang X, Liu S, Lu G, Lin G, Liu M, Tan YQ, 2023
Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly, Lu S, Gu Y, Wu Y, Yang S, Li C, Meng L, Yuan W, Jiang T, Zhang X, Li Y, Wang C, Liu M, Ye L, Guo X, Shen H, Yang X, Tan Y, Hu Z, 2021
Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice, Tu C, Cong J, Zhang Q, He X, Zheng R, Yang X, Gao Y, Wu H, Lv M, Gu Y, Lu S, Liu C, Tian S, Meng L, Wang W, Tan C, Nie H, Li D, Zhang H, Gong F, Hu L, Lu G, Xu W, Lin G, Zhang F, Cao Y, Tan YQ, 2021
TDRD7 participates in lens development and spermiogenesis by mediating autophagosome maturation, Tu C, Li H, Liu X, Wang Y, Li W, Meng L, Wang W, Li Y, Li D, Du J, Lu G, Lin G, Tan YQ, 2021
Deleterious variants in X-linked CFAP47 induce asthenoteratozoospermia and primary male infertility, Liu C, Tu C, Wang L, Wu H, Houston BJ, Mastrorosa FK, Zhang W, Shen Y, Wang J, Tian S, Meng L, Cong J, Yang S, Jiang Y, Tang S, Zeng Y, Lv M, Lin G, Li J, Saiyin H, He X, Jin L, Touré A, Ray PF, Veltman JA, Shi Q, O'Bryan MK, Cao Y, Tan YQ, Zhang F, 2021
Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice, Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ, 2022
Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia, Xie C, Wang W, Tu C, Meng L, Lu G, Lin G, Lu LY, Tan YQ, 2022
Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models, Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao C, Li C, Kherraf ZE, Ye M, Zhou Z, Ma Y, Gao Y, Li Y, Liu Q, Tang S, Wang J, Saiyin H, Zhao L, Yang L, Meng L, Chen B, Tang D, Zhou Y, Wu H, Lv M, Tan C, Lin G, Kong Q, Shi H, Su Z, Li Z, Yao YG, Jin L, Zheng P, Ray PF, Tan YQ, Cao Y, Zhang F, 2023
Loss-of-function mutations TDRD7 lead to a rare novel syndrome combining congenital cataract and non-obstructive azoospermia in humans, Tan YQ, Tu CF, Meng LL, Yuan SM, Sjaarda C, Luo AX, Du J, Li W, Gong F, Zhong CG, Deng HX, Lu GX, Liang P, Lin G, 2019
Biallelic CFAP61 variants cause male infertility in humans and mice with severe oligoasthenoteratozoospermia, Hu T, Meng L, Tan C, Luo C, He WB, Tu C, Zhang H, Du J, Nie H, Lu GX, Lin G, Tan YQ, 2023
Biallelic variants in KCTD19 associated with male factor infertility and oligoasthenoteratozoospermia, Wang W, Su L, Meng L, He J, Tan C, Yi D, Cheng D, Zhang H, Lu G, Du J, Lin G, Zhang Q, Tu C, Tan YQ, 2023
A homozygous RPL10L missense mutation associated with male factor infertility and severe oligozoospermia, Tu C, Meng L, Nie H, Yuan S, Wang W, Du J, Lu G, Lin G, Tan YQ, 2020
Homozygous variants in SYCP2L cause premature ovarian insufficiency, He WB, Tan C, Zhang YX, Meng LL, Gong F, Lu GX, Lin G, Du J, Tan YQ, 2021
CFAP65 is required in the acrosome biogenesis and mitochondrial sheath assembly during spermiogenesis, Wang W, Tian S, Nie H, Tu C, Liu C, Li Y, Li D, Yang X, Meng L, Hu T, Zhang Q, Du J, Fan L, Lu G, Lin G, Zhang F, Tan YQ, 2021

Genetics Gametogenesis Azoospermia Oligospermia Ovarian Failure Gene Screening Functional Analysis Genetic Diseases Prenatal Diagnosis Genetic Testing

Jiahao Sha - Nanjing Medical University

Duan Ma - Fudan University

Jian Zhang - Southern Medical University

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