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Wanqiu Li
Medical School
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Cryo-Em
Biochemistry
Molecular Biology
Cell Biology
Biomolecular Structures
Disease-Related
Drug Development
Therapeutic Strategies
Epigenetic Regulation
Molecular Mechanisms
Areas of Focus
- Study of disease-related biomolecular structures and functions using cryo-EM, biochemistry, molecular biology, and cell biology
Work Experience
- 2017.07-2019.09 - Southern University of Science and Technology, Department of Biology, Postdoctoral Researcher (Outstanding Postdoctoral)
- 2018.04-2018.07 - Peter Mac Cancer Research Center, Australia, Honorary Visiting Scholar
- 2019.10-2021.02 - Southern University of Science and Technology, Department of Biology, Senior Research Scholar
- 2021.03-present - Southern University of Science and Technology, School of Medicine, Assistant Professor
Academic Background & Achievements
- 2008-2012 Bachelor in Horticulture: China Agricultural University
- 2012-2017 PhD in Biophysics, Structural Biology: Tsinghua University
Publications
- Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases, Li, W., Tian, W., Yuan, G., Deng, P., Sengupta, D., Cheng, Z., Cao, Y., Ren, J., Qin, Y., Zhou, Y., Jia, Y., Gozani, O., Patel, D. J., Wang, Z., 2021
- Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase, Lin, F., Zhang, R., Shao, W., Lei, C., Ma, M., Zhang, Y., Wen, Z., Li, W., 2023
- Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release, Li, W., Wang, L., Wierbowski, B. M., Lu, M., Dong, F., Liu, W., Li, S., Wang, P., Salic, A., Gong, X., 2021
- Architecture of the mammalian mechanosensitive Piezo1 channel, Ge, J., Li, W., Zhao, Q., Li, N., Chen, M., Zhi, P., Li, R., Gao, N., Xiao, B., Yang, M., 2015
- Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation, Wang, W., Li, W., Ge, X., Yan, K., Mandava, C. S., Sanyal, S., Gao, N., 2020
- The Structural Basis for Sensing by the Piezo1 Protein, Li, W., Gao, N., Yang, M., 2017
- Nuclear export of circular RNA, Ngo, L. H., Bert, A. G., Dredge, B. K., Williams, T., Murphy, V., Li, W., Hamilton, W. B., Carey, K. T., Toubia, J., Pillman, K. A., Liu, D., Desogus, J., Chao, J. A., Deans, A. J., Goodall, G. J., Wickramasinghe, V. O., 2024
- Structure of the eukaryotic MCM complex at 3.8 A, Li, N., Zhai, Y., Zhang, Y., Li, W., Yang, M., Lei, J., Tye, B. K., Gao, N., 2015
Awards
- 2023 Shenzhen Science and Technology Award - Youth Science and Technology Award
- 2022 Shenzhen Excellent Youth
- 2021 Shenzhen High-level National Leading Talent
- 2017 Outstanding Postdoctoral at Southern University of Science and Technology
- 2016 Tsinghua University Structural Biology Innovation Center Outstanding PhD Student Scholarship
- 2015 Tsinghua-Amgen Scholars Forum Outstanding Poster Award
