Professor | Haocheng Lu | Asia Growth Partners

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Name	Haocheng Lu
Contact Information	luhc@sustech.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Haocheng Lu

Contact Information

luhc@sustech.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	2008-2014 Bachelor in Clinical Medicine: Peking University 2008-2014 Bachelor in Economics (Dual Degree): National Development Research Institute, Peking University 2014-2019 PhD in Physiology: University of Michigan
Work Experience	2019-2022 Postdoctoral Research Fellow, University of Michigan Medical School 2022-present Assistant Professor, Southern University of Science and Technology
Awards	2016-2018 Predoctoral fellowship: American Heart Association 2018 Young Investigator Award: Chinese American Academy of Cardiology, Chinese Society for Vascular Medicine

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

2008-2014 Bachelor in Clinical Medicine: Peking University
2008-2014 Bachelor in Economics (Dual Degree): National Development Research Institute, Peking University
2014-2019 PhD in Physiology: University of Michigan

Work Experience

2019-2022 Postdoctoral Research Fellow, University of Michigan Medical School
2022-present Assistant Professor, Southern University of Science and Technology

Awards

2016-2018 Predoctoral fellowship: American Heart Association
2018 Young Investigator Award: Chinese American Academy of Cardiology, Chinese Society for Vascular Medicine

Areas of Focus	Discovery of pathogenic genes for cardiovascular diseases based on GWAS and multi-omics data, combined with in vitro experiments and animal models Utilization of in vivo CRISPR screening to discover key regulatory genes involved in disease development by macrophages Exploration of the translational medical value of newly discovered pathogenic genes, development of new therapeutic targets
Publications	RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II, Wang Z, Lu H, Garcia-Barrio M, Guo Y, Zhang J, Chen YE, Chang L, 2022 Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms, Lu H, Du W, Ren L, Hamblin MH, Becker RC, Chen YE, Fan Y, 2021 Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2, Fan Y, Wolford BN, Lu H, Liang W, Sun J, Zhou W, Rom O, Mahajan A, Surakka I, Graham SE, Liu Z, Kim H, Ramdas S, Fritsche LG, Nielsen JB, Gabrielsen ME, Hveem K, Yang D, Song J, Garcia-Barrio MT, Zhang J, Liu W, Zhang K, Willer CJ, Chen YE, 2021 Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm, Roychowdhury T, Lu H*, Hornsby WE, Crone B, Wang GT, Guo DC, Sendamarai AK, Devineni P, Lin M, Zhou W, Graham SE, Wolford BN, Surakka I, Wang Z, Chang L, Zhang J, Mathis M, Brummett CM, Melendez TL, Shea MJ, Kim KM, Deeb GM, Patel HJ, Eliason J, Eagle KA, Yang B, Ganesh SK, Brumpton B, Åsvold BO, Skogholt AH, Hveem K, Pyarajan S, Klarin D, Tsao PS, Damrauer SM, Leal SM, Milewicz DM, Chen YE, Garcia-Barrio MT, Willer CJ, 2021 Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases, Lu H, Zhang J, Chen YE, Garcia-Barrio MT, 2021 Transcription factor EB regulates cardiovascular homeostasis, Lu H, Sun J, Hamblin MH, Chen YE, Fan Y, 2021 Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB, Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y, 2020 Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells, Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y, 2019 TFEB inhibits endothelial cell inflammation and reduces atherosclerosis, Lu H, Fan Y, Qiao C, Liang W, Hu W, Zhu T, Zhang J, Chen YE, 2017

Areas of Focus

Discovery of pathogenic genes for cardiovascular diseases based on GWAS and multi-omics data, combined with in vitro experiments and animal models
Utilization of in vivo CRISPR screening to discover key regulatory genes involved in disease development by macrophages
Exploration of the translational medical value of newly discovered pathogenic genes, development of new therapeutic targets

Publications

RNA sequencing reveals perivascular adipose tissue plasticity in response to angiotensin II, Wang Z*, Lu H*, Garcia-Barrio M, Guo Y, Zhang J, Chen YE, Chang L, 2022
Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms, Lu H, Du W, Ren L, Hamblin MH, Becker RC, Chen YE, Fan Y, 2021
Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2, Fan Y*, Wolford BN*, Lu H*, Liang W, Sun J, Zhou W, Rom O, Mahajan A, Surakka I, Graham SE, Liu Z, Kim H, Ramdas S, Fritsche LG, Nielsen JB, Gabrielsen ME, Hveem K, Yang D, Song J, Garcia-Barrio MT, Zhang J, Liu W, Zhang K, Willer CJ, Chen YE, 2021
Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm, Roychowdhury T*, Lu H*, Hornsby WE, Crone B, Wang GT, Guo DC, Sendamarai AK, Devineni P, Lin M, Zhou W, Graham SE, Wolford BN, Surakka I, Wang Z, Chang L, Zhang J, Mathis M, Brummett CM, Melendez TL, Shea MJ, Kim KM, Deeb GM, Patel HJ, Eliason J, Eagle KA, Yang B, Ganesh SK, Brumpton B, Åsvold BO, Skogholt AH, Hveem K, Pyarajan S, Klarin D, Tsao PS, Damrauer SM, Leal SM, Milewicz DM, Chen YE, Garcia-Barrio MT, Willer CJ, 2021
Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases, Lu H, Zhang J, Chen YE, Garcia-Barrio MT, 2021
Transcription factor EB regulates cardiovascular homeostasis, Lu H, Sun J, Hamblin MH, Chen YE, Fan Y, 2021
Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB, Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y, 2020
Novel gene regulatory networks identified in response to nitro-conjugated linoleic acid in human endothelial cells, Lu H, Sun J, Liang W, Zhang J, Rom O, Garcia-Barrio MT, Li S, Villacorta L, Schopfer FJ, Freeman BA, Chen YE, Fan Y, 2019
TFEB inhibits endothelial cell inflammation and reduces atherosclerosis, Lu H, Fan Y, Qiao C, Liang W, Hu W, Zhu T, Zhang J, Chen YE, 2017

Gwas Multi-Omics Cardiovascular Diseases In Vitro Experiments Animal Models Crispr Screening Macrophages Disease Development Translational Medicine Therapeutic Targets

Zhang Peng - Wuhan University

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