Areas of Focus
- In situ structural mechanisms of membrane remodeling
- Method development for cryo-electron microscopy
Work Experience
- 2023-Present - Southern University of Science and Technology - Assistant Professor
- 2019-2023 - Yale University - Postdoctoral Researcher (Dr. Pietro De Camilli's lab)
- 2018-2019 - National University of Singapore - Postdoctoral Researcher (Dr. Lu Gan's lab)
Academic Background & Achievements
- 2013-2018 PhD: National University of Singapore
- 2009-2013 Bachelor: Beijing Normal University
Publications
- In situ architecture of the lipid transport protein VPS13C at ER-lysosome membrane contacts, Cai, S., Wu, Y., Guillen-Samander, A., Hancock-Cerutti, W., Liu, J., and De Camilli, P., 2022
- Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ, Tan, Z.Y.*, Cai, S.*, Noble, A.J.*, Chen, J.K.*, Shi, J., and Gan, L., 2023
- The in-situ structures of mono-, di-, and trinucleosomes in human heterochromatin, Cai, S.*, Bock, D.*, Pilhofer, M., and Gan, L., 2018
- Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo, Cai, S., Chen, C., Tan, Z.Y., Huang, Y., Shi, J., and Gan, L., 2018
- Natural chromatin is heterogeneous and self-associates in vitro, Cai, S., Song, Y., Chen, C., Shi, J., and Gan, L., 2018
Awards
- 2020-2022: Parkinson's Foundation Postdoctoral Fellowship