Professor | Weiwei Shi | Asia Growth Partners

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Name	Weiwei Shi
Contact Information	shiww@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Weiwei Shi

Contact Information

shiww@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Life Sciences
Academic Background & Achievements	2014 - PhD in Science: University of Science and Technology of China Postdoctoral research at The Chinese University of Hong Kong (2014-2018)
Work Experience	2019 - Present: Associate Research Professor at Southern University of Science and Technology

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Life Sciences

Academic Background & Achievements

2014 - PhD in Science: University of Science and Technology of China
Postdoctoral research at The Chinese University of Hong Kong (2014-2018)

Work Experience

2019 - Present: Associate Research Professor at Southern University of Science and Technology

Areas of Focus	Pathogenic molecular mechanisms of novel drug target proteins Structure and function-based drug discovery and development
Publications	Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase, Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC, 2021 Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation, Shou JW, Cheung CK, Gao J, Shi WW, Shaw PC, 2019 Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein, Shi WW, Wong KB, Shaw PC, 2018 Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins, Shi WW, Mak AN, Wong KB, Shaw PC, 2016 Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2, Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC, 2016 Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins, Shi WW, Jiang YL, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H, Chen Y, Zhou CZ, 2014 Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC, Du Y, Shi WW, He YX, Yang YH, Zhou CZ, Chen Y, 2011

Areas of Focus

Pathogenic molecular mechanisms of novel drug target proteins
Structure and function-based drug discovery and development

Publications

Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase, Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC, 2021
Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation, Shou JW, Cheung CK, Gao J, Shi WW, Shaw PC, 2019
Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein, Shi WW, Wong KB, Shaw PC, 2018
Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins, Shi WW, Mak AN, Wong KB, Shaw PC, 2016
Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2, Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC, 2016
Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins, Shi WW, Jiang YL, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H, Chen Y, Zhou CZ, 2014
Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC, Du Y, Shi WW, He YX, Yang YH, Zhou CZ, Chen Y, 2011

Drug Targets Pathogenesis Molecular Mechanisms Protein Research Drug Discovery Drug Development Structural Biology Biochemistry Molecular Biology Pharmacology

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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