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Weiwei Shi
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Drug Targets
Pathogenesis
Molecular Mechanisms
Protein Research
Drug Discovery
Drug Development
Structural Biology
Biochemistry
Molecular Biology
Pharmacology
Areas of Focus
- Pathogenic molecular mechanisms of novel drug target proteins
- Structure and function-based drug discovery and development
Work Experience
- 2019 - Present: Associate Research Professor at Southern University of Science and Technology
Academic Background & Achievements
- 2014 - PhD in Science: University of Science and Technology of China
- Postdoctoral research at The Chinese University of Hong Kong (2014-2018)
Publications
- Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase, Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC, 2021
- Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation, Shou JW, Cheung CK, Gao J, Shi WW, Shaw PC, 2019
- Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein, Shi WW, Wong KB, Shaw PC, 2018
- Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins, Shi WW, Mak AN, Wong KB, Shaw PC, 2016
- Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2, Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC, 2016
- Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins, Shi WW, Jiang YL, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H, Chen Y, Zhou CZ, 2014
- Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC, Du Y, Shi WW, He YX, Yang YH, Zhou CZ, Chen Y, 2011
