Professor | 师伟伟 | 数字化转型顾问

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Name

师伟伟

Contact Information

shiww@sustech.edu.cn

Language ability

中文, 英语

Province

广东省

University/Lab Affiliation and Title	南方科技大学
Faculty	Life Sciences
Academic Background & Achievements	2014 - 理学博士学位: 中国科学技术大学香港中文大学博士后研究 (2014-2018)
Work Experience	2019 - 至今: 南方科技大学研究副教授

University/Lab Affiliation and Title

南方科技大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	新型药物靶点蛋白的致病分子机制研究基于结构与功能的新型药物发现和开发
Publications	Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase, Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC, 2021 Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation, Shou JW, Cheung CK, Gao J, Shi WW, Shaw PC, 2019 Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein, Shi WW, Wong KB, Shaw PC, 2018 Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins, Shi WW, Mak AN, Wong KB, Shaw PC, 2016 Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2, Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC, 2016 Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins, Shi WW, Jiang YL, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H, Chen Y, Zhou CZ, 2014 Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC, Du Y, Shi WW, He YX, Yang YH, Zhou CZ, Chen Y, 2011

Areas of Focus

新型药物靶点蛋白的致病分子机制研究
基于结构与功能的新型药物发现和开发

Publications

Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase, Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC, 2021
Berberine Protects C17.2 Neural Stem Cells from Oxidative Damage Followed by Inducing Neuronal Differentiation, Shou JW, Cheung CK, Gao J, Shi WW, Shaw PC, 2019
Structural and Functional Investigation and Pharmacological Mechanism of Trichosanthin, a Type 1 Ribosome-Inactivating Protein, Shi WW, Wong KB, Shaw PC, 2018
Structures and Ribosomal Interaction of Ribosome-Inactivating Proteins, Shi WW, Mak AN, Wong KB, Shaw PC, 2016
Crystal Structure of Ribosome-Inactivating Protein Ricin A Chain in Complex with the C-Terminal Peptide of the Ribosomal Stalk Protein P2, Shi WW, Tang YS, Sze SY, Zhu ZN, Wong KB, Shaw PC, 2016
Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins, Shi WW, Jiang YL, Zhu F, Yang YH, Shao QY, Yang HB, Ren YM, Wu H, Chen Y, Zhou CZ, 2014
Structures of the substrate-binding protein provide insights into the multiple compatible solutes binding specificities of Bacillus subtilis ABC transporter OpuC, Du Y, Shi WW, He YX, Yang YH, Zhou CZ, Chen Y, 2011

药物靶点发病机制分子机制蛋白质研究药物发现药物开发结构生物学生物化学分子生物学药理学

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