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Zhiyi Wei
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Neural Development
Disease
Membrane Domains
Assembly
Vesicle Transport
Intracellular
Signaling
Transmembrane
Protein
Mechanisms
Areas of Focus
- Molecular mechanisms of disease-related neural development
- Assembly mechanisms of functional membrane domains
- Intracellular vesicle transport mechanisms
- Transmembrane signaling mechanisms
- Protein machinery
Work Experience
- 2013 - Present, Southern University of Science and Technology, Associate Professor/Laboratory PI
- 2009 - 2013, Hong Kong University of Science and Technology, Research Assistant Professor
- 2007 - 2009, University of Washington (Seattle, USA), Postdoctoral Research Fellow
Academic Background & Achievements
- 2007 PhD in Biochemistry and Molecular Biology, University of Science and Technology of China
- 2002 Bachelor in Biology, University of Science and Technology of China
Publications
- Oligomerized liprin-α promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins, Liang M, Jin G, Xie X, Zhang W, Li K, Niu F, Yu C, Wei Z, 2021
- Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics, Yang H, Lin L, Sun K, Zhang T, Chen W, Li L, Xie Y, Wu C, Wei Z, Yu C, 2021
- F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis, Niu F, Sun K, Wei W, Yu C, Wei Z, 2020
- Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity, Xie X, Luo L, Liang M, Zhang W, Zhang T, Yu C, Wei Z, 2020
- Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2, Tang K, Li Y, Yu C, Wei Z, 2019
- Structures of the human PGD2 receptor CRTH2 reveal novel mechanisms for ligand recognition, Wang L, Yao D, Deepak RNVK, Liu H, Xiao Q, Fan H, Gong W, Wei Z, Zhang C, 2018
- Structural basis of kindlin-mediated integrin recognition and activation, Li H, Deng Y, Sun K, Yang H, Liu J, Wang M, Zhang Z, Lin J, Wu C, Wei Z, Yu C, 2017
- Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli, Zhao H, Sheng G, Wang J, Wang M, Bunkoczi G, Gong W, Wei Z, Wang Y, 2014
Awards
- 2021: Shenzhen Excellent Science and Technology Innovation Talent (Outstanding Youth Project)
- 2019: Southern University of Science and Technology 'President's Young Scientist Award'
- 2019: Shenzhen High-level Talent (National Level)
- 2016: Southern University of Science and Technology 'Outstanding Research Award'
- 2016: Guangdong Special Support Plan Science and Technology Innovation Young Top-notch Talent
- 2014: Shenzhen Overseas High-level Talent (Category B)
- 2011 - 2013: Tin Ka Ping Named Researcher, Hong Kong University of Science and Technology Advanced Research Institute
- 2007: Outstanding Graduate, University of Science and Technology of China
