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Qionghua Zhu
Life Science
Southern University of Science and Technology
Guangdong
Language: Chinese, German, English
Tumor
Evolution
Heterogeneity
Gene
Transcription
Regulation
Single-Cell
Genomics
Cancer
Biology
Areas of Focus
- Tumor evolution and tumor heterogeneity
- Gene transcription regulation
- Single-cell genomics
Work Experience
- 2019 - Present: Southern University of Science and Technology
- 2016 - 2019: Helmholtz Association Max Delbrück Center for Molecular Medicine
Academic Background & Achievements
- 2016 PhD: Humboldt University of Germany
Publications
- Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell lines, Zhu Q, 2023
- RUNX Proteins as Epigenetic Modulators in Cancer, Zhu Q, 2022
- The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling, Zhu Q, 2022
- A contraction-reaction-diffusion model for circular pattern formation in embryogenesis, Zhu Q, 2021
- CASB: A concanavalin A-based sample barcoding strategy for single-cell sequencing, Zhu Q, 2021
- Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT, Zhu Q, 2020
- CIGAR-seq, a CRISPR/Cas-based method for unbiased screening of novel mRNA modification regulators, Zhu Q, 2020
- Tracing tumorigenesis in a solid tumor model at single-cell resolution, Zhu Q, 2020
- The Wnt-driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer, Zhu Q, 2019
- CHOP activator LGH00168 induces necroptosis via reactive oxygen species-induced ER stress and NF-κB inhibition in A549 lung cancer cells, Zhu Q, 2016
- A small-molecule antagonist of the β-catenin/TCF4 interaction blocks the self-renewal of cancer stem cells and suppresses tumorigenesis, Zhu Q, 2016
- Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours, Zhu Q, 2013
