Professor | Bianhong Zhang | Asia Growth Partners

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Name

Bianhong Zhang

Contact Information

bhzhang@bio.ecnu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	East China Normal University
Faculty	Life Sciences
Academic Background & Achievements	2002/09 - 2009/04 PhD in Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS Bachelor of Biological Education from Shanxi Normal University, 2002
Work Experience	2014/01 - Present, East China Normal University, Institute of Life Sciences, Associate Professor 2013/12 - 2014/12, University of Virginia, School of Medicine, Department of Cell Biology, Visiting Scholar 2009/07 - 2013/12, East China Normal University, Institute of Life Sciences, Lecturer
Awards	2020, Second Prize in the Second Curriculum Ideological and Political Teaching Design Seminar and Collection Activity 2013, Seventh Excellent Undergraduate Tutor Award 2012, Ninth Young Teacher Teaching Competition, Third Prize

University/Lab Affiliation and Title

East China Normal University

Faculty

Life Sciences

Academic Background & Achievements

2002/09 - 2009/04 PhD in Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, CAS
Bachelor of Biological Education from Shanxi Normal University, 2002

Work Experience

2014/01 - Present, East China Normal University, Institute of Life Sciences, Associate Professor
2013/12 - 2014/12, University of Virginia, School of Medicine, Department of Cell Biology, Visiting Scholar
2009/07 - 2013/12, East China Normal University, Institute of Life Sciences, Lecturer

Awards

2020, Second Prize in the Second Curriculum Ideological and Political Teaching Design Seminar and Collection Activity
2013, Seventh Excellent Undergraduate Tutor Award
2012, Ninth Young Teacher Teaching Competition, Third Prize

Areas of Focus	Protein degradation pathways in tumor and immune-related diseases Protein degradation pathways in development and injury repair
Publications	Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma, Bianhong Zhang(＊), 2021 The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells, Bianhong Zhang(＊), 2020 REGγ controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells, Bianhong Zhang(＊), 2020 The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity, Bianhong Zhang(＊), 2019 Mutant p53 promotes cell spreading and migration via ARHGAP44, Bianhong Zhang(＊), 2017 Differential regulation of the REGγ-proteasome pathway by p53/TGFβ signaling and mutant p53 in cancer cells, Bianhong Zhang(＊), 2013 Site-specific acetylation of the proteasome activator REGγ directs its heptameric structure and functions, Bianhong Zhang(＊), 2013

Areas of Focus

Protein degradation pathways in tumor and immune-related diseases
Protein degradation pathways in development and injury repair

Publications

Reciprocal REGγ-mTORC1 regulation promotes glycolytic metabolism in hepatocellular carcinoma, Bianhong Zhang(＊), 2021
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells, Bianhong Zhang(＊), 2020
REGγ controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells, Bianhong Zhang(＊), 2020
The proteasome activator REGγ counteracts immunoproteasome expression and autoimmunity, Bianhong Zhang(＊), 2019
Mutant p53 promotes cell spreading and migration via ARHGAP44, Bianhong Zhang(＊), 2017
Differential regulation of the REGγ-proteasome pathway by p53/TGFβ signaling and mutant p53 in cancer cells, Bianhong Zhang(＊), 2013
Site-specific acetylation of the proteasome activator REGγ directs its heptameric structure and functions, Bianhong Zhang(＊), 2013

Protein Degradation Tumor Immune Diseases Pathways Mechanisms Regulation Development Injury Repair Cell Biology Molecular Biology

Shi Jiejun - Tongji University

Yixuan Wang - Tongji University

Jing Xie - Tongji University

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